Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zoe June Assaf"'
Autor:
Thomas Powles, Amanda Young, Halla Nimeiri, Russell W. Madison, Alexander Fine, Daniel R. Zollinger, Yanmei Huang, Chang Xu, Ole V. Gjoerup, Vasily N. Aushev, Hsin-Ta Wu, Alexey Aleshin, Corey Carter, Nicole Davarpanah, Viraj Degaonkar, Pratyush Gupta, Sanjeev Mariathasan, Erica Schleifman, Zoe June Assaf, Geoffrey Oxnard, Priti S. Hegde
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionCirculating tumor DNA (ctDNA) detection postoperatively may identify patients with urothelial cancer at a high risk of relapse. Pragmatic tools building off clinical tumor next-generation sequencing (NGS) platforms could have the potentia
Externí odkaz:
https://doaj.org/article/b572edde61804227913dfd5bf63af668
Autor:
Romain Banchereau, Ning Leng, Oliver Zill, Ethan Sokol, Gengbo Liu, Dean Pavlick, Sophia Maund, Li-Fen Liu, Edward Kadel, Nicole Baldwin, Suchit Jhunjhunwala, Dorothee Nickles, Zoe June Assaf, Daniel Bower, Namrata Patil, Mark McCleland, David Shames, Luciana Molinero, Mahrukh Huseni, Shomyseh Sanjabi, Craig Cummings, Ira Mellman, Sanjeev Mariathasan, Priti Hegde, Thomas Powles
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
PD-L1 immune checkpoint inhibition has been used for several tumour types. Here, the authors use immunohistochemistry, tumour mutation burden and RNA-seq data from 366 patients with different indications to identify molecular signatures of response t
Externí odkaz:
https://doaj.org/article/ae29efdfced64f11b4172bdb2e1a8bde
Autor:
Bernadett Szabados, Mark Kockx, Zoe June Assaf, Pieter-Jan van Dam, Alejo Rodriguez-Vida, Ignacio Duran, Simon J. Crabb, Michiel S. Van Der Heijden, Albert Font Pous, Gwenaelle Gravis, Urbano Anido Herranz, Andrew Protheroe, Alain Ravaud, Denis Maillet, Maria Jose Mendez, Cristina Suarez, Mark Linch, Aaron Prendergast, Charlotte Tyson, Diana Stanoeva, Sofie Daelemans, Miche Rombouts, Sanjeev Mariathasan, Joy S. Tea, Kelly Mousa, Shruti Sharma, Alexey Aleshin, Romain Banchereau, Daniel Castellano, Thomas Powles
Publikováno v:
European urology
[Background] Neoadjuvant immunotherapies hold promise in muscle-invasive bladder cancer (MIBC).
[Objective] To report on 2-yr disease-free (DFS) and overall (OS) survival including novel tissue-based biomarkers and circulating tumor DNA (ctDNA)
[Objective] To report on 2-yr disease-free (DFS) and overall (OS) survival including novel tissue-based biomarkers and circulating tumor DNA (ctDNA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52be113364becd0e44b3fcaf865708b0
https://doi.org/10.1016/j.eururo.2022.04.013
https://doi.org/10.1016/j.eururo.2022.04.013
Autor:
Sarah M. Paul, Filippo de Marinis, Rafal Dziadziuszko, David S. Shames, Shirish M. Gadgeel, Hye Ryun Kim, Todd Riehl, Natasha B. Leighl, Osvaldo Arén Frontera, Ernest Nadal, Mark Yan, Jorge Arturo Alatorre-Alexander, Daniel Shao-Weng Tan, Ji Youn Han, Maurice Pérol, Dae Ho Lee, Rajesh Patel, Simonetta Mocci, Zoe June Assaf, M. Mathisen, Erica B. Schleifman, Tony Mok, Solange Peters, Virote Sriuranpong, Gilberto de Castro Junior
Publikováno v:
Journal of Thoracic Oncology. 16:2040-2050
Introduction The Blood First Assay Screening Trial is an ongoing open-label, multicohort study, prospectively evaluating the relationship between blood-based next-generation sequencing (NGS) detection of actionable genetic alterations and activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a15ceaed5c35f5ec87841053c90dba5
https://doi.org/10.1016/j.jtho.2021.07.008
https://doi.org/10.1016/j.jtho.2021.07.008
Autor:
K. Schulz, A. Fine, J. Freidin, Mark A. Socinski, Geoffrey R. Oxnard, E. Polisecki, Makoto Nishio, A. Young, Namrata Patil, Craig Cummings, A. Rode, David S. Shames, Zoe June Assaf, Martin Reck, Mark Kennedy, Wei Zou
Publikováno v:
Journal of Thoracic Oncology. 16:S905-S906
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c165e2f439300290f43ede432b08bdc
https://doi.org/10.1016/j.jtho.2021.08.141
https://doi.org/10.1016/j.jtho.2021.08.141
Autor:
A. de Gramont, Michel Ducreux, Dirk Arnold, A. Grothey, Maurizio Perdicchio, Zoe June Assaf, Natsumi Irahara, E. Van Cutsem, Peter O'Dwyer, J. Tabernero, H.-J. Schmoll, M. Das Thakur, A. Tahiri
Publikováno v:
Annals of Oncology. 32:S221-S222
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::521825b65e9d4db5aeaa01cd586659af
https://doi.org/10.1016/j.annonc.2021.05.013
https://doi.org/10.1016/j.annonc.2021.05.013
Autor:
Daniel Bower, Mark McCleland, Nicole Baldwin, Thomas Powles, Sophia Maund, Craig Cummings, Zoe June Assaf, Namrata Patil, Luciana Molinero, Romain Banchereau, Priti Hegde, Gengbo Liu, Oliver A. Zill, Ira Mellman, Sanjeev Mariathasan, David S. Shames, Shomyseh Sanjabi, Mahrukh Huseni, Dean Pavlick, Ethan Sokol, Suchit Jhunjhunwala, Dorothee Nickles, Ning Leng, Edward E. Kadel, Li-Fen Liu
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature communications, vol 12, iss 1
Immune checkpoint inhibitors targeting the PD-1/PD-L1 axis lead to durable clinical responses in subsets of cancer patients across multiple indications, including non-small cell lung cancer (NSCLC), urothelial carcinoma (UC) and renal cell carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad67be8d59e3b329a51de497760337f7
https://pubmed.ncbi.nlm.nih.gov/34172722
https://pubmed.ncbi.nlm.nih.gov/34172722
Autor:
Thomas Reinert, Katrine Stribolt, Zoe June Assaf, Lene Hjerrild Iversen, Matthew Rabinowitz, Ryan Swenerton, Ramya Srinivasan, Samantha Navarro, Lars Dyrskjøt, Claus L. Andersen, Tenna V Henriksen, Anne-Sofie Kannerup, Søren Vang, Alexander Olson, Shruti Goel, Alexey Aleshin, Michael Knudsen, Scott Dashner, Styrmir Sigurjonsson, Mustafa Balcioglu, Emil Christensen, Anders Husted Madsen, Cheng-Ho Jimmy Lin, Raheleh Salari, Paul Billings, Himanshu Sethi, Søren Krag, Mads Rasmussen, Søren Laurberg, Shruti Sharma, Bernhard Zimmermann, Svetlana Shchegrova, Amanda Frydendahl Boll Johansen, Antony Tin, Dina Hafez, Hsin-Ta Wu, Iver Nordentoft, Kåre Gotschalck Sunesen
Publikováno v:
Reinert, T, Henriksen, T V, Christensen, E, Sharma, S, Salari, R, Sethi, H, Knudsen, M, Nordentoft, I, Wu, H-T, Tin, A S, Heilskov Rasmussen, M, Vang, S, Shchegrova, S, Frydendahl Boll Johansen, A, Srinivasan, R, Assaf, Z, Balcioglu, M, Olson, A, Dashner, S, Hafez, D, Navarro, S, Goel, S, Rabinowitz, M, Billings, P, Sigurjonsson, S, Dyrskjøt, L, Swenerton, R, Aleshin, A, Laurberg, S, Husted Madsen, A, Kannerup, A-S, Stribolt, K, Palmelund Krag, S, Iversen, L H, Gotschalck Sunesen, K, Lin, C-H J, Zimmermann, B G & Lindbjerg Andersen, C 2019, ' Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer ', JAMA Oncology, vol. 5, no. 8, pp. 1124-1131 . https://doi.org/10.1001/jamaoncol.2019.0528
Importance: Novel sensitive methods for detection and monitoring of residual disease can improve postoperative risk stratification with implications for patient selection for adjuvant chemotherapy (ACT), ACT duration, intensity of radiologic surveill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59acf069d0b5229abc11521aab11d94
https://pure.au.dk/ws/files/197692926/jamaoncology_reinert_2019_oi_190019.pdf
https://pure.au.dk/ws/files/197692926/jamaoncology_reinert_2019_oi_190019.pdf
Autor:
Ryan Swenerton, Lars Dyrskjøt, Dina Hafez, Zoe June Assaf, Alexey Aleshin, Mads Agerbæk, Samantha Navarro, Hsin-Ta Wu, Claus L. Andersen, Ramya Srinivasan, Emil Christensen, Antony Tin, Scott Dashner, Iver Nordentoft, Mustafa Balcioglu, Jørgen Bjerggaard Jensen, Karin Birkenkamp-Demtröder, Styrmir Sigurjonsson, Michael Knudsen, Sia Viborg Lindskrog, Bernhard Zimmermann, Philippe Lamy, Cheng-Ho Jimmy Lin, Ann Taber, Søren Vang, Alexander Olson, Thomas Reinert, Raheleh Salari, Svetlana Shchegrova, Himanshu Sethi, Shruti Sharma, Rosalyn Ram, Matthew Rabinowitz, Paul Billings
Publikováno v:
Christensen, E, Birkenkamp-Demtröder, K, Sethi, H, Shchegrova, S, Salari, R, Nordentoft, I, Wu, H-T, Knudsen, M, Lamy, P, Lindskrog, S V, Taber, A, Balcioglu, M, Vang, S, Assaf, Z, Sharma, S, Tin, A S, Srinivasan, R, Hafez, D, Reinert, T, Navarro, S, Olson, A, Ram, R, Dashner, S, Rabinowitz, M, Billings, P, Sigurjonsson, S, Andersen, C L, Swenerton, R, Aleshin, A, Zimmermann, B, Agerbæk, M, Lin, C-H J, Jensen, J B & Dyrskjøt, L 2019, ' Early Detection of Metastatic Relapse and Monitoring of Therapeutic Efficacy by Ultra-Deep Sequencing of Plasma Cell-Free DNA in Patients With Urothelial Bladder Carcinoma ', Journal of Clinical Oncology, vol. 37, no. 18, pp. 1547-1557 . https://doi.org/10.1200/JCO.18.02052
PURPOSE Novel sensitive methods for early detection of relapse and for monitoring therapeutic efficacy may have a huge impact on risk stratification, treatment, and ultimately outcome for patients with bladder cancer. We addressed the prognostic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc2a7402f41354ed6512f2af9d18c8b
https://pure.au.dk/portal/da/publications/early-detection-of-metastatic-relapse-and-monitoring-of-therapeutic-efficacy-by-ultradeep-sequencing-of-plasma-cellfree-dna-in-patients-with-urothelial-bladder-carcinoma(ae7edf8e-e90c-4709-9f9c-20a1316cbc31).html
https://pure.au.dk/portal/da/publications/early-detection-of-metastatic-relapse-and-monitoring-of-therapeutic-efficacy-by-ultradeep-sequencing-of-plasma-cellfree-dna-in-patients-with-urothelial-bladder-carcinoma(ae7edf8e-e90c-4709-9f9c-20a1316cbc31).html
Autor:
Gwenaelle Gravis, Mark M. Kockx, Romain Banchereau, Bernadett Szabados, Thomas Powles, B Valderrama, Albert Font Pous, B Zimmerman, Alexey Aleshin, Shruti Sharma, Urbano Anido Herranz, Alejo Rodriguez-Vida, Himanshu Sethi, Sanjeev Mariathasan, M.S. van der Heijden, A Prendergast, Simon J. Crabb, Zoe June Assaf, Daniel Castellano, A Ravauld
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 38:911
Background To explore the clinical utility of circulating tumor DNA (ctDNA) with neoadjuvant atezolizumab and radical cystectomy (RC) in muscle invasive urothelial bladder cancer (MIUC). Methods Forty patients from a phase II of neoadjuvant atezolizu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2144263c970fdd5b72d28b4a0b5484e4
https://doi.org/10.1016/j.urolonc.2020.10.069
https://doi.org/10.1016/j.urolonc.2020.10.069