Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zikhona Njengele"'
Autor:
Njabulo Sondezi, Zikhona Njengele-Tetyana, Kgabo Phillemon Matabola, Thollwana Andretta Makhetha
Publikováno v:
ACS Omega, Vol 9, Iss 14, Pp 15959-15970 (2024)
Externí odkaz:
https://doaj.org/article/da67c85af0e44daf8be4e95adef15794
Autor:
Sinazo Z.Z. Cobongela, Maya M. Makatini, Zikhona Njengele-Tetyana, Lucky M. Sikhwivhilu, Nicole R.S. Sibuyi
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 8, Pp 105000- (2023)
Acyldepsipeptides (ADEPs) are receiving more attention as prospective antimicrobial agents due to their unique mode of action and chemical properties. However, their therapeutic potential is limited by their poor pharmacokinetic properties. Chemical
Externí odkaz:
https://doaj.org/article/1537182a5ba14c83a1de6a96a5718598
Autor:
Sinazo Z. Z. Cobongela, Maya M. Makatini, Bambesiwe May, Zikhona Njengele-Tetyana, Mokae F. Bambo, Nicole R. S. Sibuyi
Publikováno v:
Antibiotics, Vol 13, Iss 2, p 183 (2024)
The continuous rise in bacterial infections and antibiotic resistance is the driving force behind the search for new antibacterial agents with novel modes of action. Antimicrobial peptides (AMPs) have recently gained attention as promising antibiotic
Externí odkaz:
https://doaj.org/article/15d902c3f2144729bed7a632ed35497d
Autor:
Ndivhuwo P. Shumbula, Siyabonga S. Nkabinde, Zakhele B. Ndala, Siyasanga Mpelane, Morgan P. Shumbula, Phumlani S. Mdluli, Zikhona Njengele-Tetyana, Phumlani Tetyana, Thulani Hlatshwayo, Mbuso Mlambo, Nosipho Moloto
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 6, Pp 103798- (2022)
Fabrication of bioactive nanomaterials with improved stability and low toxicity towards healthy mammalian cells have recently been a topic of interest. Bioactive metal nanomaterials such as silver nanoparticles (AgNPs) tend to lose their stability wi
Externí odkaz:
https://doaj.org/article/4a4d61932a68447bab597d9015b806ef
Autor:
Ndivhuwo P. Shumbula, Zakhele B. Ndala, Siyabonga S. Nkabinde, Obakeng Nchoe, Khanani Macumele, Siyasanga Mpelane, Morgan P. Shumbula, Phumlane S. Mdluli, Nicole R.S. Sibuyi, Zikhona Njengele-Tetyana, Phumlani Tetyana, Mbuso Mlambo, Nosipho Moloto
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100635- (2022)
This work showcases the fabrication, characterization, antibacterial activity, and cytotoxicity of copper/polydopamine (Cu/PDA) nanocomposites. The nanocomposites were prepared by either embedding copper nanoparticles within the matrix (Cu-PDA) or in
Externí odkaz:
https://doaj.org/article/32a6e7089c68410dbfdf94af356c5abf
Autor:
Thulaganyo Domfe, Zikhona Njengele-Tetyana, Nikiwe Mhlanga, Phumlani Tetyana, Amanda Skepu, Jane Catherine Ngila, Lucky Mashudu Sikhwivhilu
Publikováno v:
Diagnostics, Vol 12, Iss 11, p 2664 (2022)
Rift Valley fever (RVF) is a mosquito-borne zoonotic disease that is caused by the Rift Valley fever virus (RVFV); Bunyaviridae: Phlebovirus. RVF disease can affect several different species, including ruminants, camels and humans and thus present a
Externí odkaz:
https://doaj.org/article/08b19ddef8ca4c4abbbf2bacef987966
The ability to detect even the slightest physiological change in the human body with high sensitivity and accurately monitor processes that impact human nature and their surroundings has led to an immense improvement in the quality of life. Biosensor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ceff99de3ae001819261806f07d03a
http://www.intechopen.com/articles/show/title/biosensors-design-development-and-applications
http://www.intechopen.com/articles/show/title/biosensors-design-development-and-applications
Publikováno v:
Protein Expression and Purification. 188:105969
HIV-1 virus release from infected cells is blocked by human BST-2, but HIV-1 Vpu efficiently antagonises BST-2 due to direct transmembrane domain interactions that occur between each protein. Targeting the interaction between these two proteins is se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca439908bff3a2bc5eb7324c23253d0
https://doi.org/10.1016/j.pep.2021.105969
https://doi.org/10.1016/j.pep.2021.105969
Publikováno v:
Protein Expression and Purification. 128:109-114
Vpu is one of four accessory proteins encoded by human immunodeficiency virus type I (HIV-1). Vpu modulates the expression of several cellular restriction factors within the HIV-1 infected cell including CD4, CD74, the bone marrow stromal antigen 2 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd713eac6f3630f6af7efb088b87c75
https://doi.org/10.1016/j.pep.2016.08.018
https://doi.org/10.1016/j.pep.2016.08.018
Autor:
E. Mabel Coyanis, Zikhona Njengele, Yasien Sayed, Thompho J. Rashamuse, Salerwe Mosebi, Moira L. Bode
Publikováno v:
European Journal of Medicinal Chemistry. 190:112111
Novel ethyl 2-(5-aryl-1H-imidazol-1-yl)-acetates 17 and propionates 18, together with their acetic acid 19 and acetohydrazide 20 derivatives, were designed and synthesized using TosMIC chemistry. Biological evaluation of these newly synthesized scaff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d25f11741c32d95324d2f14cf423576
https://doi.org/10.1016/j.ejmech.2020.112111
https://doi.org/10.1016/j.ejmech.2020.112111