Zika virus prM protein contains cholesterol binding motifs required for virus entry and assembly

Autor: Sarah Goellner, Giray Enkavi, Vibhu Prasad, Solène Denolly, Sungmin Eu, Giulia Mizzon, Leander Witte, Waldemar Kulig, Zina M. Uckeley, Teresa M. Lavacca, Uta Haselmann, Pierre-Yves Lozach, Britta Brügger, Ilpo Vattulainen, Ralf Bartenschlager

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)

Abstract For successful infection of host cells and virion production, enveloped viruses, including Zika virus (ZIKV), extensively rely on cellular lipids. However, how virus protein–lipid interactions contribute to the viral life cycle remains unc

Externí odkaz: https://doaj.org/article/c80f076b90924328a6a5af50c805c795

A bacterium‐like particle vaccine displaying Zika virus prM‐E induces systemic immune responses in mice.

Autor: Jin, Hongli^1,2 (AUTHOR), Bai, Yujie¹ (AUTHOR), Wang, Jianzhong³ (AUTHOR), Jiao, Cuicui¹ (AUTHOR), Liu, Di^1,3 (AUTHOR), Zhang, Mengyao¹ (AUTHOR), Li, Entao² (AUTHOR), Huang, Pei¹ (AUTHOR), Gong, Zhiyuan¹ (AUTHOR), Song, Yumeng¹ (AUTHOR), Xu, Shengnan² (AUTHOR), Feng, Na² (AUTHOR), Zhao, Yongkun² (AUTHOR), Wang, Tiecheng² (AUTHOR), Li, Nan² (AUTHOR), Gao, Yuwei² (AUTHOR), Yang, Songtao² (AUTHOR), Zhang, Haili¹ (AUTHOR), Li, Yuanyuan¹ (AUTHOR), Xia, Xianzhu^1,2 (AUTHOR)

Publikováno v: Transboundary & Emerging Diseases. Sep2022, Vol. 69 Issue 5, pe2516-e2529. 14p.

An inactivated recombinant rabies virus displaying the Zika virus prM-E induces protective immunity against both pathogens.

Autor: Hongli Jin, Cuicui Jiao, Zengguo Cao, Pei Huang, Hang Chi, Yujie Bai, Di Liu, Jianzhong Wang, Na Feng, Nan Li, Yongkun Zhao, Tiecheng Wang, Yuwei Gao, Songtao Yang, Xianzhu Xia, Hualei Wang

Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009484 (2021)

The global spread of Zika virus (ZIKV), which caused a pandemic associated with Congenital Zika Syndrome and neuropathology in newborns and adults, prompted the pursuit of a safe and effective vaccine. Here, three kinds of recombinant rabies virus (R

Externí odkaz: https://doaj.org/article/ba885491555e46738a09e5d5f956d0ae

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A bacterium-like particle vaccine displaying Zika virus prM-E induces systemic immune responses in mice

Autor: Gao Yuwei, Cuicui Jiao, Tiecheng Wang, Nan Li, Pei Huang, Yongkun Zhao, Yang Songtao, Yumeng Song, Entao Li, Jianzhong Wang, Zhiyuan Gong, Hongli Jin, Di Liu, Shengnan Xu, Hualei Wang, Feng Na, Mengyao Zhang, Yujie Bai, Xianzhu Xia

The emergence of Zika virus (ZIKV) infection, which is an unexpectedly associated with congenital defects, has prompted the development of safe and effective vaccines. The gram-positive enhancer matrix-protein anchor (GEM-PA) display system has emerg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db8c4ffa06bb809096b77e8c79fefd0f
https://doi.org/10.1101/2021.08.13.456215