Výsledky vyhledávání

Machine learning-based phenotypic screening for postmitotic growth inducers uncover vitamin D3 metabolites as small molecule ribosome agonists

Autor: Zongmin Jiang, Liping Zhang, Ziyue Yao, Wenhua Cao, Shilin Ma, Yu Chen, Lu Guang, Zipeng Zheng, Chunwei Li, Kang Yu, Ng Shyh‐Chang

Publikováno v: Cell proliferation. 55(5)

To restore tissue growth without increasing the risk for cancer during aging, there is a need to identify small molecule drugs that can increase cell growth without increasing cell proliferation. While there have been numerous high-throughput drug sc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0680e7a0179065ed02ee91e15d620a
https://pubmed.ncbi.nlm.nih.gov/35411556

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Lin28a rejuvenates muscle stem cells via mitochondrial optimization

The well-conserved correlation between juvenility and tissue regeneration was first discussed by Charles Darwin. Ectopic Lin28 is known to play an important role in somatic reprogramming and tissue regeneration, but endogenous Lin28’s role in tissu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f6b0af4ac093c76f76f44103caa20e3
https://doi.org/10.1101/2021.10.14.462144

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Chromatin-modifying drugs and metabolites in cell fate control

Autor: Ziyue Yao, Wenhua Cao, Ng Shyh-Chang, Yu Chen

Publikováno v: Cell Proliferation

For multicellular organisms, it is essential to produce a variety of specialized cells to perform a dazzling panoply of functions. Chromatin plays a vital role in determining cellular identities, and it dynamically regulates gene expression in respon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e81dc43e65aaca504df6b92f1d6e62
https://pubmed.ncbi.nlm.nih.gov/32979011

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Akademický článek

Adult progenitor rejuvenation with embryonic factors.

Autor: Wang, Peng^1,2,3 (AUTHOR), Liu, Xupeng^1,2,3 (AUTHOR), Chen, Yu^1,2,3 (AUTHOR), Jun‐Hao, Elwin Tan^4,5,6,7 (AUTHOR), Yao, Ziyue^1,2,3 (AUTHOR), Min‐Wen, Jason Chua^4,5,6,7 (AUTHOR), Yan‐Jiang, Benjamin Chua^4,5,6,7 (AUTHOR), Ma, Shilin^1,2,3 (AUTHOR), Ma, Wenwu^1,2,3 (AUTHOR), Luo, Lanfang^1,2,3 (AUTHOR), Guo, Luyao^1,2,3 (AUTHOR), Song, Dan^1,2,3 (AUTHOR), Shyh‐Chang, Ng^1,2,3 (AUTHOR) huangsq@ioz.ac.cn

Publikováno v: Cell Proliferation. May2023, Vol. 56 Issue 5, p1-18. 18p.

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Akademický článek

Cover Image, Volume 139, Issue 26.

Autor: Jiang, Zongmin (AUTHOR), Zhang, Liping (AUTHOR), Yao, Ziyue (AUTHOR), Cao, Wenhua (AUTHOR), Ma, Shilin (AUTHOR), Chen, Yu (AUTHOR), Guang, Lu (AUTHOR), Zheng, Zipeng (AUTHOR), Li, Chunwei (AUTHOR), Yu, Kang (AUTHOR), Shyh‐Chang, Ng (AUTHOR)

Publikováno v: Cell Proliferation. May2022, Vol. 55 Issue 5, p1-1. 1p.

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Akademický článek

Machine learning‐based phenotypic screening for postmitotic growth inducers uncover vitamin D3 metabolites as small molecule ribosome agonists.

Autor: Jiang, Zongmin^1,2 (AUTHOR), Zhang, Liping^1,2,3 (AUTHOR), Yao, Ziyue^1,2,3 (AUTHOR), Cao, Wenhua^1,2,3 (AUTHOR), Ma, Shilin^1,2,3 (AUTHOR), Chen, Yu^1,2,3 (AUTHOR), Guang, Lu^1,2,3 (AUTHOR), Zheng, Zipeng⁴ (AUTHOR), Li, Chunwei⁴ (AUTHOR), Yu, Kang⁴ (AUTHOR) yuk1997@sina.com, Shyh‐Chang, Ng^1,2,3 (AUTHOR) huangsq@ioz.ac.cn

Publikováno v: Cell Proliferation. May2022, Vol. 55 Issue 5, p1-14. 14p.

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