Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Zining Hao"'
Autor:
Weidong Zhang, Liang Dai, Na Wang, Yunhe Liu, Zining Hao, Yaqian He, Song Ni, Yimin Wang, Dawei Gao
Publikováno v:
Cancer Nanotechnology, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Background The poor targeting delivery efficiency and limited efficacy of single therapeutic approach have consistently posed significant challenges in tumor management. Results In this research, we have conceived and synthesized a dual-targ
Externí odkaz:
https://doaj.org/article/999d3dc6f04147578951a26662e3a312
Publikováno v:
Science China Materials. 64:1021-1034
Hypoxia is a hallmark of solid tumors, and it significantly impairs the overall anticancer efficacy, particularly photodynamic therapy (PDT). Herein, a catalase-like nanovesicle with near-infrared light-responsiveness, that is, platinum/gold nanoshel
Autor:
Cheng Rao, Chunhui Li, Dawei Gao, Yuchu He, Zhenhe Ma, Yaqian He, Hongming Lou, Zining Hao, Menghan Yu, Cong Cong
Publikováno v:
Materials Horizons. 7:3266-3274
The advancement of anti-tumor nanomedicines is restricted by the delivery efficiency owing to a lack of insight into the intratumoral delivery mechanism, especially traversing the biological barriers. Herein, we explore a new strategy focusing on con
Autor:
Zining Hao, Yuchu He, Jing Wang, Xuwu Zhang, Fei Ye, Ze Guan, Xiaokang Liu, Zhenhe Ma, Yi Yuan, Hongming Lou, Dawei Gao
Publikováno v:
Chemical Engineering Journal. 446:137196
Autor:
Weidong Zhang, Shuzhen Chu, Desong Wang, L.H. Liu, Xin Cheng, Zining Hao, Jianmin Gu, Cong Cong, Dawei Gao, Tiantian Zhang, Song Ni
Publikováno v:
Biomaterials science. 9(18)
Single tumor starvation therapy can activate other signaling pathways in tumor cells and easily induce tumor cell metastasis. This research proposes an intelligent nanoparticle, which is effectively combined with plasmonic and immunotherapy to realiz
Autor:
Qianqian Zhao, Chunhui Li, Dawei Gao, Xuwu Zhang, Zining Hao, Hongyu He, Tian Yin, Yaqian He, Shuai Wang
Publikováno v:
ACS Biomaterials Science & Engineering. 5:4474-4484
The application of peptide-based biomaterials in nanocarriers can effectively reduce toxicity and improve the biocompatibility. In our study, a dual stimuli-responsive peptide-based drug delivery system was designed and synthesized, which was nontoxi
Autor:
Zining Hao, Hongyu He, Qianqian Zhao, Chunhui Li, Yaqian He, Dawei Gao, Shuai Wang, Zhiwei Liu, Liyao Luo
Publikováno v:
ACS Biomaterials Science & Engineering. 5:1321-1331
Limited therapeutic effects and obvious side effects are two critical problems affecting tumor therapy. Herein, we designed an ingenious nanocarrier, platinum/gold bimetallic-nanoshell-coated triptolide liposomes (Pt@Au-TP-Lips), to achieve enhanced
Autor:
Chunhui Li, Shanshan Xing, Shuxian Zhao, Qianqian Zhao, Yaqian He, Lei Li, Hongyu He, Weiwei Cao, Dawei Gao, Zining Hao, Shuai Wang
Publikováno v:
ACS biomaterials scienceengineering. 5(7)
Chemotherapy is one of the most effective methods of treating tumors in clinical study currently, but drug side effects usually are unbearable to the patient, which also makes it difficult to continue chemotherapy. Enhanced drug efficacy and reduced
Publikováno v:
Journal of materials chemistry. B. 8(23)
Gold nanomaterials (GNMs) are used in photothermal therapy due to their superior optical properties and excellent biocompatibility. However, the complex preparation process involving seed-mediated growth limits further clinical applications of GNMs.
Publikováno v:
ACS applied materialsinterfaces. 12(8)
Cells in the center of solid tumors have always been an abyss untouched by treatments because of their deep location and increased drug resistance. Herein, we designed a rational strategy for sequential intra-intercellular delivery of nanomedicine to