Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Zilong Bai"'
Autor:
Richard D. Bell, Matthew Brendel, Maxwell A. Konnaris, Justin Xiang, Miguel Otero, Mark A. Fontana, Zilong Bai, Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium, Daria M. Krenitsky, Nida Meednu, Javier Rangel-Moreno, Dagmar Scheel-Toellner, Hayley Carr, Saba Nayar, Jack McMurray, Edward DiCarlo, Jennifer H. Anolik, Laura T. Donlin, Dana E. Orange, H. Mark Kenney, Edward M. Schwarz, Andrew Filer, Lionel B. Ivashkiv, Fei Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Rheumatoid arthritis (RA) is a complex immune-mediated inflammatory disorder in which patients suffer from inflammatory-erosive arthritis. Recent advances on histopathology heterogeneity of RA synovial tissue revealed three distinct phenotyp
Externí odkaz:
https://doaj.org/article/b17d2655ca764faea6b9cae2cefd3a7a
Autor:
Chang Su, Yu Hou, Jielin Xu, Zhenxing Xu, Manqi Zhou, Alison Ke, Haoyang Li, Jie Xu, Matthew Brendel, Jacqueline R. M. A. Maasch, Zilong Bai, Haotan Zhang, Yingying Zhu, Molly C. Cincotta, Xinghua Shi, Claire Henchcliffe, James B. Leverenz, Jeffrey Cummings, Michael S. Okun, Jiang Bian, Feixiong Cheng, Fei Wang
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-22 (2024)
Abstract Parkinson’s disease (PD) is a serious neurodegenerative disorder marked by significant clinical and progression heterogeneity. This study aimed at addressing heterogeneity of PD through integrative analysis of various data modalities. We a
Externí odkaz:
https://doaj.org/article/c98b774780634551a2636756a95523ae
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103066- (2024)
Summary: The advent of single-cell multi-omics sequencing technology makes it possible for researchers to leverage multiple modalities for individual cells. Here, we present a protocol to perform integrative analysis of high-dimensional single-cell m
Externí odkaz:
https://doaj.org/article/b5eede18cadf4f34b66fe9783ce0a9f2
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundAmounting literatures have reported the significance of systemic inflammatory markers for evaluating tumor prognosis. But few studies have systematically compared their superiority and their impact on adjuvant chemotherapy.AimsWe aimed to i
Externí odkaz:
https://doaj.org/article/bafbaf0f16e74a33bd0ef435784f8b00
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background Cathepsin-K (CTSK) is overexpressed in Gastric cancer (GC) and the mechanism of its overexpression in GC is still unclear. The present work found CTSK as a potential predictive biomarker and immunotherapeutic target for GC based o
Externí odkaz:
https://doaj.org/article/bbc809e47c874b6893d43b6745a4ec35
Autor:
Yuanhua Nie, Longwen Xu, Zilong Bai, Yaoyao Liu, Shilong Wang, Qingnuo Zeng, Xuan Gao, Xuefeng Xia, Dongmin Chang
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Pancreatic cancer (PC) is a deadly disease. The tumor microenvironment (TME) participates in PC oncogenesis. This study focuses on the assessment of the prognostic and treatment utility of TME-associated genes in PC.Methods: After obtaini
Externí odkaz:
https://doaj.org/article/dc1088ce9b0b498c86ebcb3dc2bfd2a8
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 5, Pp 814-835 (2022)
Single-cell RNA sequencing (scRNA-seq) has become a routinely used technique to quantify the gene expression profile of thousands of single cells simultaneously. Analysis of scRNA-seq data plays an important role in the study of cell states and pheno
Externí odkaz:
https://doaj.org/article/f8ba1a122ec742f0a234618497b4a413
Autor:
Chang Su, Yu Hou, Manqi Zhou, Suraj Rajendran, Jacqueline R.M. A. Maasch, Zehra Abedi, Haotan Zhang, Zilong Bai, Anthony Cuturrufo, Winston Guo, Fayzan F. Chaudhry, Gregory Ghahramani, Jian Tang, Feixiong Cheng, Yue Li, Rui Zhang, Steven T. DeKosky, Jiang Bian, Fei Wang
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106460- (2023)
Summary: The abundance of biomedical knowledge gained from biological experiments and clinical practices is an invaluable resource for biomedicine. The emerging biomedical knowledge graphs (BKGs) provide an efficient and effective way to manage the a
Externí odkaz:
https://doaj.org/article/a540dcaf6ba642e2b4274b073c6cf5a8
Publikováno v:
ZooKeys, Vol 886, Iss , Pp 79-111 (2019)
Ten new species of the spider family Psilodercidae Machado, 1951 are described from tropical East Asia, including five species found in China: Sinoderces luohanensis Li & Li, sp. nov. (♂♀), S. xueae Li & Li, sp. nov. (♂♀), S. taichi Li & Li,
Externí odkaz:
https://doaj.org/article/6c7d440443004008abb7d1a93865b068
Publikováno v:
bioRxiv
The advent of single-cell multi-omics sequencing technology makes it possible for researchers to leverage multiple modalities for individual cells and explore cell heterogeneity. However, the high dimensional, discrete, and sparse nature of the data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf40d2ff1408f1d19c3a00e22c17050
https://europepmc.org/articles/PMC9915637/
https://europepmc.org/articles/PMC9915637/
