Výsledky vyhledávání - "Zissis Chroneos"

Akademický článek

Macrophage Functions and Regulation: Roles in Diseases and Implications in Therapeutics

Autor: Kebin Hu, Yang Jin, Zissis Chroneos, Xiaodong Han, Hao Liu, Ling Lin

Publikováno v: Journal of Immunology Research, Vol 2018 (2018)

Externí odkaz: https://doaj.org/article/52afa6a73e0649658982b48eeac532be

Disruption of the surfactant protein A receptor isoform SP-R210L in alveolar macrophages alters airway, vascular, and immune homeostasis in the lung

Autor: Zissis Chroneos, Todd Umstead

Publikováno v: Physiology. 38

Surfactant protein A modulates alveolar macrophage activation and pathogen clearance through the receptor SP-R210, which consists of a homeostatic SP-R210L and an inflammatory SP-R210S isoform in alveolar macrophages (AMs). Both isoforms are encoded

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c969df42c2f0a7903e1d4dbf26af717d
https://doi.org/10.1152/physiol.2023.38.s1.5794477

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Interleukin-4 Enhances Pulmonary Clearance ofPseudomonas aeruginosa

Autor: Shilpa Jain-Vora, Ann Marie LeVine, Zissis Chroneos, Gary F. Ross, William M. Hull, Jeffrey A. Whitsett

Publikováno v: Infection and Immunity. 66:4229-4236

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d967cdd6405fa6c1442be4ff94342638
https://doi.org/10.1128/.66.9.4229-4236.1998

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Influenza induces GM-CSF deficiency: lung-specific overexpression after infection confers protection (INC1P.355)

Autor: Eric Halstead, Weichao Guo, Linlin Yang, Sanmei Hu, Todd Umstead, Kevan Hartshorn, Mitch White, Zissis Chroneos

Publikováno v: The Journal of Immunology. 194:54.12-54.12

GM-CSF is an essential cytokine for normal lung immune homeostasis. In the current studies we examined the role of GM-CSF and its lung-specific conditional overexpression on the host immune response to influenza. Transgenic tet-GM+/+ mice were intran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d2465e7f77c4d4b643adbe156e098c8
https://doi.org/10.4049/jimmunol.194.supp.54.12

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Phosphoinositide-3-kinase p110δ isoform promotes influenza pathogenicity (MUC5P.858)

Autor: Aidan Hancock, Alina Boesteanu, Zissis Chroneos, Martin Turner, Peter Katsikis

Publikováno v: The Journal of Immunology. 192:134.1-134.1

We have found that mice deficient in a tissue specific isoform of the signaling enzyme phosphoinositide-3 kinase (PI3K) p110δ are protected from PR8 influenza virus infection and have reduced weight loss and lung viral loads post-infection. Lung inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be7ef3411c5ee9e77264f7e5dcdd6dfa
https://doi.org/10.4049/jimmunol.192.supp.134.1

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Targeting of the surfactant protein A receptor SP-R210L variant by influenza A virus in macrophages. (INM8P.440)

Autor: Linlin Yang, Sanmei Hu, Zissis Chroneos

Publikováno v: The Journal of Immunology. 192:124.6-124.6

Alveolar macrophages (AM) are critical for controlling IAV infection by limiting virus release and by initiating innate and adaptive immunity. Surfactant proteins A (SP-A) and D (SP-D) are a primary line of defense against IAV. Previous studies demon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::962bced519954434447b1bc125939ce0
https://doi.org/10.4049/jimmunol.192.supp.124.6

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