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Two-factor authentication underpins the precision of the piRNA pathway.

Autor: Dias Mirandela, Madeleine, Zoch, Ansgar, Leismann, Jessica, Webb, Shaun, Berrens, Rebecca V., Valsakumar, Devisree, Kabayama, Yuka, Auchynnikava, Tania, Schito, Martina, Chowdhury, Tamoghna, MacLeod, David, Xiang, Xinyu, Zou, Juan, Rappsilber, Juri, Allshire, Robin C., Voigt, Philipp, Cook, Atlanta G., Barau, Joan, O’Carroll, Dónal

Publikováno v: Nature; Oct2024, Vol. 634 Issue 8035, p979-985, 7p

SPOCD1 is an essential executor of piRNA-directed 1 de novo DNA methylation

Autor: Zoch, Ansgar, Auchynnikava, Tania, Berrens, Rebecca V., Kabayama, Yuka, Schöpp, Theresa, Heep, Madeleine, Vasiliauskaitė, Lina, Pérez-Rico, Yuvia A, Cook, Atlanta G., Shkumatava, Alena, Rappsilber, Juri, Allshire, Robin C., O'Carroll, Donal

Publikováno v: Zoch, A, Auchynnikava, T, Berrens, R V, Kabayama, Y, Schöpp, T, Heep, M, Vasiliauskaitė, L, Pérez-Rico, Y A, Cook, A G, Shkumatava, A, Rappsilber, J, Allshire, R C & O'Carroll, D 2020, ' SPOCD1 is an essential executor of piRNA-directed 1 de novo DNA methylation ', Nature, vol. 584, no. 7822, pp. 635-639 . https://doi.org/10.1038/s41586-020-2557-5

In mammals, the acquisition of the germline from the soma provides the germline with an essential challenge, the necessity to erase and reset genomic methylation. In the malegermline RNA-directed DNA methylation silences young active transposable ele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::add534c246aa6c66e423784761f1e911
https://hdl.handle.net/20.500.11820/4b4c7b36-91df-431f-8781-ec561331adc9

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Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation.

Autor: Zoch, Ansgar¹, Mayerl, Steffen¹, Schulz, Alexander¹, Greither, Thomas², Frappart, Lucien¹, Rübsam, Juliane¹, Heuer, Heike^1,3, Giovannini, Marco⁴, Morrison, Helen¹ helen@fli-leibniz.de

Publikováno v: PLoS ONE. 8/10/2015, Vol. 10 Issue 8, p1-25. 25p.