Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zinah Wassouf"'
Autor:
Samantha L. Schaffner, Zinah Wassouf, Thomas Hentrich, Melanie Nuesch-Germano, Michael S. Kobor, Julia M. Schulze-Hentrich
Publikováno v:
Neurobiology of Disease, Vol 186, Iss , Pp 106274- (2023)
Elevated alpha-synuclein (SNCA) gene expression is associated with transcriptional deregulation and increased risk of Parkinson's disease, which may be partially ameliorated by environmental enrichment. At the molecular level, there is emerging evide
Externí odkaz:
https://doaj.org/article/4648fa4892ae4b0987d37c7733ea941c
Autor:
Libo Yu-Taeger, Thomas Ott, Paola Bonsi, Celina Tomczak, Zinah Wassouf, Giuseppina Martella, Giuseppe Sciamanna, Paola Imbriani, Giulia Ponterio, Annalisa Tassone, Julia M. Schulze-Hentrich, Rose Goodchild, Olaf Riess, Antonio Pisani, Kathrin Grundmann-Hauser, Huu Phuc Nguyen
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
Dystonia is a neurological movement disorder characterized by sustained or intermittent involuntary muscle contractions. Loss-of-function mutations in the GNAL gene have been identified to be the cause of “isolated” dystonia DYT25. The GNAL gene
Externí odkaz:
https://doaj.org/article/8a71ddea79364ff685249d5e5644b2ff
Autor:
Yogesh Singh, Mohamed El-Hadidi, Jakob Admard, Zinah Wassouf, Julia M. Schulze-Hentrich, Ursula Kohlhofer, Leticia Quintanilla-Martinez, Daniel Huson, Olaf Riess, Nicolas Casadei
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Recent findings suggest an implication of the gut microbiome in Parkinson’s disease (PD) patients. PD onset and progression has also been linked with various environmental factors such as physical activity, exposure to pesticides, head injury, nico
Externí odkaz:
https://doaj.org/article/50a718e324ff4673b165546b3984ab01
Autor:
Zinah Wassouf, Thomas Hentrich, Nicolas Casadei, Mirko Jaumann, Marlies Knipper, Olaf Riess, Julia M. Schulze-Hentrich
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2019)
Parkinson’s disease (PD) is a progressive neurodegenerative disorder with motor symptoms and a plethora of non-motor and neuropsychiatric features that accompany the disease from prodromal to advanced stages. While several genetic defects have been
Externí odkaz:
https://doaj.org/article/23308d8322834211af0762c65169f1c8
Autor:
C. Alejandra Morato Torres, Zinah Wassouf, Faria Zafar, Danuta Sastre, Tiago Fleming Outeiro, Birgitt Schüle
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 16, p 5724 (2020)
Neurodevelopmental and late-onset neurodegenerative disorders present as separate entities that are clinically and neuropathologically quite distinct. However, recent evidence has highlighted surprising commonalities and converging features at the cl
Externí odkaz:
https://doaj.org/article/8d48638942c34d22a4b5e2dc1a3ee215
Autor:
Zinah Wassouf, Thomas Hentrich, Sebastian Samer, Carola Rotermund, Philipp J. Kahle, Ingrid Ehrlich, Olaf Riess, Nicolas Casadei, Julia M. Schulze-Hentrich
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Onset and progression of neurodegenerative disorders, including synucleinopathies such as Parkinson's disease, have been associated with various environmental factors. A highly compelling association from a therapeutic point of view has been found be
Externí odkaz:
https://doaj.org/article/90ceed3b20be48ecac836caa5beb3cd3
Autor:
Mary Xylaki, Isabel Paiva, Mohammed Al-Azzani, Ellen Gerhardt, Gaurav Jain, Md Rezaul Islam, Eftychia Vasili, Zinah Wassouf, Julia M. Schulze-Hentrich, André Fischer, Tiago Fleming Outeiro
Publikováno v:
Journal of Parkinson's Disease : JPD
Journal of Parkinson's Disease 13(2), 179-196 (2023). doi:10.3233/JPD-225055
Journal of Parkinson's Disease 13(2), 179-196 (2023). doi:10.3233/JPD-225055
Background:Synucleinopathies are disorders characterized by the abnormal accumulation of α-synuclein (aSyn). Synaptic compromise is observed in synucleinopathies parallel to aSyn aggregation and is accompanied by transcript deregulation.Objective:We
Autor:
Nicolas Casadei, Jeannette Hübener-Schmid, James D. Mills, Olaf Riess, Eva Haas, Julia M. Schulze-Hentrich, Tiago F. Outeiro, Christine Ehrhardt, Zinah Wassouf, Thomas Hentrich, Eleonora Aronica
Publikováno v:
Aging. 12:18889-18906
Parkinson's disease (PD) is an age-dependent neurodegenerative disorder. Besides characteristic motor symptoms, patients suffer from cognitive impairments linked to pathology in cortical areas. Due to obvious challenges in tracing the underlying mole
Autor:
Michael Walter, Nicolas Casadei, Rejko Krueger, Peter A. Barbuti, Olaf Riess, Thomas Hentrich, Fubo Cheng, Kathrin Grundmann-Hauser, Zinah Wassouf, Thomas Ott, Julia M. Schulze-Hentrich
Publikováno v:
Journal of Molecular Neuroscience
Mutations in THAP1 (THAP domain-containing apoptosis-associated protein 1) are responsible for DYT6 dystonia. Until now, more than eighty different mutations in THAP1 gene have been found in patients with primary dystonia, and two third of them are m
Autor:
Samantha L Schaffner, Zinah Wassouf, Diana F Lazaro, Mary Xylaki, Nicole Gladish, David T S Lin, Julia MacIsaac, Katia Ramadori, Thomas Hentrich, Julia M Schulze-Hentrich, Tiago F Outeiro, Michael S Kobor
Publikováno v:
Human molecular genetics 31(21), 3694-3714 (2022). doi:10.1093/hmg/ddac104
Parkinson’s disease (PD) is a neurological disorder with complex interindividual etiology that is becoming increasingly prevalent worldwide. Elevated alpha-synuclein levels can increase risk of PD and may influence epigenetic regulation of PD pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9453219e199f5dd697dd1004d265b214