Preliminary Investigation of the Antibacterial Activity of Antitumor Drug 3-Amino-1,2,4-Benzotriazine-1,4-Dioxide (Tirapazamine) and its Derivatives

Autor: Evelina Polmickaitė-Smirnova, Jonas Šarlauskas, Kastis Krikštopaitis, Živilė Lukšienė, Zita Staniulytė, Žilvinas Anusevičius

Publikováno v: Applied Sciences, Vol 10, Iss 12, p 4062 (2020)

The antitumor drug 3-amino-1,2,4-benzotriazine-1,4-dioxide (tirapazamine, TPZ (1)) along with a number of newly synthesized tirapazamine derivatives (TPZs) bearing substitutions at the 3-amine position of TPZ (1) were estimated for their antibacteria

Externí odkaz: https://doaj.org/article/00b6d7faf6014048b796cdbce74ee316

Preliminary investigation of the antibacterial activity of antitumor drug 3-amino-1,2,4-benzotriazine-1,4-dioxide (tirapazamine) and its derivatives

Autor: Jonas Šarlauskas, Evelina Polmickaitė-Smirnova, Živilė Lukšienė, Žilvinas Anusevičius, Zita Staniulytė, Kastis Krikštopaitis

Publikováno v: Applied sciences, Basel : MDPI, 2020, vol. 10, iss. 12, art. no. 4062, p. [1-15]
Applied Sciences, Vol 10, Iss 4062, p 4062 (2020)
Applied Sciences
Volume 10
Issue 12

The antitumor drug 3-amino-1,2,4-benzotriazine-1,4-dioxide (tirapazamine, TPZ (1)) along with a number of newly synthesized tirapazamine derivatives (TPZs) bearing substitutions at the 3-amine position of TPZ (1) were estimated for their antibacteria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744a66fa628c51d8a5c846bdc27467ad
https://repository.vu.lt/VU:ELABAPDB80577691&prefLang=en_US

New 1-(3-nitrophenyl)-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepines: synthesis and computational study

Autor: Romualdas Sirutkaitis, Zita Staniulytė, Algirdas Palaima, Antanas Karalius, Žilvinas Anusevičius, Lidija Kosychova, Audrius Laurynėnas

Publikováno v: Molecules
Volume 20
Issue 4
Pages 5392-5408
Molecules, Vol 20, Iss 4, Pp 5392-5408 (2015)
Molecules, Basel : MDPIAG, 2015, Vol. 20, no. 4, p. 5392-5408
Molecules, Basel : MDPI, 2015, vol. 20, no. 4, p. 5392-5408

Triazole derivatives constitute an important group of heterocyclic compounds have have been the subject of extensive study in the recent past. These compounds have shown a wide range of biological and pharmacological activities. In this work, new fus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2d0dd15ab095b1b76f2281d9be8245
https://pubmed.ncbi.nlm.nih.gov/25822079

Preliminary Investigation of the Antibacterial Activity of Antitumor Drug 3-Amino-1,2,4-Benzotriazine-1,4-Dioxide (Tirapazamine) and its Derivatives.

Autor: Polmickaitė-Smirnova, Evelina, Šarlauskas, Jonas, Krikštopaitis, Kastis, Lukšienė, Živilė, Staniulytė, Zita, Anusevičius, Žilvinas

Publikováno v: Applied Sciences (2076-3417); 6/15/2020, Vol. 10 Issue 12, p4062, 15p