Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Ziva, Misulovin"'
Publikováno v:
PLoS Genetics, Vol 14, Iss 2, p e1007225 (2018)
The cohesin complex topologically encircles chromosomes and mediates sister chromatid cohesion to ensure accurate chromosome segregation upon cell division. Cohesin also participates in DNA repair and gene transcription. The Nipped-B-Mau2 protein com
Externí odkaz:
https://doaj.org/article/6769836d2c324b8bac3210c497ca0e7f
Autor:
Amanda Swain, Ziva Misulovin, Michelle Pherson, Maria Gause, Kathie Mihindukulasuriya, Ryan A Rickels, Ali Shilatifard, Dale Dorsett
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006331 (2016)
The cohesin protein complex mediates sister chromatid cohesion and participates in transcriptional control of genes that regulate growth and development. Substantial reduction of cohesin activity alters transcription of many genes without disrupting
Externí odkaz:
https://doaj.org/article/12378e1de09c460384bc504f26134fa3
Autor:
Yaning Wu, Maria Gause, Dongbin Xu, Ziva Misulovin, Cheri A Schaaf, Ramya C Mosarla, Elizabeth Mannino, Megan Shannon, Emily Jones, Mi Shi, Wen-Feng Chen, Olivia L Katz, Amita Sehgal, Thomas A Jongens, Ian D Krantz, Dale Dorsett
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005655 (2015)
Individuals with Cornelia de Lange Syndrome (CdLS) display diverse developmental deficits, including slow growth, multiple limb and organ abnormalities, and intellectual disabilities. Severely-affected individuals most often have dominant loss-of-fun
Externí odkaz:
https://doaj.org/article/8f9fec2959ca49adb0fe3c3b042b0b61
Autor:
Cheri A Schaaf, Ziva Misulovin, Maria Gause, Amanda Koenig, David W Gohara, Audrey Watson, Dale Dorsett
Publikováno v:
PLoS Genetics, Vol 9, Iss 6, p e1003560 (2013)
Cohesin is crucial for proper chromosome segregation but also regulates gene transcription and organism development by poorly understood mechanisms. Using genome-wide assays in Drosophila developing wings and cultured cells, we find that cohesin func
Externí odkaz:
https://doaj.org/article/f33621fa633540abb4c74cce7db9e9c7
Autor:
Cheri A Schaaf, Hojoong Kwak, Amanda Koenig, Ziva Misulovin, David W Gohara, Audrey Watson, Yanjiao Zhou, John T Lis, Dale Dorsett
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003382 (2013)
Cohesin is a well-known mediator of sister chromatid cohesion, but it also influences gene expression and development. These non-canonical roles of cohesin are not well understood, but are vital: gene expression and development are altered by modest
Externí odkaz:
https://doaj.org/article/c865d1a9c18f495899954287dcc1955d
Autor:
Adeleye, Opejin, Alexey, Surnov, Ziva, Misulovin, Michelle, Pherson, Cindy, Gross, Courtney A, Iberg, Ian, Fallahee, Jessica, Bourque, Dale, Dorsett, Daniel, Hawiger
Publikováno v:
Cell reports
SUMMARY Various processes induce and maintain immune tolerance, but effector T cells still arise under minimal perturbations of homeostasis through unclear mechanisms. We report that, contrary to the model postulating primarily tolerogenic mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f56a9dc9639adbccb2692a40ef217ef
https://pubmed.ncbi.nlm.nih.gov/33238127
https://pubmed.ncbi.nlm.nih.gov/33238127
Autor:
Cheri A Schaaf, Ziva Misulovin, Gurmukh Sahota, Akbar M Siddiqui, Yuri B Schwartz, Tatyana G Kahn, Vincenzo Pirrotta, Maria Gause, Dale Dorsett
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6202 (2009)
The cohesin protein complex was first recognized for holding sister chromatids together and ensuring proper chromosome segregation. Cohesin also regulates gene expression, but the mechanisms are unknown. Cohesin associates preferentially with active
Externí odkaz:
https://doaj.org/article/199cb84bcf8944dbb1f2cbbd80bbbd81
Cohesin consists of the SMC1-SMC3-Rad21 tripartite ring and the SA protein that interacts with Rad21. The Nipped-B protein loads cohesin topologically around chromosomes to mediate sister chromatid cohesion and facilitate long-range control of gene t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff42e747bb20586ba7ed4aac78a601eb
https://doi.org/10.1101/539270
https://doi.org/10.1101/539270
Autor:
Courtney A. Iberg, Ian Fallahee, Daniel Hawiger, Dale Dorsett, Jessica Bourque, Adeleye Opejin, Cindy Gross, Alexey Surnov, Ziva Misulovin, Michelle Pherson
Publikováno v:
Cell Reports. 33:108424
Summary Various processes induce and maintain immune tolerance, but effector T cells still arise under minimal perturbations of homeostasis through unclear mechanisms. We report that, contrary to the model postulating primarily tolerogenic mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4115f8005e90b441ab4dc089911ac028
https://doi.org/10.1016/j.celrep.2020.108424
https://doi.org/10.1016/j.celrep.2020.108424
Autor:
Joy Samanich, Karen W. Gripp, Zhe Zhang, Julian L. Allen, Masashige Bando, Matthew A. Deardorff, Maninder Kaur, Katsuhiko Shirahige, Matthew C. Dulik, Ian D. Krantz, Kosuke Izumi, Dale Dorsett, Ryuichiro Nakato, Andrew C. Edmondson, Sarah E. Noon, Makiko Komata, Elaine H. Zackai, Charles P. Venditti, Ramkakrishnan Rajagopalan, Dinah Clark, Ziva Misulovin, Yuki Katou
Publikováno v:
Nature genetics
Transcriptional elongation is critical for gene expression regulation during embryogenesis. The super elongation complex (SEC) governs this process by mobilizing paused RNA polymerase II (RNAP2). Using exome sequencing, we discovered missense mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f204ea8484eee0f0d8bb182428da079
http://europepmc.org/articles/PMC4380798
http://europepmc.org/articles/PMC4380798