Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ziqiang Ding"'
Autor:
Shenxia Xie, Wei Shi, Siliang Duan, Xianing Huang, Aiqun Liu, Xiaoqiong Hou, Xuandong Lin, Dani Zhong, Shuyang Sun, Ziqiang Ding, Xiaomei Yang, Xiaoyuan Chen, Xiaoling Lu
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background T cell-based immunotherapies are facing great challenges in the recruitment and activation of tumor-specific T cells against solid tumors. Among which, utilizing nanobody (Nb) or nanobodies (Nbs) to construct T cell engager has em
Externí odkaz:
https://doaj.org/article/34819bd0e84d4974b541afced7e0be7f
Autor:
Liyan Hu, Xingdong Wang, Shaoke Guo, Mengli Cao, Yandong Kang, Ziqiang Ding, Jie Pei, Qianyun Ge, Yi Ma, Xian Guo
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background The Testis is an important reproductive organ in male mammals and the site for spermatogenesis, androgen synthesis, and secretion. Non-coding RNAs (ncRNAs) play an important regulatory role in various biological processes. However
Externí odkaz:
https://doaj.org/article/951ef957426d47888d91adf58928fb7d
Autor:
Jie Pei, Lin Xiong, Xingdong Wang, Shaoke Guo, Mengli Cao, Ziqiang Ding, Yandong Kang, Min Chu, Xiaoyun Wu, Pengjia Bao, Xian Guo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Yaks (Bos grunniens) exhibit exceptional adaptation to the challenging high-altitude environment of the Qinghai-Tibetan plateau, making them the sole bovine species capable of thriving in such exreme conditions. Investigating the cellular and molecul
Externí odkaz:
https://doaj.org/article/cd6a0fed067645149d7b96d0b64578f7
Autor:
Ziqiang Ding, Shuyang Sun, Xuan Wang, Xiaomei Yang, Wei Shi, Xianing Huang, Shenxia Xie, Fengzhen Mo, Xiaoqiong Hou, Aiqun Liu, Xiaobing Jiang, Zhuoran Tang, Xiaoling Lu
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-20 (2023)
Abstract Background T cell engagers (TCEs) have been established as an emerging modality for hematologic malignancies, but solid tumors remain refractory. However, the upregulation of programmed cell death 1 (PD-1) is correlated with T cell dysfuncti
Externí odkaz:
https://doaj.org/article/d7cf21ab350043c3a55e1d6c78ecd683
Autor:
Ben Zhang, Mengli Cao, Xingdong Wang, Shaoke Guo, Ziqiang Ding, Yandong Kang, Liyan Hu, Lin Xiong, Jie Pei, Yi Ma, Xian Guo
Publikováno v:
Foods, Vol 13, Iss 15, p 2364 (2024)
In order to investigate the composition and differences in volatile organic compounds (VOCs) in yak and cattle-yak meat and determine the key metabolites and metabolic pathways related to flavor formation. In this study, the VOCs and non-volatile met
Externí odkaz:
https://doaj.org/article/24ff27fb412541aead3433b6d2eb074f
Autor:
Shaoke Guo, Jie Pei, Xingdong Wang, Mengli Cao, Lin Xiong, Yandong Kang, Ziqiang Ding, Yongfu La, Min Chu, Pengjia Bao, Xian Guo
Publikováno v:
Animals, Vol 13, Iss 18, p 2815 (2023)
Studying the mechanism of spermatogenesis is key to exploring the reproductive characteristics of male yaks. Although N6-methyladenosine (m6A) RNA modification has been reported to regulate spermatogenesis and reproductive function in mammals, the mo
Externí odkaz:
https://doaj.org/article/8f593a62d972451e81bdd31b2cda278a
Autor:
Haixia Li, Dani Zhong, Huiguan Luo, Wei Shi, Shenxia Xie, Hangbiao Qiang, Lichen Zhu, Li Gao, Jun Liu, Shuyang Sun, Ziqiang Ding, Xiaomei Yang, Xiaoling Lu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113919- (2022)
Chimeric antigen receptor (CAR) T-cell immunotherapy has become one of the research hotspots in the treatment of malignant tumors nowadays. However, the available tumor surface antigens are limited in number. Most tumor-associated antigens are intrac
Externí odkaz:
https://doaj.org/article/231c0e07cf034f2599f12622f02125a2
Autor:
Xingdong Wang, Jie Pei, Lin Xiong, Shaoke Guo, Mengli Cao, Yandong Kang, Ziqiang Ding, Yongfu La, Chunnian Liang, Ping Yan, Xian Guo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7982 (2023)
Spermatogenesis is a complex process that involves proliferation and differentiation of diploid male germ cells into haploid flagellated sperm and requires intricate interactions between testicular somatic cells and germ cells. The cellular heterogen
Externí odkaz:
https://doaj.org/article/848a5f1bb15f4a16b0eb18d0dd7cacd4
Autor:
Ziqiang Ding, Lin Xiong, Xingdong Wang, Shaoke Guo, Mengli Cao, Yandong Kang, Yongfu La, Pengjia Bao, Jie Pei, Xian Guo
Publikováno v:
Animals, Vol 13, Iss 8, p 1355 (2023)
Epididymis development is the basis of male reproduction and is a crucial site where sperm maturation occurs. In order to further understand the epididymal development of yak and how to regulate sperm maturation, we conducted a multi-omics analysis.
Externí odkaz:
https://doaj.org/article/bda984cd0f6a49e6abc0ae62ce5260ce
Autor:
Fengzhen Mo, Siliang Duan, Xiaobing Jiang, Xiaomei Yang, Xiaoqiong Hou, Wei Shi, Cueva Jumbo Juan Carlos, Aiqun Liu, Shihua Yin, Wu Wang, Hua Yao, Zihang Yu, Zhuoran Tang, Shenxia Xie, Ziqiang Ding, Xinyue Zhao, Bruce D. Hammock, Xiaoling Lu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Chimeric antigen receptor-based T-cell immunotherapy is a promising strategy for treatment of hematological malignant tumors; however, its efficacy towards solid cancer remains challenging. We therefore focused on developing nanobody-based C
Externí odkaz:
https://doaj.org/article/0467899002724f14b4216f34d0b7aa35