Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Zixiang Yu"'
Autor:
Hang Xiang, Rongkui Luo, Yunzhi Wang, Bing Yang, Sha Xu, Wen Huang, Shaoshuai Tang, Rundong Fang, Lingli Chen, Na Zhu, Zixiang Yu, Sujie Akesu, Chuanyuan Wei, Chen Xu, Yuhong Zhou, Jianying Gu, Jianyuan Zhao, Yingyong Hou, Chen Ding
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-35 (2024)
Abstract Melanoma is one of the most prevalent skin cancers, with high metastatic rates and poor prognosis. Understanding its molecular pathogenesis is crucial for improving its diagnosis and treatment. Integrated analysis of multi-omics data from 20
Externí odkaz:
https://doaj.org/article/4f4a78f6fcdc4f14b125f8102d0245f6
Autor:
Xin Peng, Xin Huang, Shaolu Zhang, Naixin Zhang, Shengfan Huang, Yingying Wang, Zhenxing Zhong, Shan Zhu, Haiwang Gao, Zixiang Yu, Xiaotong Yan, Zhennan Tao, Yuxiang Dai, Zhe Zhang, Xi Chen, Feng Wang, Francois X. Claret, Moshe Elkabets, Ning Ji, Yuxu Zhong, Dexin Kong
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract PARP inhibitors (PARPi) hold substantial promise in treating glioblastoma (GBM). However, the adverse effects have restricted their broad application. Through unbiased transcriptomic and proteomic sequencing, it is discovered that the BET in
Externí odkaz:
https://doaj.org/article/71a393bc885744d6a1d90f1327dd6a2c
Autor:
Shaoshuai Tang, Yunzhi Wang, Rongkui Luo, Rundong Fang, Yufeng Liu, Hang Xiang, Peng Ran, Yexin Tong, Mingjun Sun, Subei Tan, Wen Huang, Jie Huang, Jiacheng Lv, Ning Xu, Zhenmei Yao, Qiao Zhang, Ziyan Xu, Xuetong Yue, Zixiang Yu, Sujie Akesu, Yuqin Ding, Chen Xu, Weiqi Lu, Yuhong Zhou, Yingyong Hou, Chen Ding
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Soft tissue sarcoma is a broad family of mesenchymal malignancies exhibiting remarkable histological diversity. We portray the proteomic landscape of 272 soft tissue sarcomas representing 12 major subtypes. Hierarchical classification finds
Externí odkaz:
https://doaj.org/article/4f0b0a6f461944f78d25288bc5190ec0
Publikováno v:
Food Chemistry: X, Vol 20, Iss , Pp 100905- (2023)
This study employed proline, glucose, and water to prepare natural deep eutectic solvents (NADES) through heating and stirring. The Maillard reaction was then performed, producing a high yield of Amadori rearrangement product (ARP) and physicochemica
Externí odkaz:
https://doaj.org/article/0a718f04f9fe4421b1b32dc03051b2dc
Autor:
Lingling Li, Dongxian Jiang, Hui Liu, Chunmei Guo, Rui Zhao, Qiao Zhang, Chen Xu, Zhaoyu Qin, Jinwen Feng, Yang Liu, Haixing Wang, Weijie Chen, Xue Zhang, Bin Li, Lin Bai, Sha Tian, Subei Tan, Zixiang Yu, Lingli Chen, Jie Huang, Jian-Yuan Zhao, Yingyong Hou, Chen Ding
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Duodenal cancer (DC) has complex subtypes and undergoes complicated morphological changes throughout progression, so understanding the molecular basis is crucial. Here, the authors perform a proteogenomics analysis of 156 DCs, revealing molecular sub
Externí odkaz:
https://doaj.org/article/e73ae132dc0f4a55886749550e4a6bb7
Autor:
Yunzhi Wang, Rongkui Luo, Xuan Zhang, Hang Xiang, Bing Yang, Jinwen Feng, Mengjie Deng, Peng Ran, Akesu Sujie, Fan Zhang, Jiajun Zhu, Subei Tan, Tao Xie, Pin Chen, Zixiang Yu, Yan Li, Dongxian Jiang, Xiaobiao Zhang, Jian-Yuan Zhao, Yingyong Hou, Chen Ding
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-32 (2023)
The proteogenomic landscape of diffuse gliomas remains to be explored. Here, the authors perform proteogenomic characterisation of diffuse gliomas, investigate the functional role of genomic alterations and suggest three proteomic subgroups.
Externí odkaz:
https://doaj.org/article/1d9161a18c684bffaa32bb2b98621ff1
Autor:
Qi Song, Ye Yang, Dongxian Jiang, Zhaoyu Qin, Chen Xu, Haixing Wang, Jie Huang, Lingli Chen, Rongkui Luo, Xiaolei Zhang, Yufeng Huang, Lei Xu, Zixiang Yu, Subei Tan, Minying Deng, Ruqun Xue, Jingbo Qie, Kai Li, Yanan Yin, Xuetong Yue, Xiaogang Sun, Jieakesu Su, Fuchu He, Chen Ding, Yingyong Hou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Squamous cell carcinomas are an aggressive cancer type which can occur in multiple organ systems. Here, the authors analyse the proteome of SCC cancers from 17 organs and show commonly dysregulated proteins independent of location.
Externí odkaz:
https://doaj.org/article/05d0671cbe88464bab2dc69a85f38421
Autor:
Xin Peng, Shaolu Zhang, Yingying Wang, Zhicheng Zhou, Zixiang Yu, Zhenxing Zhong, Liang Zhang, Zhe‐Sheng Chen, Francois X. Claret, Moshe Elkabets, Feng Wang, Fan Sun, Ran Wang, Han Liang, Hou‐Wen Lin, Dexin Kong
Publikováno v:
Advanced Science, Vol 10, Iss 3, Pp n/a-n/a (2023)
Abstract Glioblastoma (GBM) is the most aggressive type of cancer. Its current first‐line postsurgery regimens are radiotherapy and temozolomide (TMZ) chemotherapy, both of which are DNA damage‐inducing therapies but show very limited efficacy an
Externí odkaz:
https://doaj.org/article/4f5319a95b1f4014976c1ba1ab1fe669
Autor:
Dongxian Jiang, Qi Song, Xiaojun Wei, Zixiang Yu, Yufeng Liu, Haixing Wang, Xingxing Wang, Jie Huang, Jieakesu Su, Yang Hong, Yifan Xu, Chen Xu, Yingyong Hou
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundDNA mismatch repair (MMR) deficiency (dMMR) has been recognized as an important biomarker for immunotherapy in esophageal squamous cell carcinoma (ESCC), along with programmed death ligand 1 (PD-L1) expression and/or tumor-infiltrated lymph
Externí odkaz:
https://doaj.org/article/2b2c3aec4fb24d73ad80a0e414cb3ca4
Publikováno v:
Virology Journal, Vol 15, Iss 1, Pp 1-7 (2018)
Abstract Background Iris yellow spot virus (IYSV) is an Orthotospovirus that infects most Allium species. Very few approaches for specific detection of IYSV from infected plants are available to date. We report the development of a high-sensitive Lum
Externí odkaz:
https://doaj.org/article/c9c61fa1bf254124bba47f33824a3212