Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Zixiu, Xiang"'
Autor:
Jerri Rook, Zixiu Xiang, Jonathan Dickerson, Shalini Dogra, Kendall Jensen, Insung Kim, Megan Ohler, Kelly Weiss, P. Jeffrey Conn
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Behavioral.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c500f4aeea526375bc0949b7c50816d
https://doi.org/10.1124/jpet.122.253010
https://doi.org/10.1124/jpet.122.253010
Autor:
Rocco G. Gogliotti, Weilun Qian, Ferdinando Nicoletti, Max E. Joffe, P. Jeffrey Conn, Shalini Dogra, Colleen M. Niswender, Branden J. Stansley, Craig W. Lindsley, Zixiu Xiang
Publikováno v:
Biological Psychiatry. 90:385-398
Background Polymorphisms in GRM3, the gene encoding the mGlu3 metabotropic glutamate receptor, are associated with impaired cognition and neuropsychiatric disorders such as schizophrenia. Limited availability of selective genetic and molecular tools
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cdb56df69d8bf35d7d940f7842fb7c
https://doi.org/10.1016/j.biopsych.2021.02.970
https://doi.org/10.1016/j.biopsych.2021.02.970
Autor:
Xin, Lin, Nicole M, Fisher, Shalini, Dogra, Rebecca K, Senter, Carson W, Reed, Jacob J, Kalbfleisch, Craig W, Lindsley, Wesley B, Asher, Zixiu, Xiang, Colleen M, Niswender, Jonathan A, Javitch
Publikováno v:
The Journal of biological chemistry. 298(10)
Glutamate acts at eight metabotropic glutamate (mGlu) receptor subtypes expressed in a partially overlapping fashion in distinct brain circuits. Recent evidence indicates that specific mGlu receptor protomers can heterodimerize and that these heterod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7f4c42c661608b83bf6eebb0aa05b58
https://pubmed.ncbi.nlm.nih.gov/36063995
https://pubmed.ncbi.nlm.nih.gov/36063995
Autor:
Colleen M. Niswender, P. Jeffrey Conn, Branden J. Stansley, Ayan Ghoshal, Rocco G. Gogliotti, Zixiu Xiang, Craig W. Lindsley, Xiaohui Lv, James Maksymetz
Publikováno v:
ACS Pharmacology & Translational Science. 2:198-209
[Image: see text] Metabotropic glutamate (mGlu) receptor type 5 (mGlu(5)) positive allosteric modulators (PAMs) enhance hippocampal long-term potentiation (LTP) and have cognition-enhancing effects in animal models. These effects were initially thoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7362ab26a06354b5fd86875dfae4fe7c
https://doi.org/10.1021/acsptsci.9b00017
https://doi.org/10.1021/acsptsci.9b00017
Autor:
Zixiu, Xiang, Xiaohui, Lv, Xin, Lin, Daniel E, O'Brien, Molly K, Altman, Craig W, Lindsley, Jonathan A, Javitch, Colleen M, Niswender, P Jeffrey, Conn
Publikováno v:
Sci Signal
Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that regulate various aspects of central nervous system processing in normal physiology and in disease. They are thought to function as disulfide-linked homodimers, but studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac13b2be884796b1312bc0e9c0555dda
https://pubmed.ncbi.nlm.nih.gov/33824180
https://pubmed.ncbi.nlm.nih.gov/33824180
Autor:
Colleen M. Niswender, Daniel E. O’Brien, Xiaohui Lv, Molly K. Altman, Zixiu Xiang, Craig W. Lindsley, Xin Lin, Jonathan A. Javitch, P. Jeffrey Conn
Publikováno v:
Science Signaling. 14
Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that regulate various aspects of central nervous system processing in normal physiology and in disease. They are thought to function as disulfide-linked homodimers, but studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0654c27203e610965cf23a871d5699d9
https://doi.org/10.1126/scisignal.abd2319
https://doi.org/10.1126/scisignal.abd2319
Autor:
Shalini, Dogra, Branden J, Stansley, Zixiu, Xiang, Weilun, Qian, Rocco G, Gogliotti, Ferdinando, Nicoletti, Craig W, Lindsley, Colleen M, Niswender, Max E, Joffe, P Jeffrey, Conn
Publikováno v:
Biol Psychiatry
Polymorphisms in GRM3, the gene encoding the mGluWe examined associative learning in mice with trace fear conditioning, a hippocampal-dependent learning task disrupted in patients with schizophrenia. Underlying cellular mechanisms were assessed using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65249085eae38c5b32ab362784b21f20
https://pubmed.ncbi.nlm.nih.gov/34446153
https://pubmed.ncbi.nlm.nih.gov/34446153
Autor:
Weilun Qian, Ferdinando Nicoletti, P. Jeffrey Conn, Zixiu Xiang, Colleen M. Niswender, Shalini Dogra, Max E. Joffe, Branden J. Stansley, Craig W. Lindsley, Rocco G. Gogliotti
BackgroundPolymorphisms in GRM3, the gene encoding the mGlu3 metabotropic glutamate receptor, are associated with impaired cognition and neuropsychiatric disorders such as schizophrenia. Limited availability of selective genetic and molecular tools h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b6ddc576604493384a6e2ef82da834d
https://doi.org/10.1101/2020.10.27.356196
https://doi.org/10.1101/2020.10.27.356196
Autor:
Aaron J. Yang, Charles F. Caskey, Thomas J. Manuel, Xiaoyan Zhan, Ellison Kang, Zixiu Xiang, Jiro Kusunose, Xiaohui Lv
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Ultrasound is gaining traction as a neuromodulation method due to its ability to remotely and non-invasively modulate neuronal activity with millimeter precision. However, there is little consensus about optimal ultrasound parameters required to elic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d042ea8c6e4684842881a9c8eb044b6e
http://europepmc.org/articles/PMC7501284
http://europepmc.org/articles/PMC7501284
Autor:
Max E. Joffe, James Maksymetz, Joseph R. Luschinger, Shalini Dogra, Anthony S. Ferranti, Deborah J. Luessen, Isabel M. Gallinger, Zixiu Xiang, Hannah Branthwaite, Patrick R. Melugin, Kellie M. Williford, Samuel W. Centanni, Brenda C. Shields, Craig W. Lindsley, Erin S. Calipari, Cody A. Siciliano, Colleen M. Niswender, Michael R. Tadross, Danny G. Winder, P. Jeffrey Conn
Publikováno v:
Neuron
Inhibitory interneurons orchestrate prefrontal cortex (PFC) activity, but we have a limited understanding of the molecular and experience-dependent mechanisms that regulate synaptic plasticity across PFC microcircuits. We discovered that mGlu(5) rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f7af40a821ab69bb15857ef09692fb
https://doi.org/10.1016/j.neuron.2021.12.027
https://doi.org/10.1016/j.neuron.2021.12.027