Targeted donor complement blockade after brain death prevents delayed graft function in a nonhuman primate model of kidney transplantation.

Autor: Danobeitia JS; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Zens TJ; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Chlebeck PJ; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Zitur LJ; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Reyes JA; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Eerhart MJ; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Coonen J; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA., Capuano S; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA., D'Alessandro AM; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Torrealba JR; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Burguete D; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Brunner K; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA., Van Amersfoort E; Pharming Technologies B.V., Leiden, the Netherlands., Ponstein Y; Pharming Technologies B.V., Leiden, the Netherlands., Van Kooten C; Department of Nephrology, Leiden University Medical Center, Leiden, the Netherlands., Jankowska-Gan E; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Burlingham W; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Sullivan J; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Djamali A; Department of Medicine, Division of Nephrology, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Pozniak M; Department of Radiology, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Yankol Y; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA., Fernandez LA; Department of Surgery, Division of Transplantation, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin, USA.

Publikováno v: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2020 Jun; Vol. 20 (6), pp. 1513-1526. Date of Electronic Publication: 2020 Feb 20.

Brain Death Enhances Activation of the Innate Immune System and Leads to Reduced Renal Metabolic Gene Expression.

Autor: Zitur LJ; Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI., Chlebeck PJ; Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI., Odorico SK; Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI., Danobeitia JS; Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI., Zens TJ; Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI., Van Kooten C; Department of Nephrology, Leiden University Medical Centre, Leiden, Netherlands., Eerhart M; Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI., Reyes JA; Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI., Springer ML; Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI., Coonen JM; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI., Brunner KG; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI., Capuano SV; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI., D'Alessandro AM; Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI., Fernandez LA; Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Publikováno v: Transplantation [Transplantation] 2019 Sep; Vol. 103 (9), pp. 1821-1833.

Guidelines for the management of a brain death donor in the rhesus macaque: A translational transplant model.

Autor: Zens TJ; University of Wisconsin Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America., Danobeitia JS; University of Wisconsin Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America., Chlebeck PJ; University of Wisconsin Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America., Zitur LJ; University of Wisconsin Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America., Odorico S; University of Wisconsin Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America., Brunner K; Wisconsin Primate Research Center, University of Wisconsin, Madison, Wisconsin, United States of America., Coonen J; Wisconsin Primate Research Center, University of Wisconsin, Madison, Wisconsin, United States of America., Capuano S; Wisconsin Primate Research Center, University of Wisconsin, Madison, Wisconsin, United States of America., D'Alessandro AM; University of Wisconsin Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America., Matkowskyj K; University of Wisconsin Department of Pathology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America., Zhong W; University of Wisconsin Department of Pathology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America., Torrealba J; University of Texas Southwestern Medical Center Department of Pathology, Dallas, Texas, United States of America., Fernandez L; University of Wisconsin Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.

Publikováno v: PloS one [PLoS One] 2017 Sep 19; Vol. 12 (9), pp. e0182552. Date of Electronic Publication: 2017 Sep 19 (Print Publication: 2017).

Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion.

Autor: Ansari IH; Childrens Diabetes Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, United States., Longacre MJ; Childrens Diabetes Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, United States., Stoker SW; Childrens Diabetes Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, United States., Kendrick MA; Childrens Diabetes Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, United States., O'Neill LM; Department of Biochemistry, University of Wisconsin, Madison, WI 53706, United States., Zitur LJ; Department of Surgery, Division of Organ Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, United States., Fernandez LA; Department of Surgery, Division of Organ Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, United States., Ntambi JM; Department of Biochemistry, University of Wisconsin, Madison, WI 53706, United States., MacDonald MJ; Childrens Diabetes Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, United States. Electronic address: mjmacdon@wisc.edu.

Publikováno v: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2017 Mar 15; Vol. 618, pp. 32-43. Date of Electronic Publication: 2017 Feb 11.

Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells.

Autor: Dejosez M; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, USA., Krumenacker JS, Zitur LJ, Passeri M, Chu LF, Songyang Z, Thomson JA, Zwaka TP

Publikováno v: Cell [Cell] 2008 Jun 27; Vol. 133 (7), pp. 1162-74.