New salicylamide and sulfonamide derivatives of quinoxaline 1,4-di-N-oxide with antileishmanial and antimalarial activities

Autor: Barea, C. (Carlos), Pabon, A. (Adriana), Castillo, D. (Denis), Zimic, M. (Mirko), Galiano, S. (Silvia), Pérez-Silanes, S. (Silvia), Monge, A. (Antonio), Deharo, E. (Eric), Aldana, I. (Ignacio)

Publikováno v: Dadun: Depósito Académico Digital de la Universidad de Navarra
Universidad de Navarra
Dadun. Depósito Académico Digital de la Universidad de Navarra
Consejo Superior de Investigaciones Científicas (CSIC)

Continuing with the efforts to identify new active compounds against malaria and leishmaniasis, fourteen new 3-amino-1,4-di-N-oxide quinoxaline-2-carbonitrile derivatives were synthesized and evaluated for their in vitro antimalarial and antileishman

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9b4493fec9ee87448e0d615cd6fd658b
https://hdl.handle.net/10171/61120

New quinoxaline 1,4-di-N-oxide derivatives: Trypanosomaticidal activities and enzyme docking simulation

Autor: Estevez, Y. (Yannick), Quiliano, M. (Miguel), Burguete, A. (Asunción), Cabanillas, B. (Billy), Zimic, M. (Mirko), Malaga, E. (Edith), Verastegui, M. (Manuela), Pérez-Silanes, S. (Silvia), Aldana, I. (Ignacio), Monge, A. (Antonio), Castillo, D. (Denis), Deharo, E. (Eric)

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
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Two series of pyrazol and propenone quinoxaline derivatives were tested for parasiticidal activity (against amastigotes of Leishmania peruviana and trypomastigotes of Trypanosoma cruzi) and for toxicity against proliferative and non-proliferative cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::177f68d9bb4e81cc109befefb7279238
https://hdl.handle.net/10171/35791