Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ziwan Xu"'
Autor:
Xiaomin Jiang, Wenbo Han, Jianqiao Liu, Jianming Mao, Morten J. Lee, Megan Rodriguez, Youyou Li, Taokun Luo, Ziwan Xu, Kaiting Yang, Marc Bissonnette, Ralph R. Weichselbaum, Wenbin Lin
Publikováno v:
Advanced Science, Vol 9, Iss 24, Pp n/a-n/a (2022)
Abstract The binding of plasma proteins to nanomedicines is widely considered detrimental to their delivery to tumors. Here, the design of OxPt/SN38 nanoparticle containing a hydrophilic oxaliplatin (OxPt) prodrug in a coordination polymer core and a
Externí odkaz:
https://doaj.org/article/50066efeaa414d2cb1308b46e06314f1
Autor:
Kaiting Yang, Wenbo Han, Xiaomin Jiang, Andras Piffko, Jason Bugno, Chuanhui Han, Sirui Li, Hua Liang, Ziwan Xu, Wenxin Zheng, Liangliang Wang, Jiaai Wang, Xiaona Huang, Jenny P. Y. Ting, Yang-Xin Fu, Wenbin Lin, Ralph R. Weichselbaum
Publikováno v:
Nature Nanotechnology. 17:1322-1331
The clinical utility of stimulator of interferon genes (STING) agonists has been limited due to poor tumour-targeting and unwanted toxicity following systemic delivery. Here we describe a robust tumour-targeted STING agonist, ZnCDA, formed by the enc
Publikováno v:
J Am Chem Soc
Herein, we report that dimensional reduction from three-dimensional nanoscale metal-organic frameworks (nMOFs) to two-dimensional nanoscale metal-organic layers (nMOLs) increases the encounters between PSs and oxygen and facilitates the diffusion of
Autor:
Kaiyuan Ni, Ziwan Xu, August Culbert, Taokun Luo, Nining Guo, Kaiting Yang, Erik Pearson, Ben Preusser, Tong Wu, Patrick La Riviere, Ralph R. Weichselbaum, Michael T. Spiotto, Wenbin Lin
Publikováno v:
Nat Biomed Eng
Checkpoint blockade elicits durable responses in immunogenic cancers, but it is largely ineffective in immunologically ‘cold’ tumours. Here, we report the design, synthesis and performance of a Bismuth-based nanoscale metal-organic framework that
Publikováno v:
Accounts of Materials Research. 2:944-953
Publikováno v:
Journal of the American Chemical Society
The performance of photodynamic therapy (PDT) depends on the solubility, pharmacokinetic behaviors, and photophysical properties of photosensitizers (PSs). However, highly conjugated PSs with strong reactive oxygen species (ROS) generation efficiency
Publikováno v:
Angewandte Chemie International Edition. 61
High-Z metal-based nanoscale metal-organic frameworks (nMOFs) with photosensitizing ligands can enhance radiation damage to tumors via a unique radiotherapy-radiodynamic therapy (RT-RDT) process. Here we report Monte Carlo (MC) simulation-guided desi
Autor:
Kaiyuan Ni, Ziwan Xu, August Culbert, Taokun Luo, Nining Guo, Kaiting Yang, Erik Pearson, Ben Preusser, Tong Wu, Patrick La Riviere, Ralph R. Weichselbaum, Michael T. Spiotto, Wenbin Lin
Publikováno v:
Nature Biomedical Engineering. 6:1449-1450
Autor:
Deyan Gong, Wenbin Lin, Wenjie Shi, Ziwan Xu, Xiang Ling, Guangxu Lan, Youyou Li, Wenbo Han, Wenwu Qin
Publikováno v:
J Am Chem Soc
Mitochondrial dysregulation controls cell death and survival by changing endogenous molecule concentrations and ion flows across the membrane. Here, we report the design of a triply emissive nanoscale metal–organic layer (nMOL), NA@Zr-BTB/F/R, for
Publikováno v:
ACS Catalysis. 11:1024-1032
We report here the construction of two metal–organic frameworks (MOFs), Zr6-Cu/Fe-1 and Zr6-Cu/Fe-2, by integrating earth-abundant cuprous photosensitizers (Cu-PSs) and Fe catalysts for photocataly...