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Akademický článek

Negri bodies are viral factories with properties of liquid organelles

Autor: Jovan Nikolic, Romain Le Bars, Zoé Lama, Nathalie Scrima, Cécile Lagaudrière-Gesbert, Yves Gaudin, Danielle Blondel

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

Negative strand RNA viruses, such as rabies virus, induce formation of cytoplasmic inclusions for genome replication. Here, Nikolic et al. show that these so-called Negri bodies (NBs) have characteristics of liquid organelles and they identify the mi

Externí odkaz: https://doaj.org/article/9a955e81f9324d589e3ef61679b3fd39

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Akademický článek

Rabies Virus Infection Induces the Formation of Stress Granules Closely Connected to the Viral Factories.

Autor: Jovan Nikolic, Ahmet Civas, Zoé Lama, Cécile Lagaudrière-Gesbert, Danielle Blondel

Publikováno v: PLoS Pathogens, Vol 12, Iss 10, p e1005942 (2016)

Stress granules (SGs) are membrane-less dynamic structures consisting of mRNA and protein aggregates that form rapidly in response to a wide range of environmental cellular stresses and viral infections. They act as storage sites for translationally

Externí odkaz: https://doaj.org/article/0653c14be34744c58da445c5f81c0010

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Kinase inhibitors tyrphostin 9 and rottlerin block early steps of rabies virus cycle

Autor: Danielle Blondel, Zoé Lama, Cécile Lagaudrière-Gesbert, Yves Gaudin

Publikováno v: Antiviral Research
Antiviral Research, 2019, ⟨10.1016/j.antiviral.2019.04.014⟩
Antiviral Research, Elsevier Masson, 2019, ⟨10.1016/j.antiviral.2019.04.014⟩

International audience; Rabies virus (RABV) is a neurotropic virus that causes fatal encephalitis in humans and animals and still kills up to 59,000 people worldwide every year. To date, only preventive or post-exposure vaccination protects against t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4453a2da34c1fa9088e891a17938846
https://doi.org/10.1016/j.antiviral.2019.04.014

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Rabies Virus Infection Induces the Formation of Stress Granules Closely Connected to the Viral Factories

Autor: Zoé Lama, Cécile Lagaudrière-Gesbert, Ahmet Civas, Danielle Blondel, Jovan Nikolic

Publikováno v: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2016, 12 (10), pp.e1005942. ⟨10.1371/journal.ppat.1005942⟩
PLoS Pathogens, 2016, 12 (10), pp.e1005942. ⟨10.1371/journal.ppat.1005942⟩
PLoS Pathogens, Vol 12, Iss 10, p e1005942 (2016)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cf2be2eaf32846568c0cb252ef46ad
https://hal.archives-ouvertes.fr/hal-02394338

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