Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Zivia Brunschwig"'
Autor:
Yoram Nevo, Shlomit Aga-Mizrachi, Edva Elmakayes, Nurit Yanay, Keren Ettinger, Moran Elbaz, Zivia Brunschwig, Oshrat Dadush, Galit Elad-Sfadia, Roni Haklai, Yoel Kloog, Joab Chapman, Shimon Reif
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18049 (2011)
The Ras superfamily of guanosine-triphosphate (GTP)-binding proteins regulates a diverse spectrum of intracellular processes involved in inflammation and fibrosis. Farnesythiosalicylic acid (FTS) is a unique and potent Ras inhibitor which decreased i
Externí odkaz:
https://doaj.org/article/3e0e0395acd2471d8f1ed6eb1990aded
Autor:
Elad Horwitz, Ludmila Rivkin, Hilla Giladi, Eylon Yavin, Abed Khalaileh, Zivia Brunschwig, Yael Hants, Rami Eliakim, Ayala Hubert, Maor Lahav, Amotz Shemi, Elina Zorde Khvalevsky, Eithan Galun, Yael Kopelman, Rinat Abramovitch, Adva Shemi, Ariel Orbach, Eran Goldin, A Dancour, Sagit Arbel-Alon, Abraham J. Domb, Talia Golan, Itzhak Haim Rachmut, Alina Simerzin, Racheli Gabai
Publikováno v:
Proceedings of the National Academy of Sciences. 110:20723-20728
Pancreatic ductal adenocarcinoma (PDA) represents an unmet therapeutic challenge. PDA is addicted to the activity of the mutated KRAS oncogene which is considered so far an undruggable therapeutic target. We propose an approach to target KRAS effecti