Understanding the rod-to-tube transformation of self-assembled ascorbyl dipalmitate lipid nanoparticles stabilized with PEGylated lipids

Autor: Ziqiao Chen, Kenjirou Higashi, Yuki Shigehisa, Keisuke Ueda, Keiji Yamamoto, Kunikazu Moribe

Publikováno v: Nanoscale.

We previously established a nanoparticle-based drug delivery system (DDS) for high-dose ascorbic acid therapy by self-assembly of a lipid-modified ascorbic acid derivative, L-ascorbyl 2,6-dipalmitate (ASC-DP). The particles' morphology should be modi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2108852acd48f5d302963423cd26e20
https://pubmed.ncbi.nlm.nih.gov/36484313

Multistep Crystallization of Pharmaceutical Amorphous Nanoparticles via a Cognate Pathway of Oriented Attachment: Direct Evidence of Nonclassical Crystallization for Organic Molecules

Autor: Ziqiao Chen, Kenjirou Higashi, Keisuke Ueda, Kunikazu Moribe

Publikováno v: Nano letters. 22(16)

Crystallization of organic molecules is important in a wide range of scientific disciplines. However, in contrast to maturely studied crystallization of inorganic materials, the crystallization mechanisms of organic molecules involving nucleation and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e072a86cc93c44cb0fb3989777793a8c
https://pubmed.ncbi.nlm.nih.gov/35830610

Transition from Amorphous Cyclosporin A Nanoparticles to Size-Reduced Stable Nanocrystals in a Poloxamer 407 Solution

Autor: Kenjirou Higashi, Keisuke Ueda, Ziqiao Chen, Kunikazu Moribe

Publikováno v: Molecular pharmaceutics. 19(1)

Amorphous drug nanoparticles usually exhibit low storage stability. A comprehensive understanding of the molecular states and physicochemical properties of the product is indispensable for designing stable formulations. In the present study, an amorp

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https://pubmed.ncbi.nlm.nih.gov/34843257

Applying Policy Process Theories to Environmental Governance Research: Themes and New Directions

Autor: Tatyana B. Ruseva, Megan Foster, Ziqiao Chen, Riley Pudney, Abigail M. York, Gwen Arnold, Saba Siddiki

Publikováno v: Policy Studies Journal. 47:S66-S95

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9603450b6e21a673ac67a38dc62b850d
https://doi.org/10.1111/psj.12317

Green Stimulus in a Post-pandemic Recovery: the Role of Skills for a Resilient Recovery

Autor: Ziqiao Chen, Francesco Vona, David Popp, Giovanni Marin

Publikováno v: Environmental and Resource Economics
Environmental & Resource Economics
Environmental and Resource Economics, 76, 902-911 (2020)
Environmental and Resource Economics, 2020, 76, pp.902-911. ⟨10.1007/s10640-020-00464-7⟩

As nations struggle to restart their economy after COVID-19 lockdowns, calls to include green investments in a pandemic-related stimulus are growing. Yet little research provides evidence of the effectiveness of a green stimulus. We begin by summariz

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