Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Zinayida Fandalyuk"'
Autor:
Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/0c0c030dc1c54c61a794787a99cca008
Autor:
May Eriksen‐Gjerstad, Ida Tveit Karlsen, Zinayida Fandalyuk, Susanne Benjaminsen, Fanny Baran‐Marszak, Bela Papp, Frederick Locke, Marcus Ladds, Andrés Pastor‐Fernández, Pascal Gelebart, Emmet Mc Cormack
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 913-918 (2022)
Abstract Mantle cell lymphoma (MCL) is a non‐Hodgkin lymphoma that remains incurable with the treatment options available today. In the present study, we have identified the dihydroorotate dehydrogenase (DHODH), an essential enzyme for the de novo
Externí odkaz:
https://doaj.org/article/89fe4f4068a64767b83320ef7c88e86c
Autor:
Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Abstract The development of non-genotoxic therapies that activate wild-type p53 in tumors is of great interest since the discovery of p53 as a tumor suppressor. Here we report the identification of over 100 small-molecules activating p53 in cells. We
Externí odkaz:
https://doaj.org/article/c70bab1df6ec4076bb2c93aa455abeeb
Autor:
Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)
The original PDF version of this Article listed the authors as “Marcus J.G.W. Ladds,” where it should have read “Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond et al.#”. Also in the PDF version, it was incorrectly st
Externí odkaz:
https://doaj.org/article/6b88c0d66cd64b709fb079a6627015c7
Autor:
Karin Larsson, Tanzina Mollick, Richard Svensson, Mireia Mayoral Safont, Emma M. Peat, Yan Zhao, Anna Lena Gustavsson, Chloe Tuck, David P. Lane, Gergana Popova, Anna R. McCarthy, Katarina Färnegårdh, Maureen Higgins, John Lunec, Ulrika Yngve, Marcus J.G.W. Ladds, Andrés Pastor Fernández, Nicholas J. Westwood, Emmet McCormack, Alan R. Healy, Ingeborg M.M. van Leeuwen, Suhas Darekar, Catherine J. Drummond, Martin Haraldsson, Pascal Gelebart, Mihaela Popa, Marijke C.C. Sachweh, Lars Johansson, Sonia Lain, Ravi Bhatia, Zinayida Fandalyuk, Vicent Pelechano, Agathe C.A. D'Hollander, Borivoj Vojtesek, Su Chu, Mar Carmena, William C. Earnshaw, Alastair M. Thompson, Saikiran K. Sedimbi, Marta Nekulova, Maria Håkansson, Aljona Saleh, Marie Arsenian-Henriksson, Johanna Campbell, Marcela Franco, Björn Walse
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Ladds, M J G W, van Leeuwen, I M M, Drummond, C J, Chu, S, Healy, A R, Popova, G, Pastor Fernández, A, Mollick, T, Darekar, S, Sedimbi, S K, Nekulova, M, Sachweh, M C C, Campbell, J, Higgins, M, Tuck, C, Popa, M, Safont, M M, Gelebart, P, Fandalyuk, Z, Thompson, A M, Svensson, R, Gustavsson, A-L, Johansson, L, Färnegårdh, K, Yngve, U, Saleh, A, Haraldsson, M, D'Hollander, A C A, Franco, M, Zhao, Y, Håkansson, M, Walse, B, Larsson, K, Peat, E M, Pelechano, V, Lunec, J, Vojtesek, B, Carmena, M, Earnshaw, W C, McCarthy, A R, Westwood, N J, Arsenian-Henriksson, M, Lane, D P, Bhatia, R, McCormack, E & Laín, S 2018, ' A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage ', Nature Communications, vol. 9, no. 1, 1107 (2018) . https://doi.org/10.1038/s41467-018-03441-3
Nature Communications
Ladds, M J G W, van Leeuwen, I M M, Drummond, C J, Chu, S, Healy, A R, Popova, G, Pastor Fernández, A, Mollick, T, Darekar, S, Sedimbi, S K, Nekulova, M, Sachweh, M C C, Campbell, J, Higgins, M, Tuck, C, Popa, M, Safont, M M, Gelebart, P, Fandalyuk, Z, Thompson, A M, Svensson, R, Gustavsson, A-L, Johansson, L, Färnegårdh, K, Yngve, U, Saleh, A, Haraldsson, M, D'Hollander, A C A, Franco, M, Zhao, Y, Håkansson, M, Walse, B, Larsson, K, Peat, E M, Pelechano, V, Lunec, J, Vojtesek, B, Carmena, M, Earnshaw, W C, McCarthy, A R, Westwood, N J, Arsenian-Henriksson, M, Lane, D P, Bhatia, R, McCormack, E & Laín, S 2018, ' A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage ', Nature Communications, vol. 9, no. 1, 1107 (2018) . https://doi.org/10.1038/s41467-018-03441-3
ML, CD, IvL, GP, TM, SD, MS, APF, CT, DL, MAH, KL and SL: project grants from the Swedish Research Council, the Swedish Cancer Society and the Swedish Childhood Cancer Foundation. MHi and JC: Cancer Research UK (C8/A6613). MC, EP and WE: Wellcome Tru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd2c01d2aabbdecaf13d8d9d9ac446c
http://link.springer.com/article/10.1038/s41467-018-03441-3
http://link.springer.com/article/10.1038/s41467-018-03441-3
Autor:
Simon N. Dankel, Thomas Skurk, Gunnar Mellgren, Agné Kulyté, Zinayida Fandalyuk, Peter Arner, Jørn V. Sagen, Hans Hauner, Therese H. Røst, Mikael Rydén
Publikováno v:
Metabolism: Clinical and Experimental
Background: Adipose tissue plays a crucial role in diet- and obesity-related insulin resistance, with implications for several metabolic diseases. Identification of novel target genes and mechanisms that regulate adipocyte function could lead to impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e3d46441d87ea78758dee98d9df7dc
https://doi.org/10.1016/j.metabol.2019.153999
https://doi.org/10.1016/j.metabol.2019.153999
Autor:
Mireia Mayoral Safont, Björn Walse, Katarina Färnegårdh, Lars Johansson, Marie Arsenian-Henriksson, Pascal Gelebart, Alan R. Healy, Marijke C.C. Sachweh, Johanna Campbell, Marcela Franco, Marta Nekulova, Richard Svensson, Maria Håkansson, Tanzina Mollick, Borivoj Vojtesek, Emmet McCormack, Anna Lena Gustavsson, Yan Zhao, Mar Carmena, John Lunec, Aljona Saleh, Sonia Lain, Ravi Bhatia, Anna R. McCarthy, Marcus J.G.W. Ladds, Saikiran K. Sedimbi, Suhas Darekar, Catherine J. Drummond, Zinayida Fandalyuk, Agathe C.A. D'Hollander, Vicent Pelechano, Ulrika Yngve, Su Chu, Karin Larsson, Alastair M. Thompson, Ingeborg M.M. van Leeuwen, Chloe Tuck, Martin Haraldsson, Mihaela Popa, Emma M. Peat, Gergana Popova, Maureen Higgins, Andrés Pastor Fernández, Nicholas J. Westwood, William C. Earnshaw, David P. Lane
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)
The development of non-genotoxic therapies that activate wild-type p53 in tumors is of great interest since the discovery of p53 as a tumor suppressor. Here we report the identification of over 100 small-molecules activating p53 in cells. We elucidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d805f7ca635514dcfc03b4f3e80cf7d7
https://doi.org/10.1038/s41467-018-04198-5
https://doi.org/10.1038/s41467-018-04198-5
Autor:
Simon N. Dankel, Matthias Blüher, Hans-Jørgen Nielsen, Zinayida Fandalyuk, Thomas Skurk, Melina Claussnitzer, Gunnar Mellgren, Jessica Svärd, Hans Hauner, Jørn V. Sagen, Viktoria Glunk, Margit H. Solsvik, Elise Grytten, Nora Klöting, Christian Busch, Simone Matthä
Publikováno v:
Obesity. 22:1807-1813
COL6A3 may modulate adipose tissue function in obesity and insulin resistance. A role for human adipocytes linking COL6A3 with insulin resistance warrants exploration.COL6A3 mRNA in abdominal subcutaneous adipose samples was compared between (1) BMI-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0929c7d95458fc39dd96f1408dd5da5f
https://doi.org/10.1002/oby.20758
https://doi.org/10.1002/oby.20758