Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Zoe, White"'
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Dysferlin-deficient limb-girdle muscular dystrophy type 2B (Dysf) mice are notorious for their mild phenotype. Raising plasma total cholesterol (CHOL) via apolipoprotein E (ApoE) knockout (KO) drastically exacerbates muscle wastin
Externí odkaz:
https://doaj.org/article/e8659e29265043dda704e01bf0dd7c5c
Publikováno v:
International Journal of Population Data Science, Vol 9, Iss 5 (2024)
Objective The Office for National Statistics (ONS) are developing a generalisable tool to facilitate the linkage of various datasets to its population-spine. However, a generalisable process requires that a variety of input datasets can be adaptively
Externí odkaz:
https://doaj.org/article/d991daac3ad3436aa579f9043418182d
Publikováno v:
International Journal of Population Data Science, Vol 9, Iss 5 (2024)
Objective The Office for National Statistics aim is to create a platform containing a variety of datasets interlinked via data spines. The resource burden linking this many datasets is high, and so research to maximise automation is a key aim of the
Externí odkaz:
https://doaj.org/article/d483c7442be243bfb2d65e1e6cefad52
Publikováno v:
International Journal of Population Data Science, Vol 9, Iss 5 (2024)
The quality of linkage techniques has a direct impact on the quality of statistics produced on the linked data, and as such, ensuring linkage algorithms are of the highest quality is a vital mission of the Office for National Statistics (ONS). Det
Externí odkaz:
https://doaj.org/article/efc7c52b01074e9d946459225212d455
Publikováno v:
International Journal of Population Data Science, Vol 8, Iss 2 (2023)
Data linkage traditionally uses deterministic and probabilistic methods. Alternatively, machine learning methods can be applied as classification algorithms, using the data to inform decisions. This project compared the quality, in terms of precision
Externí odkaz:
https://doaj.org/article/98ba2aa5e6e14f018fd252cec24e9001
Autor:
Zoe White, Zeren Sun, Elodie Sauge, Dan Cox, Graham Donen, Dmitri Pechkovsky, Volker Straub, Gordon A. Francis, Pascal Bernatchez
Publikováno v:
Skeletal Muscle, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Limb-girdle muscular dystrophy (MD) type 2B (LGMD2B) and Duchenne MD (DMD) are caused by mutations to the Dysferlin and Dystrophin genes, respectively. We have recently demonstrated in typically mild dysferlin- and dystrophin-deficient mouse
Externí odkaz:
https://doaj.org/article/530c71d83d4c4965bc91b84f18462a5a
Autor:
Arash Y. Tehrani, Zoe White, Lin Wei Tung, Roy Ru Yi Zhao, Nadia Milad, Michael A. Seidman, Elodie Sauge, Marine Theret, Fabio M. V. Rossi, Mitra Esfandiarei, Casey van Breemen, Pascal Bernatchez
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract There are no therapeutics that directly enhance chronic endothelial nitric oxide (NO) release, which is typically associated with vascular homeostasis. In contrast, angiotensin II (AngII) receptor type 1 (AT1R) blockers (ARBs) can attenuate
Externí odkaz:
https://doaj.org/article/74994e0921e04e798d335b260db5ee31
Autor:
Zoe White, Marine Theret, Nadia Milad, Lin Wei Tung, William Wei‐Han Chen, Martin G. Sirois, Fabio Rossi, Pascal Bernatchez
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 544-560 (2022)
Abstract Background Muscular dystrophy (MD) causes muscle wasting and is often lethal in patients due to a lack of proven therapies. In contrast, mouse models of MD are notoriously mild. We have previously shown severe human‐like muscle pathology i
Externí odkaz:
https://doaj.org/article/1734f6d867e74b1188de0ce7c5e14a22
Autor:
Mai Tsutsui, Chung Yan Cheung, Takeyuki Wada, Jen-erh Jaw, Cheng Wei Tony Yang, Pascal Bernatchez, Zoe White, Chen Xi Yang, Eun Jeong Annie Bae, Lauren H. Choi, Dan Gelbart, Samuel Lichtenstein, Lindsay Machan, Eran Elizur, Kim Wolff, Evan Goodacre, Marek Lipnicki, Denny Wong, Don D. Sin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Emphysema is a common phenotype of chronic obstructive pulmonary disease (COPD). Although resection of emphysematous tissue can improve lung mechanics, it is invasive and fraught with adverse effects. Meanwhile, radiofrequency (RF) treatment
Externí odkaz:
https://doaj.org/article/558ab3fdc7524a94b30981ea348c52c6
Publikováno v:
International Journal of Population Data Science, Vol 7, Iss 3 (2022)
Objectives The project aimed to test an alternative method to estimate the number of duplicate responses in the 2021 England and Wales Census. The method utilises information from all census records instead of relying on samples. It requires less cle
Externí odkaz:
https://doaj.org/article/1e3e76ad01bc4c3084c851c0c2d0718e