Generation of isogenic control DJ-1-delP GC13 for the genetic Parkinson‘s disease-patient derived iPSC line DJ-1-delP (LCSBi008-A-1)

Autor: Pauline Mencke, Zoé Hanss, Javier Jarazo, François Massart, Arkadiusz Rybicki, Elizabet Petkovski, Enrico Glaab, Ibrahim Boussaad, Vincenzo Bonifati, Jens Christian Schwamborn, Wim Mandemakers, Rejko Krüger

Publikováno v: Stem Cell Research, Vol 62, Iss , Pp 102815- (2022)

We describe the generation of an isogenic control cell line DJ-1-delP GC13 from an induced pluripotent stem cell (iPSC) line DJ-1-delP LCSBi008-A that was derived from fibroblasts obtained from a Parkinson’s disease (PD) patient. Using CRISPR/Cas9

Externí odkaz: https://doaj.org/article/98b9fec390b8422c9118d59c5484a789

Induced pluripotent stem cell line (LCSBi001-A) derived from a patient with Parkinson's disease carrying the p.D620N mutation in VPS35

Autor: Simone B. Larsen, Zoé Hanss, Gérald Cruciani, François Massart, Peter A. Barbuti, George Mellick, Rejko Krüger

Publikováno v: Stem Cell Research, Vol 45, Iss , Pp - (2020)

Fibroblasts were obtained from a 76 year-old man diagnosed with Parkinson's disease (PD). The disease is caused by a heterozygous p.D620N mutation in VPS35. Induced pluripotent stem cells (iPSCs) were generated using the CytoTune™-iPS 2.0 Sendai Re

Externí odkaz: https://doaj.org/article/1fd6e290faa94a19a2ea0194c131c948

Plasma Amyloid Is Associated with White Matter and Subcortical Alterations and Is Modulated by Age and Seasonal Rhythms in Mouse Lemur Primates

Autor: Charlotte Gary, Anne-Sophie Hérard, Zoé Hanss, Marc Dhenain

Publikováno v: Frontiers in Aging Neuroscience, Vol 10 (2018)

Accumulation of amyloid-β (Aβ) peptides in the brain is a critical early event in the pathogenesis of Alzheimer's disease (AD), the most common age-related neurodegenerative disorder. There is increasing interest in measuring levels of plasma Aβ s

Externí odkaz: https://doaj.org/article/eaa4c1b49e214cbe863cc69f499e448f

Induced pluripotent stem cell line (LCSBi001-A) derived from a patient with Parkinson's disease carrying the p.D620N mutation in VPS35

Autor: George D. Mellick, Peter A. Barbuti, Gérald Cruciani, Zoé Hanss, Rejko Krüger, François Massart, Simone B. Larsen

Publikováno v: Stem Cell Research, Vol 45, Iss, Pp-(2020)
info:eu-repo/grantAgreement/EC/H2020/692320

Fibroblasts were obtained from a 76 year-old man diagnosed with Parkinson's disease (PD). The disease is caused by a heterozygous p.D620N mutation in VPS35. Induced pluripotent stem cells (iPSCs) were generated using the CytoTune™-iPS 2.0 Sendai Re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b46b90b0394c3a21677afbcb4175c7
http://www.sciencedirect.com/science/article/pii/S1873506120300805

Mitochondria interaction networks show altered topological patterns in Parkinson’s disease

Autor: Clara Berenguer-Escuder, Zoé Hanss, Weber J, Aidos Baumuratov, Feng He, Peter A. Barbuti, Massimiliano Zanin, Dajana Grossmann, Christophe Capelle, Markus Ollert, Paul Antony, Nico J. Diederich, Simone B. Larsen, Rejko Krüger, Rudi Balling, Bruno F.R. Santos

Publikováno v: npj Systems Biology and Applications, Vol 6, Iss 1, Pp 1-12 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
npj Systems Biology and Applications
Zanin, M, Santos, B F R, Antony, P M A, Berenguer-Escuder, C, Larsen, S B, Hanss, Z, Barbuti, P A, Baumuratov, A S, Grossmann, D, Capelle, C M, Weber, J, Balling, R, Ollert, M, Krüger, R, Diederich, N J & He, F Q 2020, ' Mitochondria interaction networks show altered topological patterns in Parkinson’s disease ', npj Systems Biology and Applications, vol. 6, 38 . https://doi.org/10.1038/s41540-020-00156-4
NPJ Systems Biology and Applications

Mitochondrial dysfunction is linked to pathogenesis of Parkinson’s disease (PD). However, individual mitochondria-based analyses do not show a uniform feature in PD patients. Since mitochondria interact with each other, we hypothesize that PD-relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060d3b104e64cc6b99c16bc5e5d4b0f2
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85095744360