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Distal colonocytes targeted by C. rodentium recruit T-cell help for barrier defence.

Autor: Zindl CL; Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA. carlenezindl@uabmc.edu., Wilson CG; Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Chadha AS; Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Duck LW; Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Cai B; Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Harbour SN; Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Nagaoka-Kamata Y; Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Hatton RD; Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Gao M; Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Figge DA; Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Weaver CT; Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA. cweaver@uabmc.edu.

Publikováno v: Nature [Nature] 2024 May; Vol. 629 (8012), pp. 669-678. Date of Electronic Publication: 2024 Apr 10.

A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts.

Autor: Zindl CL; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: carlenezindl@uabmc.edu., Witte SJ; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Laufer VA; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Gao M; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA; Informatics Institute, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Yue Z; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA; Informatics Institute, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Janowski KM; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Cai B; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Frey BF; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Silberger DJ; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Harbour SN; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Singer JR; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Turner H; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Lund FE; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Vallance BA; Department of Pediatrics, University of British Columbia, Vancouver, BC V6H 3V4, Canada., Rosenberg AF; Informatics Institute, University of Alabama at Birmingham, Birmingham, AL 35294, USA; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Schoeb TR; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Chen JY; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA; Informatics Institute, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Hatton RD; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Weaver CT; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: cweaver@uab.edu.

Publikováno v: Immunity [Immunity] 2022 Mar 08; Vol. 55 (3), pp. 494-511.e11.

Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis.

Autor: Singer JR; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA. jrsinger@uab.edu., Blosser EG; Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Obstetrics and Gynecology, Ochsner Health System, New Orleans, LA, USA., Zindl CL; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Silberger DJ; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Conlan S; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Laufer VA; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., DiToro D; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Deming C; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Kumar R; Center for Clinical and Translational Science Informatics Institute, University of Alabama at Birmingham, Birmingham, AL, USA., Morrow CD; Department of Cell Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA., Segre JA; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Gray MJ; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA., Randolph DA; Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA.; Division of Neonatal-Perinatal Medicine, Rocky Mountain Hospital for Children, Denver, CO, USA., Weaver CT; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA. cweaver@uab.edu.

Publikováno v: Nature medicine [Nat Med] 2019 Nov; Vol. 25 (11), pp. 1772-1782. Date of Electronic Publication: 2019 Nov 07.

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells.

Autor: DiToro D; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA., Winstead CJ; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA., Pham D; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA., Witte S; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA., Andargachew R; Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322, USA., Singer JR; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA., Wilson CG; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA., Zindl CL; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA., Luther RJ; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA., Silberger DJ; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA., Weaver BT; HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA., Kolawole EM; Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322, USA., Martinez RJ; Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322, USA., Turner H; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA., Hatton RD; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA., Moon JJ; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA., Way SS; Division of Infectious Diseases and Perinatal Institute, Cincinnati Children's Hospital, Cincinnati, OH 45229, USA., Evavold BD; Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322, USA., Weaver CT; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35203, USA. cweaver@uab.edu.

Publikováno v: Science (New York, N.Y.) [Science] 2018 Sep 14; Vol. 361 (6407).