Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ziyu Xun"'
Autor:
Chengpei Zhu, Yunchao Wang, Ruijuan Zhu, Shanshan Wang, Jingnan Xue, Dongya Zhang, Zhou Lan, Chenchen Zhang, Yajun Liang, Nan Zhang, Ziyu Xun, Longhao Zhang, Cong Ning, Xu Yang, Jiashuo Chao, Junyu Long, Xiaobo Yang, Hanping Wang, Xinting Sang, Xianzhi Jiang, Haitao Zhao
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background Accumulating evidence suggests that the gut microbiota and metabolites can modulate tumor responses to immunotherapy; however, limited data has been reported on biliary tract cancer (BTC). This study used metagenomics and metabolo
Externí odkaz:
https://doaj.org/article/2f4d512a2fa84cf9b124ce9859b81304
Autor:
Longhao Zhang, Shanshan Wang, Yajun Liang, Xiaobo Yang, Haitao Zhao, Xinting Sang, Dongya Zhang, Zhou Lan, Hanping Wang, Ziyu Xun, Chenchen Zhang, Chengpei Zhu, Jiashuo Chao, Zilun Pu, Cong Ning, Xianzhi Jiang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)
Background The association between gut bacteria and the response to immune checkpoint inhibitors (ICI) in hepatocellular carcinoma (HCC) has been studied; however, multi-kingdom gut microbiome alterations and interactions in ICI-treated HCC cohorts a
Externí odkaz:
https://doaj.org/article/ecd15d05f5644e09b41e04765b556c13
Autor:
Nan Zhang, Xu Yang, Mingjian Piao, Ziyu Xun, Yunchao Wang, Cong Ning, Xinmu Zhang, Longhao Zhang, Yanyu Wang, Shanshan Wang, Jiashuo Chao, Zhenhui Lu, Xiaobo Yang, Hanping Wang, Haitao Zhao
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-22 (2024)
Abstract Systemic therapies using programmed death-1 (PD-1) and programmed death ligand 1 (PD-L1) inhibitors have demonstrated commendable efficacy in some patients with advanced hepatocellular carcinoma (HCC); however, other individuals do not respo
Externí odkaz:
https://doaj.org/article/a79bfe8e5e4c47b2b9a876ec1ee87865
Genomic characterization and immunotherapy for microsatellite instability-high in cholangiocarcinoma
Autor:
Xu Yang, Baofeng Lian, Nan Zhang, Junyu Long, Yiran Li, Jingnan Xue, Xiangqi Chen, Yunchao Wang, Yanyu Wang, Ziyu Xun, Mingjian Piao, Chenpei Zhu, Shanshan Wang, Huishan Sun, Zhijian Song, Leilei Lu, Xiaowei Dong, Aodi Wang, Wenjin Liu, Jie Pan, Xiaorong Hou, Mei Guan, Li Huo, Jie Shi, Haohai Zhang, Jinxue Zhou, Zhenhui Lu, Yilei Mao, Xinting Sang, Liqun Wu, Xiaobo Yang, Kai Wang, Haitao Zhao
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Microsatellite instability-high (MSI-H) is a unique genomic status in many cancers. However, its role in the genomic features and immunotherapy in cholangiocarcinoma (CCA) is unclear. This study aimed to systematically investigate
Externí odkaz:
https://doaj.org/article/e96e78be7cfb426197e9dec8e4c18944
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-21 (2023)
Abstract Immune checkpoint blockade (ICB) has become a promising strategy in treating advanced cancers, providing significant survival benefits for patients with various cancer types. However, among the vast population of cancer patients, only a smal
Externí odkaz:
https://doaj.org/article/2bdb2bf889f4448fb078f6e34718b424
Autor:
Huishan Sun, Junyu Long, Bangyou Zuo, Yiran Li, Yu Song, Minghang Yu, Ziyu Xun, Yanyu Wang, Xi Wang, Xinting Sang, Haitao Zhao
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Selenium metabolism has been implicated in human health. This study aimed to identify a selenium metabolism regulator-based prognostic signature for hepatocellular carcinoma (HCC) and validate the role of INMT in HCC. Methods Tran
Externí odkaz:
https://doaj.org/article/682068a8add44da291e7c5cae8381e33
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Genomic instability is a characteristic of tumors, and recent studies have shown that it is related to a poor prognosis of multiple cancers. Long non-coding RNAs (lncRNAs) have become a research hotspot in recent years, and many unknown biological fu
Externí odkaz:
https://doaj.org/article/589ba3415dda4fc188969fe93e8c6e18
Autor:
Fucun Xie, Bowen Chen, Xu Yang, Huaiyuan Wang, Ge Zhang, Yanyu Wang, Yunchao Wang, Nan Zhang, Jingnan Xue, Junyu Long, Yiran Li, Huishan Sun, Ziyu Xun, Kai Liu, Xiangqi Chen, Yang Song, Xiaobo Yang, Zhenhui Lu, Yilei Mao, Xinting Sang, Yinying Lu, Haitao Zhao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundLenvatinib is a standard first-line systemic therapy in advanced hepatocellular carcinoma (aHCC) and is widely used in all lines. However, the efficacy and safety of immune checkpoint inhibitors (ICIs) plus molecular targeted agents (MTAs)
Externí odkaz:
https://doaj.org/article/fb348bd807e94787ae9b086c23530270
Autor:
Wanying Liao, Junyu Long, Yiran Li, Fucun Xie, Ziyu Xun, Yanyu Wang, Xu Yang, Yunchao Wang, Kang Zhou, Xinting Sang, Haitao Zhao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
N6-methyladenosine (m6A) and lncRNAs have been implicated in the development of colon cancer, including tumorigenesis, migration, and invasion. However, the specific effect of m6A regulators on lncRNAs is not clear, and m6A-related lncRNAs may be new
Externí odkaz:
https://doaj.org/article/59d14de566824751b4f6e156c0f620d7
Autor:
Bowen Huang, Jianzhou Liu, Jun Lu, Wenyan Gao, Li Zhou, Feng Tian, Yizhi Wang, Mingjie Luo, Dong Liu, Congyong Xie, Ziyu Xun, Chengxi Liu, Yu Wang, Haibo Ma, Junchao Guo
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Pancreatic cancer is a highly malignant tumor with a poor survival prognosis. We attempted to establish a robust prognostic model to elucidate the clinicopathological association between lncRNA, which may lead to poor prognosis by influencing m6A mod
Externí odkaz:
https://doaj.org/article/18d96563dd894a9c8e32d85bb3f43847