Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Zoé Schmal"'
Autor:
Claudia E. Rübe, Caroline Bäumert, Nadine Schuler, Anna Isermann, Zoé Schmal, Matthias Glanemann, Carl Mann, Harry Scherthan
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Cellular senescence is an irreversible growth arrest that occurs as a result of damaging stimuli, including DNA damage and/or telomere shortening. Here, we investigate histone variant H2A.J as a new biomarker to detect senescent cells during
Externí odkaz:
https://doaj.org/article/d87dc7743f364e58867d576df1284703
Autor:
Yanick Hippchen, Gargi Tewary, Daniela Jung, Zoé Schmal, Stephan Meessen, Jan Palm, Claudia E. Rübe
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 9830
Purpose: Precise molecular and cellular mechanisms of radiation-induced dermatitis are incompletely understood. Histone variant H2A.J is associated with cellular senescence and modulates senescence-associated secretory phenotype (SASP) after DNA-dama
Autor:
Zoé Schmal, Caroline Bäumert, Harry Scherthan, Nadine Schuler, Claudia E. Rübe, Carl Mann, Anna Isermann, Matthias Glanemann
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-11 (2021)
NPJ Aging and Mechanisms of Disease
NPJ Aging and Mechanisms of Disease
Cellular senescence is an irreversible growth arrest that occurs as a result of damaging stimuli, including DNA damage and/or telomere shortening. Here, we investigate histone variant H2A.J as a new biomarker to detect senescent cells during human sk
Autor:
Zoé Schmal, Claudia E. Rübe
Publikováno v:
Cancers; Volume 14; Issue 22; Pages: 5477
Background: Despite technical advances in hippocampus-sparing radiotherapy, radiation-induced injury to neural stem cell compartments may affect neurocognitive functions. In pre-clinical mouse models with fractionated low-dose radiation (FLDR) and si
Publikováno v:
International journal of radiation oncology, biology, physics. 111(5)
Purpose Despite major technical advances in hippocampus-sparing radiation therapy, radiation-induced injury to the neural stem cell compartment may affect neurocognitive functions. In the brain, glial cells modulate neuronal functions and are major m
Autor:
Mirit I. Aladjem, Régis Courbeyrette, Claudia E. Rübe, William M. Bonner, Adèle Mangelinck, Gargi Tewary, Christophe E. Redon, Jean-Yves Thuret, Carl Mann, Zoé Schmal
Publikováno v:
Genes, Vol 12, Iss 1665, p 1665 (2021)
Genes
Volume 12
Issue 11
Genes
Volume 12
Issue 11
H2A.J is a poorly studied mammalian-specific variant of histone H2A. We used immunohistochemistry to study its localization in various human and mouse tissues. H2A.J showed cell-type specific expression with a striking enrichment in luminal epithelia
Autor:
Soile Tapio, Christine von Toerne, Daniela Hladik, Anna Isermann, Claudia E. Rübe, Zoé Schmal
Publikováno v:
Radiother. Oncol. 137, 45-54 (2019)
Background and purpose: High-precision radiotherapy is an effective treatment modality for tumors. Intensity-modulated radiotherapy techniques permit close shaping of high doses to tumors, however healthy organs outside the target volume are repeated