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Autor:
Feng Zhang, Jun Chen, Peter S. Vosler, Suping Wang, Armando P. Signore, R. Anne Stetler, Zili Xing, Hannah Yin, Wenjin Li, Yanqin Gao
Publikováno v:
Stroke. 39:2587-2595
Background and Purpose— NAD + is an essential cofactor for cellular energy production and participates in various signaling pathways that have an impact on cell survival. After cerebral ischemia, oxidative DNA lesions accumulate in neurons because