Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zoe C. Yeoh"'
Autor:
Julien Olivet, Soon Gang Choi, Salvador Sierra, Tina M. O’Grady, Mario de la Fuente Revenga, Florent Laval, Vladimir V. Botchkarev, Christoph Gorgulla, Paul W. Coote, Jérémy Blavier, Ezekiel A. Geffken, Jimit Lakhani, Kijun Song, Zoe C. Yeoh, Bin Hu, Anthony C. Varca, Jonathan Bruyr, Samira Ibrahim, Tasneem Jivanjee, Joshua D. Bromley, Sarah K. Nyquist, Aaron Richardson, Hong Yue, Yang Wang, Natalia Calonghi, Alessandra Stefan, Kerstin Spirohn, Didier Vertommen, Maria F. Baietti, Irma Lemmens, Hyuk-Soo Seo, Mikhail G. Dozmorov, Luc Willems, Jan Tavernier, Kalyan Das, Eleonora Leucci, Alejandro Hochkoeppler, Zhen-Yu Jim Sun, Michael A. Calderwood, Tong Hao, Alex K. Shalek, David E. Hill, Andras Boeszoermenyi, Haribabu Arthanari, Sara J. Buhrlage, Sirano Dhe-Paganon, Javier González-Maeso, Franck Dequiedt, Jean-Claude Twizere, Marc Vidal
Enzymatic pockets such as those of histone deacetylases (HDACs) are among the most favored targets for drug development. However, enzymatic inhibitors often exhibit low selectivity and high toxicity due to targeting multiple enzyme paralogs, which ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8635e9e2aa438eb8f00e273e12bf49c9
https://doi.org/10.1101/2022.12.07.519454
https://doi.org/10.1101/2022.12.07.519454
Autor:
Kun Ping Lu, Hyuk-Soo Seo, Yujin Chun, Christopher M. Browne, Theresa D. Manz, Xiao Zhen Zhou, Zainab M. Doctor, Xiaolan Lian, Zoe C. Yeoh, Shin Kibe, Scott B. Ficarro, Nir London, Benika J. Pinch, Nicholas E. Vangos, Behnam Nabet, Stephen Buratowski, Dina Daitchman, Shingo Kozono, Daniel Zaidman, Nathanael S. Gray, Jarrod A. Marto, Mikaela L. Mohardt, Li Tan, Sirano Dhe-Paganon, Ezekiel A. Geffken
Publikováno v:
Nature chemical biology
Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 (Pin1) is commonly overexpressed in human cancers, including pancreatic ductal adenocarcinoma (PDAC). While Pin1 is dispensable for viability in mice, it is required for activated Ras to induce t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6565cbd6de180dcf92ba1d74b5e545e0
https://doi.org/10.1038/s41589-020-0550-9
https://doi.org/10.1038/s41589-020-0550-9
Autor:
Kyrillos Abdallah, Ethan Mathew, Jordan L. Page, Stephen C. Moss, Zoe C. Yeoh, Anthony Lohmeier, Sarah C. Keane, Breanna L. Johnson, Matt Ratanapanichkich, Anita Kotar, Gisselle Zuniga, Stanislav Cherepanov, Grace Arhin, Nicholas J. Tilson, Sara Jaime, Kyle J. Schaubroeck, Tracy L. Hodges, Brayden A. Bitterman, Mallak H. Taleb, Yaping Liu, Nicholas W. Morgenstern, Bruce A. Johnson
RNAs play myriad functional and regulatory roles in the cell. Despite their significance, three-dimensional structure elucidation of RNA molecules lags significantly behind that of proteins. NMR-based studies are often rate-limited by the assignment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615dbc47823a40bd52afd23d1633320b
https://doi.org/10.1101/2021.05.20.444957
https://doi.org/10.1101/2021.05.20.444957
Autor:
Lynda M. Rose, Yusuke Fukuda, Rosalind A. Segal, Ozge E. Tasdemir-Yilmaz, Jarrod A. Marto, Li Y, Sirano Dhe-Paganon, Bird Gh, Maria F. Pazyra-Murphy, Nicholas E. Vangos, Loren D. Walensky, Hyuk-Soo Seo, Ezekiel A. Geffken, Guillaume Adelmant, Zoe C. Yeoh
Complex neural circuitry requires stable connections formed by lengthy axons. To maintain these functional circuits, fast transport delivers RNAs to distal axons where they undergo local translation. However, the mechanism that enables long distance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba0c242c1ade50e2001e47a416fa1d59
Autor:
Roodolph St. Pierre, Lee Barrett, Clifford J. Woolf, Tom W. Muir, Hai T. Dao, Alfredo M. Valencia, Olubusayo Bolonduro, Zoe C. Yeoh, Clayton K. Collings, Crystal Hermawan, Cigall Kadoch, Yung-Chih Cheng, Zhen-Yu Sun, Mary K. Dornon, Nicholas E. Vangos, Dawn E. Comstock, Hyuk-Soo Seo, Sirano Dhe-Paganon, Nazar Mashtalir, Junwei Huang
Publikováno v:
Cell
Summary Mammalian switch/sucrose non-fermentable (mSWI/SNF) complexes are multi-component machines that remodel chromatin architecture. Dissection of the subunit- and domain-specific contributions to complex activities is needed to advance mechanisti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e62d2ea085e0e4c21a072c2e7881d8
https://pubmed.ncbi.nlm.nih.gov/31759698
https://pubmed.ncbi.nlm.nih.gov/31759698
Autor:
Reza Abdi, Leonard D. Shultz, Xiaolong Zhang, Dale L. Greiner, Jing Zhao, Yi-Jun Wang, Takaharu Ichimura, Ian Curtin, Zhen-Yu Jim Sun, Vivek Kasinath, Zoe C. Yeoh, Xiaofei Li, Qingming Hou, Naima Banouni, Gregory J. Heffron, Mayuko Uehara, Nicholas E. Vangos, Ezekiel A. Geffken, Liwei Jiang, Ze-Xian Liu, Li Dai, Sirano Dhe-Paganon, Hyuk-Soo Seo, Khalid Shah
Publikováno v:
Cell
Cancer therapies kill tumors either directly or indirectly by evoking immune responses and have been combined with varying levels of success. Here, we describe a paradigm to control cancer growth that is based on both direct tumor killing and the tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78acc246c0903739d13ccde7fc8f6f32
https://doi.org/10.1016/j.cell.2020.10.045
https://doi.org/10.1016/j.cell.2020.10.045