Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ziyu Le"'
Autor:
Li Chen, Wanzun Lin, Haojiong Zhang, Shikai Geng, Ziyu Le, Fangzhu Wan, Qingting Huang, Huaiyuan Chen, Xingyu Liu, Jiade J. Lu, Lin Kong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-15 (2024)
Abstract Tribbles pseudokinase 3 (TRIB3) has been identified recently as a novel oncogene in several cancers. Still, further extensive research is imperative to elucidate its function and the molecular mechanisms underlying its involvement in the pro
Externí odkaz:
https://doaj.org/article/fd7ea6fe581c42ddb8e2d1dbd50e0f77
Autor:
Wanzun Lin, Li Chen, Haojiong Zhang, Xianxin Qiu, Qingting Huang, Fangzhu Wan, Ziyu Le, Shikai Geng, Anlan Zhang, Sufang Qiu, Long Chen, Lin Kong, Jiade J. Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
YTHDF1 is an m6A reader that binds to methylated RNA and facilitates translation. Here the authors show that tumor intrinsic YTHDF1 promotes tumorigenesis by regulating lysosomal proteolysis of MHC-I and that YTHDF1 targeting boosts anti-tumor immuni
Externí odkaz:
https://doaj.org/article/4b73dcf1c1ca49ba94758647df26f8a5
Autor:
Ziyu Le, Dongmei Wu, Xuming Chen, Lei Wang, Yi Xu, Guoqi Zhao, Chengxiu Zhang, Ying Chen, Ye Hu, Shengyu Yao, Tingfeng Chen, Jiangping Ren, Guang Yang, Yong Liu
Publikováno v:
Radiotherapy and Oncology. 182:109489
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d45b8e1db0df68643d4d0ac7375e8f0
https://doi.org/10.1016/j.radonc.2023.109489
https://doi.org/10.1016/j.radonc.2023.109489
Publikováno v:
Life Sciences. 321:121594
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f9b4b5b92eb437136a439b7172e54cb
https://doi.org/10.1016/j.lfs.2023.121594
https://doi.org/10.1016/j.lfs.2023.121594
Autor:
Yongcheng Su, Beibei Xu, Jiangquan Li, Qianwen Shen, Ziyu Lei, Miaomiao Ma, Fuxing Zhang, Tianhui Hu
Publikováno v:
Annals of Medicine, Vol 55, Iss 1, Pp 1298-1316 (2023)
AbstractObjective This study aims to evaluate the prognostic value of m6A-associated long noncoding RNAs (lncRNAs) and their interaction with tumour microenvironment in thyroid cancer (THCA).Methods The clinical and gene expression data of tumours fr
Externí odkaz:
https://doaj.org/article/a6c1be496dd44af999ea458b8bcf7e35
Publikováno v:
Translational Cancer Research. 7:170-179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1943240ad8ae7b1ce3a5a5d6ab1b8222
https://doi.org/10.21037/tcr.2018.01.25
https://doi.org/10.21037/tcr.2018.01.25
Publikováno v:
International Journal of Molecular Medicine
The hypoxic microenvironment which is present following irradiation has been proven to promote radiation-induced injury to normal tissues. Previous studies have demonstrated that telomerase reverse transcriptase (TERT) is regulated by hypoxia, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c02e641674c8a26ded7873d5521c125
https://doi.org/10.3892/ijmm.2016.2673
https://doi.org/10.3892/ijmm.2016.2673
Autor:
Qi Liu, Ying Chen, Wenzhi Tu, Lin Kong, Xiaomin Ou, Ziyu Le, Guoqi Zhao, Yong Liu, Xiaoshuang Niu, Chaosu Hu
Publikováno v:
Oncotarget
The aim of this study was to investigate the association between the susceptibility of severe oral mucositis (OM) in Chinese nasopharyngeal carcinoma (NPC) patients treated with radiotherapy and single nucleotide polymorphisms (SNPs) across the whole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93de3befbe5deaae6ba661f36688f5d4
https://pubmed.ncbi.nlm.nih.gov/28968968
https://pubmed.ncbi.nlm.nih.gov/28968968
Autor:
Yongcheng Su, Fen Wang, Ziyu Lei, Jiangquan Li, Miaomiao Ma, Ying Yan, Wenqing Zhang, Xiaolei Chen, Beibei Xu, Tianhui Hu
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 142 (2023)
Limited studies have explored novel pancreatic cancer (PC) subtypes or prognostic biomarkers based on the altered activity of relevant signaling pathway gene sets. Here, we employed non-negative matrix factorization (NMF) to identify three immune sub
Externí odkaz:
https://doaj.org/article/19548ea4090b4c92b10eb18ca7dfbe71
Publikováno v:
Molecular Medicine Reports
Hypoxia is widely accepted as a fundamental biological phenomenon, which is strongly associated with tissue damage and cell viability under stress conditions. Insulin-like growth factor‑1 (IGF‑1) is known to protect tissues from multiple types of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9876d165813878649ca1200bd481b60c
https://pubmed.ncbi.nlm.nih.gov/28260056
https://pubmed.ncbi.nlm.nih.gov/28260056