Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Zita, Balklava"'
Autor:
Suhayl Mulla, Adele R. Ludlam, Aiman Elragig, Cathy Slack, Zita Balklava, Michael Stich, Alex Cheong
Publikováno v:
Royal Society Open Science, Vol 10, Iss 2 (2023)
Ageing research focuses on identifying lifespan modifiers and understanding and appropriately interpreting their effects. One of the most relevant quantities being studied is the shape of the survival curve that can reveal crucial information on the
Externí odkaz:
https://doaj.org/article/ba67b3d7508d4eb1905a6c215ea6dc08
Autor:
Natalya Vodolazkaya, Marina Nikolskaya, Anna Laguta, Vladimir Farafonov, Zita Balklava, Michael Stich, Nikolay Mchedlov-Petrossyan, Dmitry Nerukh
Publikováno v:
The journal of physical chemistry. B. 126(41)
MS2 bacteriophage is often used as a model for evaluating pathogenic viruses' behavior in aqueous solution. However, the questions of the virus surface's hydrophilic/hydrophobic balance, the charge distribution, and the binding mechanism are open. Us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7f2bd1391a7a5ef96c1e1c7f4c7667
https://pubmed.ncbi.nlm.nih.gov/36198175
https://pubmed.ncbi.nlm.nih.gov/36198175
Autor:
Andrea Markou, Lucas Unger, Mohammed Abir-Awan, Ahmed Saadallah, Andrea Halsey, Zita Balklava, Matthew Conner, Susanna Törnroth-Horsefield, Stuart D. Greenhill, Alex Conner, Roslyn M. Bill, Mootaz M. Salman, Philip Kitchen
The aquaporins (AQPs) form a family of integral membrane proteins that facilitate the movement of water across biological membrane by osmosis, as well as facilitating the diffusion of small polar solutes. AQPs have been recognised as drug targets for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6225e190153f210863c0e8be13b43d06
https://publications.aston.ac.uk/id/eprint/43431/1/1_s2.0_S0005273621003011_main.pdf
https://publications.aston.ac.uk/id/eprint/43431/1/1_s2.0_S0005273621003011_main.pdf
Autor:
Zita Balklava, Christian Niehage, Heather Currinn, Laura Mellor, Benjamin Guscott, Gino Poulin, Bernard Hoflack, Thomas Wassmer
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130485 (2015)
While the Amyloid Precursor Protein (APP) plays a central role in Alzheimer's disease, its cellular function still remains largely unclear. It was our goal to establish APP function which will provide insights into APP's implication in Alzheimer's di
Externí odkaz:
https://doaj.org/article/37a975215e6641dea43cf0d7be01a434
Autor:
Valeriya Trusova, Nikolay O. Mchedlov-Petrossyan, Galyna Gorbenko, Olga Zhytniakivska, Nikolai Gadjev, Kateryna Vus, Uliana Tarabara, Anna N. Laguta, Vladimir Farafonov, Dmitry Nerukh, Todor Deligeorgiev, Nika N. Kriklya, Michael Stich, Zita Balklava, Atanas Kurutos, N. A. Vodolazkaya
Novel monomethine cyanine dyes Cl-YO, F-YO, Cl-YO-Et, Cl-YO-Bu, and YO-Pent were evaluated as agents to detect and characterise a small virus, the MS2 bacteriophage, using the dye and virus intrinsic fluorescence, kinetic and thermal properties, chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d71937bcccb92dcd8a60e90123e5df1
https://publications.aston.ac.uk/id/eprint/41159/1/Manuscript_Vus_JML_MS2_capsid_binding.pdf
https://publications.aston.ac.uk/id/eprint/41159/1/Manuscript_Vus_JML_MS2_capsid_binding.pdf
Autor:
Zita Balklava, Saumya Pant, Carlos Chih Hsiung Chen, Vanesa Figueroa, Barth D. Grant, Anbing Shi
Publikováno v:
Current Biology. 17:1913-1924
BACKGROUND: Alix/Bro1p family proteins have recently been identified as important components of multivesicular endosomes (MVEs) and are involved in the sorting of endocytosed integral membrane proteins, interacting with components of the ESCRT comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4a358e50768c8ee96a2f23e763b709
https://doi.org/10.1016/j.cub.2007.10.045
https://doi.org/10.1016/j.cub.2007.10.045
Publikováno v:
Nature Cell Biology. 9:1066-1073
In a genome-wide RNA-mediated interference screen for genes required in membrane traffic - including endocytic uptake, recycling from endosomes to the plasma membrane, and secretion - we identified 168 candidate endocytosis regulators and 100 candida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374e7d254ad51b8a2c1eb31528735568
https://doi.org/10.1038/ncb1627
https://doi.org/10.1038/ncb1627
Publikováno v:
Bioscience Reports
In this work we developed and validated a cell permeable tool to study the intracellular function of a central molecule in Alzheimer's disease, the amyloid precursor protein. We showed that it regulates the activity of the PIKfyve kinase complex.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce642564061120e97d23605b765384f
https://pubmed.ncbi.nlm.nih.gov/26934981
https://pubmed.ncbi.nlm.nih.gov/26934981
Autor:
Heather Currinn, Laura E. Mellor, Benjamin Guscott, Bernard Hoflack, Christian Niehage, Zita Balklava, Gino B. Poulin, Thomas Wassmer
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130485 (2015)
PLoS ONE
PLoS ONE
While the Amyloid Precursor Protein (APP) plays a central role in Alzheimer's disease, its cellular function still remains largely unclear. It was our goal to establish APP function which will provide insights into APP's implication in Alzheimer's di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6328697aa47810cef02fcf32897ba8d
https://publications.aston.ac.uk/id/eprint/26188/1/Amyloid_precursor_protein_controls_PIKfyve_function.pdf
https://publications.aston.ac.uk/id/eprint/26188/1/Amyloid_precursor_protein_controls_PIKfyve_function.pdf
Publikováno v:
Journal of Investigative Dermatology. 121(2):412-423
Investigations were undertaken to study the role of the protein cross-linking enzyme tissue transglutaminase in changes associated with the extracellular matrix and in the cell death of human dermal fibroblasts following exposure to a solarium ultrav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5063e6ea800240d40992938d7b812ef