Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Zoe Alaniz"'
Autor:
Rasoul Pourebrahim, Rafael Heinz Montoya, Zoe Alaniz, Lauren Ostermann, Patrick P. Lin, Bin Liu, Edward Ayoub, Jared K. Burks, Michael Andreeff
Publikováno v:
Cell Death and Disease, Vol 14, Iss 6, Pp 1-11 (2023)
Abstract Mesenchymal stromal cells (MSCs) are a key component of the bone marrow (BM) niche, providing essential support required for the maintenance of hematopoietic stem cells. To advance our understanding of physiological functions of p53 and Mdm2
Externí odkaz:
https://doaj.org/article/1df39bffb885489bae594c472f52fdc8
Autor:
Hussein A. Abbas, Dapeng Hao, Katarzyna Tomczak, Praveen Barrodia, Jin Seon Im, Patrick K. Reville, Zoe Alaniz, Wei Wang, Ruiping Wang, Feng Wang, Gheath Al-Atrash, Koichi Takahashi, Jing Ning, Maomao Ding, Hannah C. Beird, Jairo T. Mathews, Latasha Little, Jianhua Zhang, Sreyashi Basu, Marina Konopleva, Mario L. Marques-Piubelli, Luisa M. Solis, Edwin Roger Parra, Wei Lu, Auriole Tamegnon, Guillermo Garcia-Manero, Michael R. Green, Padmanee Sharma, James P. Allison, Steven M. Kornblau, Kunal Rai, Linghua Wang, Naval Daver, Andrew Futreal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The response rate of relapsed/refractory acute myeloid leukemia patients to PD-1 checkpoint blockade is low and unpredictable. Authors here show by single cell RNA sequencing, T cell receptor profiling and genomic analysis that the phenotypes and rep
Externí odkaz:
https://doaj.org/article/28224d44710d40fe8758d8643917f98e
Autor:
Feng Wang, Wei Wang, Michael Green, Ruiping Wang, Jianhua Zhang, Andrew Futreal, Jing Ning, James Allison, Padmanee Sharma, Marina Konopleva, Latasha Little, Hussein Abbas, Katarzyna Tomczak, Praveen Barrodia, Jin Seon Im, Patrick Reville, Zoe Alaniz, Gheath Al-Atrash, Koichi Takahashi, Maomao Ding, Jairo Matthews, Sreyashi Basu, Guillermo Garcia-Manero, Steven Kornblau, Kunal Rai, Naval Daver
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/01c9173f79124520a0e23fa07c19006c
Autor:
Ghayas C. Issa, Aram Bidikian, Edward Ayoub, Feng Wang, Vakul Mohanty, Jake Leighton, Xiaogang Wu, Tallie Patsilevas, Zoe Alaniz, Jabra Zarka, Rashmi Kanagal-Shamanna, Naval Daver, Andy Futreal, Marina Konopleva, Nicholas Navin, Jianhua Zhang, Ken Chen, Michael Andreeff
Publikováno v:
Blood. 140:6267-6269
Autor:
Ghayas C. Issa, Vakul Mohanty, Edward Ayoub, Feng Wang, Jake Leighton, Xiaogang Wu, Aram Bidikian, Tallie Patsilevas, Zoe Alaniz, Jabra Zarka, Rashmi Kanagal-Shamanna, Andy Futreal, Naval Daver, Marina Konopleva, Nicholas Navin, Jianhua Zhang, Ken Chen, Michael Andreeff
Publikováno v:
Blood. 140:6323-6325
Autor:
Rasoul Pourebrahim, Rafael Heinz Montoya, Zoe Alaniz, Lauren Ostermann, Patrick P. Lin, Bin Liu, Edward Ayoub, Jared K. Burks, Michael Andreeff
Mesenchymal stromal cells (MSCs) are a key component of the bone marrow (BM) niche, providing essential support required for maintenance of hematopoietic stem cells. To advance our understanding of physiological functions of p53 and Mdm2 in BM-MSCs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eee70fe67344761e0303dd13ba2ae818
https://doi.org/10.21203/rs.3.rs-2544760/v1
https://doi.org/10.21203/rs.3.rs-2544760/v1
Autor:
Ghayas C. Issa, Elias Jabbour, Steven M. Kornblau, Matthew Cyr, Naval Daver, Mansour Alfayez, Guillermo Garcia-Manero, Jairo Matthews, Sean G Mackay, Zoe Alaniz, Hussein A. Abbas, Marina Konopleva, Jing Zhou, Michael Andreeff
Publikováno v:
Blood Advances
Key Points Effector polyfunctional index score of CD4 cells was more associated with responses to combined azacitidine/nivolumab than CD8 cells.Single-cell biomarker assays can be used in predicting responses to immune-based therapies.
Acute mye
Acute mye
Autor:
Ruiping Wang, Zoe Alaniz, Praveen Barrodia, Courtney D. DiNardo, Guillermo Garcia-Manero, Latasha Little, Michael R. Green, Koichi Takahashi, Gheath Alatrash, Wei Wang, Dapeng Hao, P. Andrew Futreal, Jairo Matthews, Jin S. Im, Farhad Ravandi, Steven M. Kornblau, Kunal Rai, Feng Wang, Maomao Ding, Linghua Wang, Jing Ning, Jianhua Zhang, Gautam Borthakur, Patrick K. Reville, James P. Allison, Naval Daver, Padmanee Sharma, Hussein A. Abbas, Marina Konopleva, Katarzyna Tomczak, Tapan M. Kadia, Sreyashi Basu
Publikováno v:
Blood. 136:29-31
Background The success of allogenic stem cell transplantation in curing AML suggests that the immune system can be harnessed to eradicate AML. In a phase 2 trial (NCT02397720) in relapsed/refractory (R/R) AML patients, we demonstrated that the azacit
Autor:
Michael Andreeff, Marcela Gronda, Yoosu Na, Rose Hurren, Xiaoming Wang, Neil MacLean, Andrea Arruda, Sara Mirali, Hyeonjeong Kang, Dilshad H. Khan, Zoe Alaniz, Marina Konopleva, Li Zhang, Mark D. Minden, Yulia Jitkova, Jongbok Lee, Aaron D. Schimmer, Mingjing Xu
Publikováno v:
Blood
The combination of venetoclax and the hypomethylating agent azacytidine induces a high rate of complete responses in treatment-naïve older patients with acute myeloid leukemia (AML). Lee and colleagues elucidate a novel mechanism of action for the s
Autor:
Guillermo Garcia-Manero, Dapeng Hao, Edwin R. Parra, Jairo T. Mathews, Naval Daver, Patrick K. Reville, Padmanee Sharma, Auriole Tamegnon, Latasha Little, Koichi Takahashi, Kunal Rai, Jin Seon Im, Feng Wang, Hussein A. Abbas, Wei Wang, Luisa M. Solis, Maomao Ding, Sreyashi Basu, Michael R. Green, Marina Konopleva, James P. Allison, Katarzyna Tomczak, Zoe Alaniz, Gheath Alatrash, Jing Ning, Wei Lu, Mario L. Marques-Piubelli, Andrew Futreal, Steven M. Kornblau, Hannah C. Beird, Praveen Barrodia, Ruiping Wang, Linghua Wang, Jianhua Zhang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
In contrast to the curative effect of allogenic stem cell transplantation in acute myeloid leukemia via T cell activity, only modest responses are achieved with checkpoint-blockade therapy, which might be explained by T cell phenotypes and T cell rec