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pro vyhledávání: '"Zitha R. Isingizwe"'
Autor:
Benjamin E. Tourdot, Reheman Adili, Zitha R. Isingizwe, Meral Ebrahem, J. Cody Freedman, Theodore R. Holman, Michael Holinstat
Publikováno v:
Blood Advances, Vol 1, Iss 15, Pp 1124-1131 (2017)
Abstract: The dihomo-γ-linolenic acid (DGLA)–derived metabolite of 12-lipoxygenase, 12-hydroxy-eicosatrienoic acid (12-HETrE), was recently shown to potently inhibit thrombus formation without prolonging bleeding in murine models. Although 12-HETr
Externí odkaz:
https://doaj.org/article/0216b0e948b94426ad8530ece9a0043b
Publikováno v:
Blood. 128:714-714
Platelet activation is a critical component of clot formation. Under pathophysiological conditions platelet-mediated clot formation can lead to an occlusive thrombotic event resulting in myocardial infarction and stroke. Regulation of platelet reacti