Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Zimra R. Israel"'
Autor:
Vidia Roopchard, Amjed Masood, Zimra R. Israel, Michele A. Kutzler, Shakuntala Megati, Maninder K. Sidhu, Dorys Garcia-Hand, Margherita Rosati, John H. Eldridge, Siew-Yen Chong, George N. Pavlakis, Michael A. Egan, David B. Weiner, Eva B. Schadeck, Jean D. Boyer, David C. Montefiori, Jorge Quiroz
Publikováno v:
Vaccine. 25:4967-4982
Plasmid-based IL-12 has been demonstrated to successfully enhance the immunogenicity of DNA vaccines, thus enabling a reduction of the amount of DNA required for immunization. IL-15 is thought to affect the maintenance and enhance effector function o
Autor:
Jean D. Boyer, Genoveffa Franchini, Norbert Bischofberger, George N. Pavlakis, Paul S. Albert, John H. Eldridge, Zimra R. Israel, Agneta von Gegerfelt, David B. Weiner, Candido Alicea, Jenifer Bear, Margherita Rosati, Barbara K. Felber, Patricia Roth, Antonio Valentin, Phillip D. Markham
Publikováno v:
Journal of Virology. 81:1972-1979
Rhesus macaques chronically infected with highly pathogenic simian immunodeficiency virus (SIV) SIVmac251 were treated with antiretroviral drugs and vaccinated with combinations of DNA vectors expressing SIV antigens. Vaccination during therapy incre
Autor:
Priscilla Piacente, Shakuntala Megati, Amjed Masood, Zimra R. Israel, John H. Eldridge, J. Erik Johnson, Dana L. Hasselschwert, Patricia A Reilly, John K. Rose, Kevin J Lopez, Preston A. Marx, David K. Clarke, David C. Montefiori, R. Michael Hendry, Stephen A. Udem, Mark G. Lewis, Eric M. Mishkin, Robert E Druilhet, Siew Yen Chong, Eva B. Schadeck, Paul W Barras, Nina F. Rose, Michael A. Egan
Publikováno v:
AIDS Research and Human Retroviruses. 20:989-1004
An experimental AIDS vaccine based on attenuated, recombinant vesicular stomatitis virus (rVSV), when administered by a combination of parenteral and mucosal routes, has proven effective at preventing AIDS in a rhesus macaque model (Rose NF, et al.:
Autor:
John H. Eldridge, Herman F. Staats, Priscilla Piacente, Ben-Jiang Ma, Zimra R. Israel, Barton F. Haynes, Siew Yen Chong, David C. Montefiori, Shakuntala Megati, Eva B. Schadeck, Michael Hagen, Michael A. Egan
Publikováno v:
Vaccine. 22:3774-3788
Cynomolgus macaques were immunized by either the intramuscular (i.m.) or intranasal (i.n.) route with a HIV-1 peptide-based immunogen (C4-V3 89.6P) alone, or formulated with novel adjuvants to evaluate the ability of the adjuvants to augment peptide-
Autor:
Jennifer Hu, Preston A. Marx, David T. Wilkens, Douglas F. Nixon, Zimra R. Israel, Walter J. Moretto, Binhua Ling, Amara Luckay, Barbara L. Shacklett, Ronald S. Veazey
Publikováno v:
AIDS Research and Human Retroviruses. 18:1081-1088
Despite repeated high-risk exposure to infectious HIV-1, some individuals remain HIV-1 seronegative and apparently uninfected. The use of nonhuman primate model systems to study SIVmac transmission may help to elucidate the factors responsible for pr
Autor:
Maninder K. Sidhu, S. Gascot, Melween I. Martínez, Zimra R. Israel, Idalí Martínez, Aftab A. Ansari, David C. Montefiori, M. Rivera, C. Colon, R. Stout, E. O'Neill, Francois Villinger, Teresa Arana, Edmundo Kraiselburd
Publikováno v:
Journal of Medical Primatology. 31:217-227
The ever increasing number of people infected by human immunodeficiency virus (HIV) throughout the world renders the development of effective vaccines an urgent priority. Herein, we report on an attempt to induce and enhance antiviral responses using
Autor:
Zimra R. Israel, Michael A. Egan
Publikováno v:
Clinical and Applied Immunology Reviews. 2:255-287
The direct injection of a naked plasmid DNA vaccine encoding a foreign antigen results in plasmid uptake and protein expression leading to the induction of antigen-specific cellular and humoral immune responses. The ability of DNA vaccine-elicited im
Autor:
Zimra R. Israel, Preston A. Marx
Publikováno v:
Journal of Medical Primatology. 24:53-60
To identify mucosal immunity in HIV-infected chimpanzees, IgG, IgA, and IgM from plasma, saliva, rectal swabs, vaginal washes, semen, and urethral washes were tested from four male and three female HIV-1IIIB infected chimpanzees. The level of HIV inf
Autor:
Zimra R. Israel, Donald H. Maul, Shawn P. O'Neil, Gregg A. Dean, Matthew J. Dreitz, James I. Mullins, Edward A. Hoover, Patricia N. Fultz
Publikováno v:
AIDS Research and Human Retroviruses. 9:277-286
We have studied the early pathogenesis of infection by molecular clone 1.9 of SIVsmmPBj14 in pig-tailed and cynomolgus macaques. Like the uncloned PBj14 parent, SIVsmmPBj14-1.9 consistently induced an acute clinical syndrome characterized by behavior
Autor:
Dorys Garcia-Hand, David B. Weiner, Shakuntala Megati, Maninder K. Sidhu, Amjed Masood, Margherita Rosati, Larry R. Smith, Siew-Yen Chong, Rong Xu, Sarah Cappello, Amara Luckay, Zimra R. Israel, Michael A. Egan, Solomon Sackitey, George N. Pavlakis, Barbara K. Felber, John H. Eldridge, Vidia Roopchand
Publikováno v:
Vaccine
Plasmid DNA (pDNA) vaccines are effective at eliciting immune responses in a wide variety of animal model systems, however, pDNA vaccines have generally been incapable of inducing robust immune responses in clinical trials. Therefore, to identify mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703aaa15fe077667bce3fcb2ec1c6077
https://europepmc.org/articles/PMC7294827/
https://europepmc.org/articles/PMC7294827/