Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Zizheng Zou"'
Autor:
Xiyuan Hu, Hongdou Liu, Tiao Luo, Ling Chen, Ting Peng, Min Wen, Wensong Luo, Qunfang Xu, Yuanzhu Xie, Mo Li, Mingquan Liu, Xiaohe Liu, Suyou Liu, Shuaiwen Zhu, Zizheng Zou, Zhiyong Luo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Triple-negative breast cancer (TNBC) is the most malignant molecular subtype of breast cancer and is characterized by aggressiveness, high mortality, significant heterogeneity, and poor prognosis. AMPK plays a critical role in maintaining th
Externí odkaz:
https://doaj.org/article/c3a9aed563ad47c3ba9afbccb37af2e6
Autor:
Wensong Luo, Zizheng Zou, Yuan Nie, Junli Luo, Zhengnan Ming, Xiyuan Hu, Tiao Luo, Min Ouyang, Mingquan Liu, Huicheng Tang, Yuanzhu Xie, Kunjian Peng, Ling Chen, Jiang Zhou, Zhiyong Luo
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract Argininosuccinate synthase (ASS1), a critical enzyme in the urea cycle, acts as a tumor suppressor in many cancers. To date, the anticancer mechanism of ASS1 has not been fully elucidated. Here, we found that phosphoglycerate dehydrogenase (
Externí odkaz:
https://doaj.org/article/3e87cb2a9e8e45e19bf13f4ea6df15fb
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundPancreatic cancer is one of most aggressive malignancies with a dismal prognosis. Activation of PI3K/AKT signaling is instrumental in pancreatic cancer tumorigenesis. The aims of this study were to identify the molecular clustering, prognos
Externí odkaz:
https://doaj.org/article/c2961c76f99642abaad35aa52a5092f2
Autor:
Zizheng Zou, Xiyuan Hu, Tiao Luo, Zhengnan Ming, Xiaodan Chen, Li Xia, Wensong Luo, Jijia Li, Na Xu, Ling Chen, Dongsheng Cao, Min Wen, Fanrong Kong, Kunjian Peng, Yuanzhu Xie, Xuan Li, Dayou Ma, Chuanyu Yang, Ceshi Chen, Wenjun Yi, Ousheng Liu, Suyou Liu, Junli Luo, Zhiyong Luo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Arginine addiction induced by argininosuccinate synthase (ASSN1) deficiency has been exploited to treat ASS1-deficient cancers. Here, the authors show an alternative therapeutic approach where ASS1 activity is increased by the pesticide spinosyn A an
Externí odkaz:
https://doaj.org/article/cdf3151bd1624747889b50910c492a74
Autor:
Yuanzhu Xie, Shuaiwen Zhu, Ling Chen, Hongdou Liu, Ting Peng, Zhengnan Ming, Zizheng Zou, Xiyuan Hu, Wensong Luo, Kunjian Peng, Yuan Nie, Tiao Luo, Dayou Ma, Suyou Liu, Zhiyong Luo
Publikováno v:
Cancers; Volume 15; Issue 9; Pages: 2424
Background: Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype, with shorter five-year survival than other breast cancer subtypes, and lacks targeted and hormonal treatment strategies. The signal transducer and activato