Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Zoe Hoare"'
Autor:
Yu Jin Chung, Zoe Hoare, Friedrich Baark, Chak Shun Yu, Jia Guo, William Fuller, Richard Southworth, Doerthe M. Katschinski, Michael P. Murphy, Thomas R. Eykyn, Michael J. Shattock
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Elevated intracellular sodium Nai adversely affects mitochondrial metabolism and is a common feature of heart failure. The reversibility of acute Na induced metabolic changes is evaluated in Langendorff perfused rat hearts using the Na/K ATP
Externí odkaz:
https://doaj.org/article/8ac1f41d178b4502b68cf04de0eb6baa
Autor:
Aidan M. Michaels, Anna Zoccarato, Zoe Hoare, George Firth, Yu Jin Chung, Philip W. Kuchel, Ajay M. Shah, Michael J. Shattock, Richard Southworth, Thomas R. Eykyn
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background Glycolytic flux is regulated by the energy demands of the cell. Upregulated glycolysis in cancer cells may therefore result from increased demand for adenosine triphosphate (ATP), however it is unknown what this extra ATP turnover
Externí odkaz:
https://doaj.org/article/61fe531d26c740f2a46c9ccc1181bfa7
Autor:
Peter Fonagy, Rabih El Chammay, Carol Ngunu, Manasi Kumar, Lena Verdeli, Elizabeth Allison, Ghida Anani, Pasco Fearon, Fouad Fouad, Zoe Hoare, Lucina Koyio, Henrietta Moore, Andrew Nyandigisi, Stephen Pilling, Hannah Sender, Jolene Skordis, Rachel Evans, Gerard Joseph Abou Jaoude, Beatrice Madeghe, Sandra Pardi Arsen Maradian, Ciara O’Donnell, Elizabeth Simes, Alexandra Truscott, Grace Nduku Wambua, Obadia Yator
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Depression ranks as the foremost mental health concern among childbearing women. Within low- and middle-income countries (LMICs), between 20 and 25% of women encounter depression during pregnancy or soon after delivery. This condi
Externí odkaz:
https://doaj.org/article/493556dd1e5a45da9ca60038eaeed32c
Autor:
Priyanka Parijat, Seetharamaiah Attili, Zoe Hoare, Michael Shattock, Victor Kenyon, Thomas Kampourakis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Direct modulation of cardiac myosin function has emerged as a therapeutic target for both heart disease and heart failure. However, the development of myosin-based therapeutics has been hampered by the lack of targeted in vitro screening ass
Externí odkaz:
https://doaj.org/article/fdb3305c07434d8c93e33d876a8dec58
Autor:
Aida Suárez-González, Amber John, Emilie Brotherhood, Paul M. Camic, Roberta McKee-Jackson, Mel Melville, Mary Pat Sullivan, Rhiannon Tudor-Edwards, Gill Windle, Sebastian Crutch, Zoe Hoare, Joshua Stott, the Rare Dementia Support Impact team
Publikováno v:
Pilot and Feasibility Studies, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Background Non-memory-led dementias such as posterior cortical atrophy (PCA), primary progressive aphasia (PPA) and behavioural variant frontotemporal dementia (bvFTD) are low prevalent and often affect individuals under the age of 65. Tailo
Externí odkaz:
https://doaj.org/article/896a6a6176504ab48673eb2ba6163f3f
Autor:
Jennifer Rhiannon Roberts, Catherine Anne MacLeod, Zoe Hoare, Mary Pat Sullivan, Emilie Brotherhood, Joshua Stott, Gill Windle
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Background and objectives Policies to support people living with dementia increasingly focus on strengths-based approaches, highlighting the importance of building resilience. This research responds to the lack of a suitable resilience measu
Externí odkaz:
https://doaj.org/article/6eae053bf2184775bcff639b1d36ac97
Autor:
Emma Harding, Sam Rossi-Harries, Esther Vera Gerritzen, Nikki Zimmerman, Zoe Hoare, Danielle Proctor, Emilie Brotherhood, Sebastian Crutch, Aida Suárez-González
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background The public health measures imposed in many countries to contain the spread of COVID-19 resulted in significant suspensions in the provision of support and care for people with dementia. The negative effects of these measures have
Externí odkaz:
https://doaj.org/article/c2ca7033769344279c43f97af1cefa67
Autor:
Gerald McKenna, Georgios Tsakos, Sinead Watson, Alison Jenkins, Patricia Masterson Algar, Rachel Evans, Sarah R. Baker, Ivor G. Chestnutt, Craig J. Smith, Ciaran O’Neill, Zoe Hoare, Lynne Williams, Vicki Jones, Michael Donaldson, Anup Karki, Caroline Lappin, Kirstie Moons, Fiona Sandom, Mary Wimbury, Lorraine Morgan, Karen Shepherd, Paul Brocklehurst
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Dental service provision in the care home sector is poor, with little emphasis on prevention. Emerging evidence suggests that the use of Dental Care Professionals (dental therapists and dental nurses) as an alternative to dentists
Externí odkaz:
https://doaj.org/article/b8dc3895f9fc4670a5a4106a78eb9d55
Autor:
Bethany Fern Anthony, Stefanie Disbeschl, Nia Goulden, Annie Hendry, Julia Hiscock, Zoe Hoare, Jessica Roberts, Jan Rose, Alun Surgey, Nefyn Howard Williams, Daniel Walker, Richard Neal, Clare Wilkinson, Rhiannon Tudor Edwards
Publikováno v:
BJGP Open, Vol 7, Iss 1 (2023)
Background: UK cancer survival rates are much lower compared with other high-income countries. In primary care, there are opportunities for GPs and other healthcare professionals to act more quickly in response to presented symptoms that might repres
Externí odkaz:
https://doaj.org/article/b95af402d39e4c3eb591a77d48e9c9d5
Autor:
Annemarie Lodder, Anita Mehay, Hana Pavlickova, Zoe Hoare, Leandra Box, Jabeer Butt, Tim Weaver, Mike J. Crawford, Donna Clutterbuck, Nicola Westbrook, Karlet Manning, Saffron Karlsen, Steve Morris, Andrew Brand, Paul Ramchandani, Yvonne Kelly, Anja Heilmann, Richard G. Watt
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Up to 20% of UK children experience socio-emotional difficulties which can have serious implications for themselves, their families and society. Stark socioeconomic and ethnic inequalities in children’s well-being exist. Support
Externí odkaz:
https://doaj.org/article/1a149757fc4e41b9acc1eb6346ec3b54