Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Zippora, Lupowitz"'
Publikováno v:
Molecular and Cellular Endocrinology. 252:82-87
Melatonin induces nuclear exclusion of the androgen receptor (AR) via activation of protein kinase C (PKC). The specific members of the PKC superfamily involved in AR nuclear exclusion were investigated in prostate cancer PC3 cells stably transfected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d91498b70b55a66d1534ef9fe75ba7
https://doi.org/10.1016/j.mce.2006.03.033
https://doi.org/10.1016/j.mce.2006.03.033
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 81:77-84
Androgen receptors (AR) play a crucial role in androgen-mediated processes and prostate cancer progression. The pineal hormone melatonin attenuates the androgen-dependent growth of benign and cancer prostate epithelial cells in vitro and may reverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dd0680a2e85e285f352a3d511ec9f5
https://doi.org/10.1016/s0960-0760(02)00050-x
https://doi.org/10.1016/s0960-0760(02)00050-x
Publikováno v:
Journal of pineal research. 40(2)
Regulators of G protein signaling (RGS) are proteins that bind specifically to activated Galpha subunits of heterotrimeric G proteins to terminate signaling by both Galpha and Gbetagamma subunits. Signal-induced RGS redistribution may affect their ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b85458be1e1364a8b46dd48722ac5f
https://pubmed.ncbi.nlm.nih.gov/16441551
https://pubmed.ncbi.nlm.nih.gov/16441551
Publikováno v:
Cellular and molecular life sciences : CMLS. 58(14)
The intracellular signaling pathways mediating the nuclear exclusion of the androgen receptor (AR) by melatonin were evaluated in PC3 cells stably transfected with the AR. The melatonin-induced nuclear exclusion of the AR by melatonin (100 nM, 3 h) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf4228c6dc35b6f9848db22d752363d
https://pubmed.ncbi.nlm.nih.gov/11814062
https://pubmed.ncbi.nlm.nih.gov/11814062
Autor:
Zippora Lupowitz, Zoran Culig, Georg Bartsch, Nava Zisapel, Galit Levy-Rimler, Avi Rimler, Helmut Klocker, Haim Matzkin
Publikováno v:
The Prostate. 49(2)
Background The androgen receptor (AR) promotes growth and functionality of androgen sensitive benign and cancer tissues. The pineal hormone melatonin is an androgen protagonist in vivo and in vitro. The interference of melatonin in the AR cascade was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1598e7f6b72fb5ddc00290bb4ab47d
https://pubmed.ncbi.nlm.nih.gov/11582594
https://pubmed.ncbi.nlm.nih.gov/11582594
Publikováno v:
Neuro endocrinology letters. 23
The pineal hormone melatonin inhibits the growth of benign human prostate epithelial cells and the androgen-dependent prostate cancer LNCaP cells. In the androgen-nonresponsive prostate carcinoma PC3 cells melatonin inhibits cell growth only at high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50cc53551e169d592620e04a077c1d5d
https://pubmed.ncbi.nlm.nih.gov/12019351
https://pubmed.ncbi.nlm.nih.gov/12019351
Autor:
Nava Zisapel, Zippora Lupowitz
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 68(1-2)
Melatonin, the hormone secreted by the pineal gland at night, has recently been found to attenuate growth and viability of benign human prostate epithelial cells. Estradiol suppressed these responses by effecting a protein kinase C mediated inactivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5f942a1a02393a4ec4c18b8a5ce0a0
https://pubmed.ncbi.nlm.nih.gov/10215041
https://pubmed.ncbi.nlm.nih.gov/10215041
Publikováno v:
European Urology Supplements. 1:52
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a35749a750f9ec523dc6f2b65d10f6f
https://doi.org/10.1016/s1569-9056(02)80194-4
https://doi.org/10.1016/s1569-9056(02)80194-4