Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ziv Machnes"'
Autor:
Amanda Long, Ikuo Yamamiya, Michelle Valentine, Ziv Machnes, Nanae Hangai, Bailey Anderson, Volker Wacheck, Ling Gao
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 9, Pp n/a-n/a (2024)
Abstract Futibatinib, an inhibitor of fibroblast growth factor receptor 1–4, is approved for the treatment of patients with advanced cholangiocarcinoma with FGFR2 fusions/rearrangements. In this phase I drug–drug interaction study, the effects of
Externí odkaz:
https://doaj.org/article/bfe265f2afa54fc88a994fbc5301cf02
Autor:
Lei Cao-Lei, Renaud Massart, Matthew J Suderman, Ziv Machnes, Guillaume Elgbeili, David P Laplante, Moshe Szyf, Suzanne King
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107653 (2014)
Prenatal maternal stress (PNMS) predicts a wide variety of behavioral and physical outcomes in the offspring. Although epigenetic processes may be responsible for PNMS effects, human research is hampered by the lack of experimental methods that paral
Externí odkaz:
https://doaj.org/article/4696407cca3348f2a272353fc290f5e8
Autor:
Moshe Szyf, Avishag Metzer, Abraham Haim, Fuad Fares, Yonit Pilosof, Ziv Machnes, Hagit Schwimmer, Orna Harel
Publikováno v:
Chronobiology International. 31:144-150
Light-at-night (LAN) is a worldwide problem co-distributed with breast cancer prevalence. We hypothesized that exposure to LAN is coincided with a decreased melatonin (MLT) secretion level, followed by epigenetic modifications and resulted in higher
Autor:
Matthew Suderman, Ziv Machnes, Barbara Stefanska, Michael Hallett, Bishnu Bhattacharyya, Moshe Szyf
Publikováno v:
Carcinogenesis. 34:2738-2749
We previously delineated genes whose promoters are hypomethylated and induced in hepatocellular carcinoma (HCC) patients. The purpose of this study was to establish the players that regulate these genes in liver cancer cells. We performed chromatin i
Autor:
A. Claudio Cuello, Marie L. Jacobs, Lei Yu, Moshe Szyf, Adriana Ducatenzeiler, Ziv Machnes, Jingyun Yang, Edward N. Wilson, David A. Bennett, M. Florencia Iulita, Sonia Do Carmo
Publikováno v:
Alzheimer's & Dementia. 12
Autor:
Suzanne King, Guillaume Elgbeili, David P. Laplante, Moshe Szyf, Ziv Machnes, Lei Cao-Lei, Matthew Suderman, Renaud Massart
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 9, p e107653 (2014)
PLoS ONE, Vol 9, Iss 9, p e107653 (2014)
Background Prenatal maternal stress (PNMS) predicts a wide variety of behavioral and physical outcomes in the offspring. Although epigenetic processes may be responsible for PNMS effects, human research is hampered by the lack of experimental methods
Publikováno v:
Carcinogenesis. 35(1)
DNA-demethylating agents activate tumor suppressor genes that are silenced by DNA methylation in cancer and are therefore emerging as a novel approach to cancer therapy. 5-azacytidine (VIDAZA), the first representative of this class of drugs was appr
Autor:
Terence J. O'Brien, Moshe Szyf, Nigel C. Jones, Nicholas Reist, Ziv Machnes, Philip K.-Y. Chang, Francois Charron, Ezgi Ozturk, R. Anne McKinney, Gabriella Dezsi, Tony Chieh-Ting Huang, Raminder Gill
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76299 (2013)
PLoS ONE
PLoS ONE
Epilepsy is a chronic brain disorder involving recurring seizures often precipitated by an earlier neuronal insult. The mechanisms that link the transient neuronal insult to the lasting state of epilepsy are unknown. Here we tested the possible role
Autor:
Vasilis G. Moisiadis, Sophie Petropoulos, Stephen G. Matthews, Ariann Crudo, Moshe Szyf, Alisa Kostaki, Ziv Machnes, Majid Iqbal
Publikováno v:
Endocrinology
Prenatal synthetic glucocorticoids (sGC) are administered to pregnant women at risk of delivering preterm, approximately 10% of all pregnancies. Animal studies have demonstrated that offspring exposed to elevated glucocorticoids, either by administra
Autor:
Andrey Shirak, David Trombka, Jeremy Don, Ron Wides, Ziv Machnes, Marc Fellous, Ramy R. Avtalion
Publikováno v:
Hormones and behavior. 54(3)
MSP is a male-specific protein initially identified in the serum of sexually active Sarotherodon galilaeus males, and is shown herein to be present in the serum of sexually mature males, but not females, of three other tilapia species. Cloning of the