Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Zipora Etzion"'
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164743 (2016)
White Blood Cell (WBC) count, %HbF, and serum creatinine (Cr), have been identified as markers for increased mortality in sickle cell anemia (SCA) but no studies have examined the significance of longitudinal rate of change in these or other biomarke
Externí odkaz:
https://doaj.org/article/d4eff363319443f89d048a08d072a7f4
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133116 (2015)
Sickle cell anemia has many sequelae that result in emergency department (ED) use, but a minority of patients with sickle cell disease are frequent utilizers and make up the majority of ED visits. If patients who are likely to be frequent ED can be i
Externí odkaz:
https://doaj.org/article/a358803623d74c03891c8f29cfad6919
Publikováno v:
The Journal of General Physiology
The Ca(2+)-sensitive K(+) channel of human red blood cells (RBCs) (Gardos channel, hIK1, hSK4) was implicated in the progressive densification of RBCs during normal senescence and in the mechanism of sickle cell dehydration. Saturating RBC Ca(2+) loa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0133116 (2015)
PLoS ONE, Vol 10, Iss 8, p e0133116 (2015)
Introduction Sickle cell anemia has many sequelae that result in emergency department (ED) use, but a minority of patients with sickle cell disease are frequent utilizers and make up the majority of ED visits. If patients who are likely to be frequen
Autor:
Robin W. Briehl, Maria Rotter, Frank A. Ferrone, Robert M. Bookchin, Alexey Aprelev, Zipora Etzion
Publikováno v:
Biophysical Journal. 88(4):2815-2822
Pathology in sickle cell disease begins with nucleation-dependent polymerization of deoxyhemoglobin S into stiff, rodlike fibers that deform and rigidify red cells. We have measured the effect of erythrocyte membranes on the rate of homogeneous nucle
Autor:
Zipora Etzion, Teresa Tiffert, Robert M. Bookchin, Virgilio L. Lew, Amanda J. Edgley, Julia E. Raftos
Publikováno v:
American Journal of Physiology-Cell Physiology. 280:C1449-C1454
The ATPase activity of the plasma membrane Ca2+pump (PMCA) has been reported to be inhibited by exposure of red blood cell (RBC) PMCA preparations to high glucose concentrations. It has been claimed that this effect could have potential pathophysiolo
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164743 (2016)
PLoS ONE
PLoS ONE
Introduction White Blood Cell (WBC) count, %HbF, and serum creatinine (Cr), have been identified as markers for increased mortality in sickle cell anemia (SCA) but no studies have examined the significance of longitudinal rate of change in these or o
Autor:
Robert M. Bookchin, Virgilio L. Lew, Jeremy N. Skepper, Narla Mohandas, Martin Sorette, Zipora Etzion
Publikováno v:
Proceedings of the National Academy of Sciences. 97:8045-8050
We describe a population of sickle cell anemia red cells (SS RBCs) (≈4%) and a smaller fraction of normal RBCs (+ with either valinomycin or elevated internal Ca 2+ . The nonshrinking, valinomycin-resistant ( val-res ) fractions, first detected by
Autor:
Mary E. Fabry, Dhananjay K. Kaul, Anne C. Rybicki, Eric E. Bouhassira, Kitty de Jong, Qiuying Chen, Joseph E. Canterino, Edna K. Akoto, Sandra M. Suzuka, Frans A. Kuypers, David J. Lefer, Tatiana C. Balazs, Rhoda Elison Hirsch, Zipora Etzion
Hemoglobin (Hb) E (β26 Glu→Lys) is the most common abnormal hemoglobin (Hb) variant in the world. Homozygotes for HbE are mildly thalassemic as a result of the alternate splice mutation and present with a benign clinical picture (microcytic and mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b3867a4cb77ec504aa671f0545ae19
https://europepmc.org/articles/PMC3310900/
https://europepmc.org/articles/PMC3310900/
Publikováno v:
Cell calcium. 45(3)
The activity of the plasma membrane Ca 2+ -pump decreases steeply throughout the 120 days lifespan of normal human red blood cells. Experiments with isolated membrane preparations showed that glycation of a lysine residue near the catalytic site of t