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pro vyhledávání: '"Zinchenko A.A.I"'
Publikováno v:
Protein & Peptide Letters. 4:321-328
Abstract: An extensive net of hydrogen bonds including the active carboxyls and Tyr residue locating in the so-called 'flap' in pepsin-like enzymes was planned to be restored in molecule of HIV-1 protease. For this purpose, 5 mutations and 2 deletion