Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Zoë A. E. Waller"'
Autor:
Dilek Guneri, Effrosyni Alexandrou, Kamel El Omari, Zuzana Dvořáková, Rupesh V. Chikhale, Daniel T. S. Pike, Christopher A. Waudby, Christopher J. Morris, Shozeb Haider, Gary N. Parkinson, Zoë A. E. Waller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The insulin-linked polymorphic region is a variable number of tandem repeats region of DNA in the promoter of the insulin gene that regulates transcription of insulin. This region is known to form the alternative DNA structures, i-motifs and
Externí odkaz:
https://doaj.org/article/f3133e77e6154bdd947d113634a42cc4
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
i-Motifs are four-stranded DNA structures formed from sequences rich in cytosine, held together by hemi-protonated cytosine-cytosine base pairs. These structures have been utilized extensively as pH-switches in DNA-based nanotechnology. Recently ther
Externí odkaz:
https://doaj.org/article/b52a26d65c7b41eea2950237367ea4a5
Autor:
Alessia Pagano, Nunzia Iaccarino, Mahmoud A. S. Abdelhamid, Diego Brancaccio, Emanuele U. Garzarella, Anna Di Porzio, Ettore Novellino, Zoë A. E. Waller, Bruno Pagano, Jussara Amato, Antonio Randazzo
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
G-quadruplex (G4) and i-motif (iM) are four-stranded non-canonical nucleic acid structural arrangements. Recent evidences suggest that these DNA structures exist in living cells and could be involved in several cancer-related processes, thus represen
Externí odkaz:
https://doaj.org/article/d5d9b9c180dd4bdfb7a4144f37137c04
Autor:
Hanna K. Maliszewska, Mahmoud A. S. Abdelhamid, María J. Marín, Zoë A. E. Waller, María Paz Muñoz
The constant need for novel drugs has prompted the scientific community to explore alternative structures to natural products and small and medium size organic compounds used in classic medicinal and pharmaceutical chemistry. Since the discovery of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3e865bc8a9509d6286315bc4f8935a
https://ueaeprints.uea.ac.uk/id/eprint/91827/
https://ueaeprints.uea.ac.uk/id/eprint/91827/
Autor:
Zoë A. E. Waller
Publikováno v:
Handbook of Chemical Biology of Nucleic Acids ISBN: 9789811613135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47786ab851f5b17deef58f60ddff397a
https://doi.org/10.1007/978-981-16-1313-5_97-1
https://doi.org/10.1007/978-981-16-1313-5_97-1
Autor:
Sophie L. Williams, Corella S. Casas-Delucchi, Federica Raguseo, Dilek Guneri, Yunxuan Li, Masashi Minamino, Emma Elisabeth Fletcher, Joseph T. P. Yeeles, Ulrich F. Keyser, Zoë A. E. Waller, Marco Di Antonio, Gideon Coster
Sequences that can form DNA secondary structures, such as G-quadruplexes (G4s) and intercalated-Motifs (iMs), are abundant in the human genome and play a range of physiological roles. However, they can also pose a challenge to the replication machine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73cad152671fb4a67e2f71454ac05f6d
https://doi.org/10.1101/2022.11.18.517070
https://doi.org/10.1101/2022.11.18.517070
Autor:
Yasemin Yildizhan, Ying Xia, Zoë A. E. Waller, Rianne M. Lord, Ceyda Acilan, Baris Sergi, Ipek Bulut
Publikováno v:
ChemMedChem
Chemmedchem
Chemmedchem
To understand the potential in vitro modes of action of bis(β‐diketonato) oxovanadium(IV) complexes, nine compounds of varying functionality have been screened using a range of biological techniques. The antiproliferative activity against a range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74963f2bce68b9feb2b8c12f612412a0
https://doi.org/10.1002/cmdc.202100152
https://doi.org/10.1002/cmdc.202100152
Autor:
Susanta Haldar, Yashu Zhang, Ying Xia, Barira Islam, Sisi Liu, Francesco L. Gervasio, Adrian J. Mulholland, Zoë A. E. Waller, Dengguo Wei, Shozeb Haider
Publikováno v:
Journal of the American Chemical Society. 144(2)
The cationic porphyrin TMPyP4 is a well-established DNA G-quadruplex (G4) binding ligand that can stabilize different topologies via multiple binding modes. However, TMPyP4 can have both a stabilizing and destabilizing effect on RNA G4 structures. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5738e18fcee76bc7a27c52405183498b
https://pubmed.ncbi.nlm.nih.gov/34989224
https://pubmed.ncbi.nlm.nih.gov/34989224
Autor:
Zoë A. E. Waller, María Paz Muñoz, Ying Xia, Hanna K. Maliszewska, Carla Arnau Del Valle, María J. Marín
The incorporation of donor-type substituents on the allene core opens up the possibility of coordination complexes in which the metal is bonded to the donor groups, with or without interaction with the double bond system. Despite the challenges in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc4b6727b45745fec2d3ae02014d482
https://ueaeprints.uea.ac.uk/id/eprint/81980/
https://ueaeprints.uea.ac.uk/id/eprint/81980/
Autor:
Dengguo Wei, Susanta Haldar, Adrian J. Mulholland, Yashu Zhang, Francesco Luigi Gervasio, Ying Xia, Zoë A. E. Waller, Barira Islam, Sisi Liu, Shozeb Haider
The cationic porphyrin, TMPyP4, is a well-established DNA G-quadruplex (G4) binding ligand that can stabilize different topologies via multiple binding modes. However, TMPyP4 has completely opposite destabilizing and unwinding effect on RNA G4 struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7844ce19f4be5952ba8bd4dd0fd0851e
https://doi.org/10.1101/2021.10.26.465985
https://doi.org/10.1101/2021.10.26.465985