Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Zoe Loomis"'
Autor:
Scott K. Ferguson, David I. Pak, Justin L. Hopkins, Julie W. Harral, Katherine M. Redinius, Zoe Loomis, Kurt R. Stenmark, Mark A. Borden, Thies Schroeder, David C. Irwin
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 147-157 (2019)
Hypoxic pulmonary vasoconstriction (HPV) is a well-characterized vascular response to low oxygen pressures and is involved in life-threatening conditions such as high-altitude pulmonary edema (HAPE) and pulmonary arterial hypertension (PAH). While th
Externí odkaz:
https://doaj.org/article/8473adc30be84cc5929c3946f8fac83b
Autor:
Zoe Loomis, Paul Eigenberger, Katherine Redinius, Christina Lisk, Vijaya Karoor, Eva Nozik-Grayck, Scott K Ferguson, Kathryn Hassell, Rachelle Nuss, Kurt R Stenmark, Paul W Buehler, David C Irwin
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173652 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0171219.].
Externí odkaz:
https://doaj.org/article/159f4039c667483dabd5f002a1d2160d
Autor:
Zoe Loomis, Paul Eigenberger, Katherine Redinius, Christina Lisk, Vijaya Karoor, Eva Nozik-Grayck, Scott K Ferguson, Kathryn Hassell, Rachelle Nuss, Kurt Stenmark, Paul Buehler, David C Irwin
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171219 (2017)
It is now well established that both inherited and acquired forms of hemolytic disease can promote pulmonary vascular disease consequent of free hemoglobin (Hb) induced NO scavenging, elevations in reactive oxygen species and lipid peroxidation. It h
Externí odkaz:
https://doaj.org/article/2f11fa6f21114d7e875df3abc1fd7289
Autor:
Zoe Loomis, David Irwin, Katherine Redinius, Thies Schroeder, David I. Pak, Justin L. Hopkins, Kurt R. Stenmark, Julie W. Harral, Scott K. Ferguson, Mark A. Borden
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 147-157 (2019)
Drug Delivery
Drug Delivery
Hypoxic pulmonary vasoconstriction (HPV) is a well-characterized vascular response to low oxygen pressures and is involved in life-threatening conditions such as high-altitude pulmonary edema (HAPE) and pulmonary arterial hypertension (PAH). While th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371730005138cbe774d9fdeb9fafdece
https://doaj.org/article/8473adc30be84cc5929c3946f8fac83b
https://doaj.org/article/8473adc30be84cc5929c3946f8fac83b
Autor:
David Irwin, Vijaya Karoor, Louis B. Hersh, Zoe Loomis, Evgenia V. Gerasimovskaya, Timothy M. Sullivan, Mehdi A. Fini, Edward C. Dempsey
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:154-163
Objective— Pulmonary artery smooth muscle cells (PASMCs) from neprilysin (NEP) null mice exhibit a synthetic phenotype and increased activation of Rho GTPases compared with their wild-type counterparts. Although Rho GTPases are known to promote a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3c06531a9ba54c5320edb49e690c50
https://doi.org/10.1161/atvbaha.117.310207
https://doi.org/10.1161/atvbaha.117.310207
Autor:
Mysan Le, Edward C. Dempsey, York E. Miller, Carol A. Wehling, Marilee J. Wick, Zoe Loomis, Julie W. Harral
Publikováno v:
Transgenic Research. 25:773-784
Neprilysin (NEP) is a cell surface metallopeptidase found in many tissues. Based mostly on pharmacological manipulations, NEP has been thought to protect blood vessels from plasma extravasation. We have suggested that NEP may protect against pulmonar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4faf7a2bdcdf3e19c99bfc105c38712
https://doi.org/10.1007/s11248-016-9969-x
https://doi.org/10.1007/s11248-016-9969-x
Autor:
David Irwin, Kandice Dixon, Travis Nemkov, Angelo D'Alessandro, Carolyn Valencia, Kurt R. Stenmark, Rubin M. Tuder, Zoe Loomis, Biruk Kassa, Claudia Mickael, Rajesh Kumar, Linda Sanders, Brian B. Graham, Mario J. Perez, Dan Koyanagi, Daniel Hernandez-Saavedra, Julie W. Harral, Li Zhang
Publikováno v:
American journal of respiratory cell and molecular biology, vol 59, iss 4
Optimal right ventricular (RV) function in pulmonary hypertension (PH) requires structural and functional coupling between the RV cardiomyocyte and its adjacent capillary network. Prior investigations have indicated that RV vascular rarefaction occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46327a5fd21557e23116ea498737c8b
https://escholarship.org/uc/item/85z3r59t
https://escholarship.org/uc/item/85z3r59t
Publikováno v:
Journal of Visualized Experiments.
Vascular leak, or plasma extravasation, has a number of causes, and may be a serious consequence or symptom of an inflammatory response. This study may ultimately lead to new knowledge concerning the causes of or new ways to inhibit or treat plasma e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f40f5a4a5321872abd8879d1784c65d
https://doi.org/10.3791/57037
https://doi.org/10.3791/57037
Autor:
Eva Nozik-Grayck, Zoe Loomis, Kurt R. Stenmark, Rachelle Nuss, Kathryn L. Hassell, David Irwin, Paul W. Buehler, Paul Eigenberger, Joanne Maltzahn, Christina Lisk, Jin Hyen Baek
Publikováno v:
Free Radical Biology and Medicine. 82:50-62
Haptoglobin (Hp) is an approved treatment in Japan for trauma, burns, and massive transfusion-related hemolysis. Additional case reports suggest uses in other acute hemolytic events that lead to acute kidney injury. However, Hp's protective effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31bd542456ecf8544e0346e17d5a4d1
https://doi.org/10.1016/j.freeradbiomed.2015.01.012
https://doi.org/10.1016/j.freeradbiomed.2015.01.012
Publikováno v:
Aerospace medicine and human performance. 87(12)
Background High altitude cerebral edema (HACE) is a fulminant, deadly, and yet still unpredictable brain disease. A new prophylactic treatment for HACE and its predecessor, acute mountain sickness (AMS), needs to be developed without the contraindica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949c6e7f40f975ae071be5ddc33d296d
https://pubmed.ncbi.nlm.nih.gov/28323589
https://pubmed.ncbi.nlm.nih.gov/28323589