Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Zineb Belcaid"'
Autor:
Jiajia Zhang, Julie R Brahmer, Patrick M Forde, Tanguy Seiwert, Valsamo Anagnostou, Samuel Rosner, Victor E Velculescu, James R White, Joshua E Reuss, Gavin Pereira, Vincent Lam, Christine Hann, Michael Hwang, Kristen Marrone, Kellie N Smith, Joseph C Murray, Jamie E Chaft, Lavanya Sivapalan, Jenna Vanliere Canzoniero, Guangfan Zhang, Zineb Belcaid, Christopher Cherry, Archana Balan, Alexandria Curry, Noushin Niknafs, Qing Kay Li, Benjamin P Levy
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/da2666dd4bbf43a0ba1fac37b8c8e007
Autor:
Anne Kleijn, Wouter van den Bossche, Erik S. Haefner, Zineb Belcaid, Chantal Burghoorn-Maas, Jenneke J. Kloezeman, Suzan D. Pas, Sieger Leenstra, Reno Debets, Jeroen de Vrij, Clemens M.F. Dirven, Martine L.M. Lamfers
Publikováno v:
Molecular Therapy: Oncolytics, Vol 5, Iss C, Pp 11-19 (2017)
The conditionally replicating oncolytic adenovirus Delta24-RGD (Ad) is currently under investigation in clinical trials for glioblastoma, including in combination with temozolomide (TMZ), the standard chemotherapy for this tumor. Previously, we showe
Externí odkaz:
https://doaj.org/article/638eb206e27f41b2bcb5dca670a9a6cd
Autor:
Russell Maxwell, Andrew S. Luksik, Tomas Garzon-Muvdi, Alice L. Hung, Eileen S. Kim, Adela Wu, Yuanxuan Xia, Zineb Belcaid, Noah Gorelick, John Choi, Debebe Theodros, Christopher M. Jackson, Dimitrios Mathios, Xiaobu Ye, Phuoc T. Tran, Kristin J. Redmond, Henry Brem, Drew M. Pardoll, Lawrence R. Kleinberg, Michael Lim
Publikováno v:
OncoImmunology, Vol 7, Iss 12 (2018)
Immune checkpoint blockade targeting programmed cell death protein 1 (PD-1) is emerging as an important treatment strategy in a growing list of cancers, yet its clinical benefits are limited to a subset of patients. Further investigation of tumor-int
Externí odkaz:
https://doaj.org/article/6c9d1d466f094be8842a3615d27c9a5f
Autor:
Alice L. Hung, Russell Maxwell, Debebe Theodros, Zineb Belcaid, Dimitrios Mathios, Andrew S. Luksik, Eileen Kim, Adela Wu, Yuanxuan Xia, Tomas Garzon-Muvdi, Christopher Jackson, Xiaobu Ye, Betty Tyler, Mark Selby, Alan Korman, Bryan Barnhart, Su-Myeong Park, Je-In Youn, Tamrin Chowdhury, Chul-Kee Park, Henry Brem, Drew M. Pardoll, Michael Lim
Publikováno v:
OncoImmunology, Vol 7, Iss 8 (2018)
The use of inhibitory checkpoint blockade in the management of glioblastoma has been studied in both preclinical and clinical settings. TIGIT is a novel checkpoint inhibitor recently discovered to play a role in cancer immunity. In this study, we sou
Externí odkaz:
https://doaj.org/article/5c158c786ed24843bf3f702d74cfb42f
Autor:
Rutger K. Balvers, Zineb Belcaid, Sanne K. van den Hengel, Jenneke Kloezeman, Jeroen de Vrij, Hiroaki Wakimoto, Rob C. Hoeben, Reno Debets, Sieger Leenstra, Clemens Dirven, Martine L.M. Lamfers
Publikováno v:
Viruses, Vol 6, Iss 8, Pp 3080-3096 (2014)
Oncolytic adenoviral vectors are a promising alternative for the treatment of glioblastoma. Recent publications have demonstrated the advantages of shielding viral particles within cellular vehicles (CVs), which can be targeted towards the tumor micr
Externí odkaz:
https://doaj.org/article/2668f9a73c0b4395a972d8b6dbf912a9
Autor:
Zineb Belcaid, Jillian A Phallen, Jing Zeng, Alfred P See, Dimitrios Mathios, Chelsea Gottschalk, Sarah Nicholas, Meghan Kellett, Jacob Ruzevick, Christopher Jackson, Emilia Albesiano, Nicholas M Durham, Xiaobu Ye, Phuoc T Tran, Betty Tyler, John W Wong, Henry Brem, Drew M Pardoll, Charles G Drake, Michael Lim
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101764 (2014)
Glioblastoma (GBM) is the most common malignant brain tumor in adults and is associated with a poor prognosis. Cytotoxic T lymphocyte antigen -4 (CTLA-4) blocking antibodies have demonstrated an ability to generate robust antitumor immune responses a
Externí odkaz:
https://doaj.org/article/3ae3cc2ee25d42759d46a7e49146e898
Publikováno v:
Clinical and Developmental Immunology, Vol 2011 (2011)
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults. Despite intensive treatment, the prognosis for patients with GBM remains grim with a median survival of only 14.6 months. Immunotherapy has emerged as a pr
Externí odkaz:
https://doaj.org/article/56ca2275fded47b9b913847468cf5651
Autor:
Lavanya Sivapalan, Wade T. Iams, Zineb Belcaid, Susan C. Scott, Noushin Niknafs, Archana Balan, James R. White, Prasad Kopparapu, Christopher Cann, Blair V. Landon, Gavin Pereira, Victor E. Velculescu, Christine L. Hann, Christine M. Lovly, Valsamo Anagnostou
Publikováno v:
Clinical Cancer Research. :OF1-OF14
Purpose: Patients with small-cell lung cancer (SCLC) have an exceptionally poor prognosis, calling for improved real-time noninvasive biomarkers of therapeutic response. Experimental Design: We performed targeted error-correction sequencing on 171 se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::513e58885b12014079a0fd6aed4019ec
https://doi.org/10.1158/1078-0432.ccr-22-2242
https://doi.org/10.1158/1078-0432.ccr-22-2242
Autor:
Noushin Niknafs, Archana Balan, Christopher Cherry, Karlijn Hummelink, Kim Monkhorst, Xiaoshan M. Shao, Zineb Belcaid, Kristen A. Marrone, Joseph Murray, Kellie N. Smith, Benjamin Levy, Josephine Feliciano, Christine L. Hann, Vincent Lam, Drew M. Pardoll, Rachel Karchin, Tanguy Y. Seiwert, Julie R. Brahmer, Patrick M. Forde, Victor E. Velculescu, Valsamo Anagnostou
Publikováno v:
Nature Medicine. 29:440-449
Tumor mutation burden is an imperfect proxy of tumor foreignness and has therefore failed to consistently demonstrate clinical utility in predicting responses in the context of immunotherapy. We evaluated mutations in regions of the genome that are u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c09aa02ded7b6871f42cf4e48e9f1c
https://doi.org/10.1038/s41591-022-02163-w
https://doi.org/10.1038/s41591-022-02163-w
Autor:
Valsamo Anagnostou, Christine M. Lovly, Christine L. Hann, Victor E. Velculescu, Gavin Pereira, Blair V. Landon, Christopher Cann, Prasad Kopparapu, James R. White, Archana Balan, Noushin Niknafs, Susan C. Scott, Zineb Belcaid, Wade T. Iams, Lavanya Sivapalan
Supplementary Tables S1-S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e22eb5617148b7eacd06b8ece6e90fb4
https://doi.org/10.1158/1078-0432.22652476.v1
https://doi.org/10.1158/1078-0432.22652476.v1
