Mechanics of lung cancer: A finite element model shows strain amplification during early tumorigenesis.

Autor: Zitnay, Rebecca G.^1,2 (AUTHOR), Herron, Michael R.¹ (AUTHOR), Carney, Keith R.³ (AUTHOR), Potter, Scott^2,4 (AUTHOR), Emerson, Lyska L.^2,4 (AUTHOR), Weiss, Jeffrey A.^1,5 (AUTHOR) Jeff.Weiss@utah.edu, Mendoza, Michelle C.^1,2,3 (AUTHOR) Jeff.Weiss@utah.edu

Publikováno v: PLoS Computational Biology. 10/24/2022, Vol. 18 Issue 10, p1-22. 22p. 3 Color Photographs, 3 Diagrams, 2 Charts.

Tenascin-C in the early lung cancer tumor microenvironment promotes progression through integrin αvβ1 and FAK.

Autor: Samson SC; Department of Oncological Sciences, University of Utah, Salt Lake City, UT 84112.; Huntsman Cancer Institute, Salt Lake City, UT 84112., Rojas A; Department of Oncological Sciences, University of Utah, Salt Lake City, UT 84112.; Huntsman Cancer Institute, Salt Lake City, UT 84112., Zitnay RG; Huntsman Cancer Institute, Salt Lake City, UT 84112.; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT 84112., Carney KR; Department of Oncological Sciences, University of Utah, Salt Lake City, UT 84112.; Huntsman Cancer Institute, Salt Lake City, UT 84112., Hettinga W; Huntsman Cancer Institute, Salt Lake City, UT 84112.; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT 84112., Schaelling MC; Department of Oncological Sciences, University of Utah, Salt Lake City, UT 84112.; Huntsman Cancer Institute, Salt Lake City, UT 84112., Sicard D; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905., Zhang W; Huntsman Cancer Institute, Salt Lake City, UT 84112.; Department of Pathology, University of Utah, Salt Lake City, UT 84112., Gilbert-Ross M; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA 30322., Dy GK; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203., Cavnar MJ; Department of Surgery, University of Kentucky, Lexington, KY 40508., Furqan M; Department of Internal Medicine, University of Iowa Health Care, Iowa City, IA 52246., Browning RF Jr; Department of Medicine, Walter Reed National Military Medical Center, Bethesda, MD 20889., Naqash AR; Division of Medical Oncology, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104., Schneider BP; Department of Hematology and Oncology, Indiana University School of Medicine, Indianapolis, IN 46202., Tarhini A; Departments of Cutaneous Oncology and Immunology, H. Lee Moffit Cancer Center & Research Institute, Tampa, FL 33612., Tschumperlin DJ; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905., Venosa A; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84112., Marcus AI; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA 30322.; Long Island University, College of Veterinary Medicine, Brookville, NY 11548., Emerson LL; Huntsman Cancer Institute, Salt Lake City, UT 84112.; Department of Pathology, University of Utah, Salt Lake City, UT 84112., Spike BT; Department of Oncological Sciences, University of Utah, Salt Lake City, UT 84112.; Huntsman Cancer Institute, Salt Lake City, UT 84112., Knudsen BS; Huntsman Cancer Institute, Salt Lake City, UT 84112.; Department of Pathology, University of Utah, Salt Lake City, UT 84112., Mendoza MC; Department of Oncological Sciences, University of Utah, Salt Lake City, UT 84112.; Huntsman Cancer Institute, Salt Lake City, UT 84112.; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT 84112.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 21. Date of Electronic Publication: 2024 Sep 21.