Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zoë A. Felton-Edkins"'
Autor:
Jingxin Zhang, Jacqueline Brodie, Ben A. Ramsbottom, Zoë A. Felton-Edkins, Elaine R. Kerr, Theodoros Kantidakis, Robert J. White, Fiona Innes, Carla Grandori, Dimitris Athineos, Sarah J. Goodfellow, Natividad Gomez-Roman, Niall S. Kenneth
Publikováno v:
Biochemical Society Symposia. 73:141-154
The proto-oncogene product c-Myc can induce cell growth and proliferation. It regulates a large number of RNA polymerase II-transcribed genes, many of which encode ribosomal proteins, translation factors and other components of the biosynthetic appar
Autor:
Carla Grandori, Zoë A. Felton-Edkins, Celine Ngouenet, Denise A. Galloway, Natividad Gomez-Roman, Robert N. Eisenman, Robert J. White
Publikováno v:
Nature Cell Biology. 7:311-318
c-Myc coordinates cell growth and division through a transcriptional programme that involves both RNA polymerase (Pol) II- and Pol III-transcribed genes. Here, we demonstrate that human c-Myc also directly enhances Pol I transcription of ribosomal RN
Autor:
Natividad Gomez-Roman, Timothy R. P. Brown, Niall S. Kenneth, Nicole L. Daly, Robert J. White, Carla Grandori, Robert N. Eisenman, Zoë A. Felton-Edkins
Publikováno v:
Cell Cycle. 2:180-183
The synthesis of tRNA and 5S rRNA by RNA polymerase (pol) III is cell cycle regulated in higher organisms. Overexpression of pol III products is a general feature of transformed cells. These observations may be explained by the fact that a pol III-sp
Autor:
Jennifer A. Fairley, Emma L. Graham, Imogen M. Johnston, Zoë A. Felton-Edkins, Pamela H. Scott, Robert J. White
Publikováno v:
The EMBO Journal. 22:2422-2432
RNA polymerase (pol) III transcription increases within minutes of serum addition to growth-arrested fibroblasts. We show that ERK mitogen-activated protein kinases regulate pol III output by directly binding and phosphorylating the BRF1 subunit of t
Autor:
Josephine E. Sutcliffe, Zoë A. Felton-Edkins, Robert J. White, Kerrie Tosh, Christopher G. C. Larminie, Andrew G. Winter
Publikováno v:
Molecular and Cellular Biology. 19:4927-4934
RNA polymerase (Pol) III transcription is abnormally active in fibroblasts that have been transformed by simian virus 40 (SV40). This report presents evidence that two separate components of the general Pol III transcription apparatus, TFIIIB and TFI
Autor:
Zoë A. Felton-Edkins, Dimitra Karali, Alexander Kondrashov, John R. Arrand, Lawrence S. Young, Robert J. White, Jennifer A. Fairley, Christopher W. Dawson
Publikováno v:
The Journal of biological chemistry. 281(45)
The EBER genes of Epstein-Barr virus (EBV) are transcribed by RNA polymerase (pol) III to produce untranslated RNAs that are implicated in oncogenesis. These EBER transcripts are the most highly expressed viral gene products in EBV-transformed cells.
Autor:
Zoë A, Felton-Edkins, Niall S, Kenneth, Timothy R P, Brown, Nicole L, Daly, Natividad, Gomez-Roman, Carla, Grandori, Robert N, Eisenman, Robert J, White
Publikováno v:
Cell cycle (Georgetown, Tex.). 2(3)
The synthesis of tRNA and 5S rRNA by RNA polymerase (pol) III is cell cycle regulated in higher organisms. Overexpression of pol III products is a general feature of transformed cells. These observations may be explained by the fact that a pol III-sp
Autor:
Zoë A. Felton-Edkins, Robert J. White
Publikováno v:
The Journal of biological chemistry. 277(50)
RNA polymerase (pol) III transcription is abnormally active in fibroblasts transformed by polyomavirus (Py) or simian virus 40 (SV40). Several distinct mechanisms contribute to this effect. In untransformed fibroblasts, the basal pol III transcriptio
RNA polymerase III Transcription — Its Control by Tumour Suppressors and Its Deregulation in Cancers
Autor:
Timothy R. P. Brown, Robert J. White, Kerrie Tosh, Hadi M. Alzuherri, Pamela H. Scott, George Sourvinos, Andrew G. Winter, Megan Bergkassel, Josephine E. Sutcliffe, Torsten Stein, Angela McLees, Christopher G. C. Larminie, Zoë A. Felton-Edkins, Carol A. Cairns, Simon J. Allison
Publikováno v:
Biochemical Society Transactions. 27:A66-A66