Zobrazeno 1 - 10
of 2 970
pro vyhledávání: '"Zinc binding"'
Publikováno v:
Journal of Taibah University for Science, Vol 18, Iss 1 (2024)
Zinc fingers represent a highly diverse structural domain, with P53 being a notable example among zinc-dependent transcription factors. The folding patterns of proteins in the cell are heavily influenced by the concentration of zinc. The potential fo
Externí odkaz:
https://doaj.org/article/cc34cc7f08a44a18a41dd2c24f7da223
Autor:
Fetian MH, Al-Balas QA
Publikováno v:
Advances and Applications in Bioinformatics and Chemistry, Vol Volume 17, Pp 21-32 (2024)
Mohammad H Fetian, Qosay A Al-Balas Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, JordanCorrespondence: Qosay A Al-Balas, Department of Medicinal Chemistry & Pharmacognos
Externí odkaz:
https://doaj.org/article/d35a2e39e2884ab68b5d62cba857f44c
Autor:
Khulood H. Oudah, Walaa R. Mahmoud, Fadi M. Awadallah, Azza T. Taher, Safinaz E.-S Abbas, Heba Abdelrasheed Allam, Daniela Vullo, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 12-23 (2023)
The present investigation reports the design and synthesis of three series of benzoylthioureido derivatives bearing either benzenesulfonamide 7a–f, benzoic acid 8a–f or ethylbenzoate 9a–f moieties. The synthesised compounds were screened for th
Externí odkaz:
https://doaj.org/article/9079e92375a74694abaf13dca32085d8
Autor:
Diaaeldin I. Abdallah, Elvin D. de Araujo, Naman H. Patel, Lina S. Hasan, Richard Moriggl, Oliver H. Krämer, Patrick T. Gunning
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 4, Pp 757-779 (2023)
Histone deacetylases (HDACs) are a class of zinc (Zn)-dependent metalloenzymes that are responsible for epigenetic modifications. HDACs are largely associated with histone proteins that regulate gene expression at the DNA level. This tight regulation
Externí odkaz:
https://doaj.org/article/34581887751b4ed39c2cde49dcc5b039
Autor:
Tatiana Sharonova, Petr Zhmurov, Stanislav Kalinin, Alessio Nocentini, Andrea Angeli, Marta Ferraroni, Mikhail Korsakov, Claudiu T. Supuran, Mikhail Krasavin
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 857-865 (2022)
A series of sulfamide fragments has been synthesised and investigated for human carbonic anhydrase inhibition. One of the fragments showing greater selectivity for cancer-related isoforms hCA IX and XII was co-crystalized with hCA II showing signific
Externí odkaz:
https://doaj.org/article/2a3dc5eb7f254984b17701835310cb94
Autor:
Citing Chen, Wan Li, Jialong Gao, Wenhong Cao, Xiaoming Qin, Huina Zheng, Haisheng Lin, Zhongqin Chen
Publikováno v:
Molecules, Vol 29, Iss 4, p 900 (2024)
Oysters contain significant amounts of the zinc element, which may also be found in their proteins. In this study, a novel zinc-binding protein was purified from the mantle of the oyster Magallana hongkongensis using two kinds of gel filtration chrom
Externí odkaz:
https://doaj.org/article/0bcea077420049a4b6415e2dd3dc464b
Autor:
Ana Iochabel Soares Moretti, Viktoria E. Baksheeva, Andrei Yu. Roman, Tiphany Coralie De Bessa, François Devred, Hervé Kovacic, Philipp O. Tsvetkov
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2095 (2024)
The interplay between metal ion binding and the activity of thiol proteins, particularly within the protein disulfide isomerase family, remains an area of active investigation due to the critical role that these proteins play in many vital processes.
Externí odkaz:
https://doaj.org/article/60674322f25d441790c3e03e0cc407a6
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