Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Zining Wu"'
Autor:
Colin H. Macphee, Xinzhong Dong, Qi Peng, Daniel V. Paone, Per Stahl Skov, Katrine Baumann, Theresa Roethke, Deborah A. Goldspink, Samuel K. Pearson, Zining Wu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionBecause MRGPRX2 is now recognized as the mast cell receptor for basic secretagogues, there is currently a tremendous interest in whether MRGRPX2 could play an important role in various pruritic dermatoses such as chronic spontaneous urtic
Externí odkaz:
https://doaj.org/article/7ca26fa053aa43d89ee499f20b3dde40
Autor:
Tao Lu, Changsheng Zhu, Hao Cui, Zining Wu, Zhengyang Lu, Yanhai Meng, Qiulan Yang, Liukun Meng, Yunhu Song, Shuiyun Wang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 20 (2024)
Background The clinical characteristics and survival outcomes of patients who underwent concomitant coronary artery bypass grafting during septal myectomy have not been well studied. Methods and Results We reviewed patients who underwent both septal
Externí odkaz:
https://doaj.org/article/a65535ce0d304639b202e66951c175a3
Autor:
Peter W. West, Jérémy Chéret, Rajia Bahri, Orsolya Kiss, Zining Wu, Colin H. Macphee, Silvia Bulfone-Paus
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110984- (2024)
Summary: Mast cells (MCs) are tissue-resident immune cells known to degranulate in response to FcεRI crosslinking or MRGPRX2 engagement. MCs are found close to nerves, but the mechanisms that regulate this privileged localization remain unclear. Her
Externí odkaz:
https://doaj.org/article/0ebe03746b034342af49104ab4d42dd5
Autor:
Shijun Xu, Jie Liu, Lei Li, Zining Wu, Jiachen Li, Yongmin Liu, Junming Zhu, Lizhong Sun, Xinliang Guan, Ming Gong, Hongjia Zhang
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 14, Iss 1, Pp 1-11 (2019)
Abstract Background Thoracic aortic surgery and cardiopulmonary bypass are both associated with development of postoperative acute kidney injury. In this study, we undertook to investigate the relationship between cardiopulmonary bypass time and post
Externí odkaz:
https://doaj.org/article/2924ecaeed0e4a02b20381d32ba6baa6
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 14, Iss 1, Pp 1-9 (2019)
Abstract Background The purpose of this study is to identify the risk factors for postoperative severe hypoxemia after surgery for acute type A aortic dissection. Methods This was a single-center retrospective study including 112 consecutive patients
Externí odkaz:
https://doaj.org/article/35629109368d43f8bf5eef8071704cb1
Autor:
Aidan G. Gilmartin, Arthur Groy, Elizabeth R. Gore, Charity Atkins, Edward R. Long, Monica N. Montoute, Zining Wu, Wendy Halsey, Dean E. McNulty, Daniela Ennulat, Lourdes Rueda, Melissa Pappalardi, Ryan G. Kruger, Michael T. McCabe, Ali Raoof, Roger Butlin, Alexandra Stowell, Mark Cockerill, Ian Waddell, Donald Ogilvie, Juan Luengo, Allan Jordan, Andrew B. Benowitz
Publikováno v:
Haematologica, Vol 106, Iss 7 (2020)
Pharmacological induction of fetal hemoglobin (HbF) expression is an effective therapeutic strategy for the management of beta-hemoglobinopathies such as sickle cell disease. DNA methyltransferase (DNMT) inhibitors 5-azacytidine (5-aza) and 5-aza-2
Externí odkaz:
https://doaj.org/article/375cf7300ce44f4d81582faca63eef19
Autor:
Shijun Xu, Lei Li, Yuwei Fu, Xin Wang, Hairui Sun, Jianbin Wang, Lu Han, Zining Wu, Yongmin Liu, Junming Zhu, Lizhong Sun, Feng Lan, Yihua He, Hongjia Zhang
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 1, Pp n/a-n/a (2020)
Abstract Background Marfan syndrome (MFS) is an inherited connective tissue disease that mainly involves Fibrillin‐1 (FBN1) mutations and aortic manifestations. In this study, we investigated the correlations between the FBN1 genotype–phenotype a
Externí odkaz:
https://doaj.org/article/13bcde1bf725409399411f4bb2c104ce
Autor:
Jak Grimes, Sapna Desai, Neil W. Charter, James Lodge, Rita Moita Santos, Albert Isidro‐Llobet, Andrew M. Mason, Zining Wu, Lawrence A. Wolfe III, Lakshmi Anantharaman, Andrew Green, Angela M. Bridges, Deidre A. Dalmas Wilk, Andrew J. Brown
Publikováno v:
Pharmacology Research & Perspectives, Vol 7, Iss 6, Pp n/a-n/a (2019)
Abstract Activation of MrgX2, an orphan G protein‐coupled receptor expressed on mast cells, leads to degranulation and histamine release. Human MrgX2 binds promiscuously to structurally diverse peptides and small molecules that tend to have basic p
Externí odkaz:
https://doaj.org/article/d52477c4710a45b380964101c0429cd7
Autor:
Xin Zeng, Robert Kirkpatrick, Glenn Hofmann, Didier Grillot, Valerie Linhart, Fabrice Viviani, Joseph Marino, Joseph Boyer, Taylor L Graham, Quinn Lu, Zining Wu, Andrew Benowitz, Rick Cousins
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0207140 (2018)
Atonal homolog 1 (Atoh1) is a basic helix-loop-helix 9 (bHLH) transcription factor acting downstream of Notch and is required for the differentiation of sensory hair cells in the inner ear and the specification of secretory cells during the intestina
Externí odkaz:
https://doaj.org/article/656109b149fa41a9b622668bf276f068
Autor:
David J Rickard, Clark A Sehon, Viera Kasparcova, Lorena A Kallal, Pamela A Haile, Xin Zeng, Monica N Montoute, Derek D Poore, Hu Li, Zining Wu, Patrick M Eidam, John G Emery, Robert W Marquis, Peter J Gough, John Bertin
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96737 (2014)
NOD1 is an intracellular pattern recognition receptor that recognizes diaminopimelic acid (DAP), a peptidoglycan component in gram negative bacteria. Upon ligand binding, NOD1 assembles with receptor-interacting protein (RIP)-2 kinase and initiates a
Externí odkaz:
https://doaj.org/article/d8966b29a270430a972aa590bfa33f4f