Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zijun LAI"'
Publikováno v:
康复学报, Vol 26, Pp 34-39 (2016)
Objective:To explore the effect and underlying mechanism of Hedyotis diffusa Willd (HDW) on drug efflux and regulation of Hedgehog (HH) signaling pathway in human colorectal cancer HCT-8/5-FU cells.Methods:HCT-8/5-FU Cells were treated with different
Externí odkaz:
https://doaj.org/article/11dd4429f083449aa381c2a0864a1ad0
Autor:
ZIJUN LAI1,2, ZHAOKUN YAN1,2, JUN PENG1,2, JIANYU FENG1,2, QIONGYU LI1,2, YIYI JIN1,2, JIUMAO LIN1,2, WUJIN CHEN3
Publikováno v:
Molecular Medicine Reports. Nov2017, Vol. 16 Issue 5, p7752-7758. 7p. 6 Graphs.
Autor:
Qiongyu Li, Zhaokun Yan, Yiyi Jin, Zijun Lai, Lihui Wei, Jun Peng, Jiumao Lin, Jianyu Feng, Hong Yang
Publikováno v:
Oncology Reports. 38:2293-2300
5-Fluorouracil (5-FU) resistance or multidrug resistance (MDR) has become a major obstacle in clinical treatment of cancers including colorectal cancer (CRC). Aberrant activation of phosphatidylinositol 3 kinase (PI3K)/protein kinase B (AKT) pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c333ee350c8d46dc93e128419e34aeb
https://doi.org/10.3892/or.2017.5892
https://doi.org/10.3892/or.2017.5892
Publikováno v:
Oncology Reports.
Colorectal cancer (CRC) is one of the most commonly diagnosed malignancies worldwide. For patients diagnosed with the presence of metastatic disease, surgery is not suitable for the majority of them. Lymphangiogenesis is a key factor during cancer me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9354d69efb022becf0ad1a4211dac1b
https://doi.org/10.3892/or.2019.7223
https://doi.org/10.3892/or.2019.7223
Publikováno v:
Oncology Reports. 36:3568-3576
Colorectal cancer (CRC) is one of the most common malignancies worldwide. The majority of patients are not suitable for surgery due to the presence of metastatic disease at the time of diagnosis, which has led to a high mortality rate for patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a968f69ad042f458d8a0d3d851d8a3
https://doi.org/10.3892/or.2016.5186
https://doi.org/10.3892/or.2016.5186
Publikováno v:
Oncology Letters
Recent studies have indicated that the inflammatory microenvironment plays a significant role in colorectal cancer (CRC). The interleukin-6/signal transducer and activator of transcription 3 (IL-6/STAT3) signaling pathway mediates the proliferative a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf3d9ae0eac1e97df770c6b72bbe900
http://europepmc.org/articles/PMC4356405
http://europepmc.org/articles/PMC4356405
Publikováno v:
Molecular Medicine Reports.
Hedyotis diffusa Willd (HDW) is a major component frequently used in Traditional Chinese Medicine for the clinical treatment of colorectal cancer (CRC) and its associated drug resistance. However, the underlying mechanism of HDW circumventing drug re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634a493483852aeb28f4700c1aaac43c
https://doi.org/10.3892/mmr.2017.7903
https://doi.org/10.3892/mmr.2017.7903
Autor:
Wujin Chen, Jun Peng, Zijun Lai, Yiyi Jin, Jiumao Lin, Hong Yang, Zhaokun Yan, Ling Zhang, Jianyu Feng
Publikováno v:
Oncology Letters.
Hedyotis diffusa Willd (HDW) is a widely used traditional Chinese medicine in clinical therapy to treat various types of cancer, including colorectal cancer (CRC), but its effective polar fractions and functional mechanisms remain unclear. The aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c9537314c3c5d8d7930aaaf05b3702
https://doi.org/10.3892/ol.2017.7245
https://doi.org/10.3892/ol.2017.7245
Publikováno v:
Oncology Letters.
The development of colorectal cancer (CRC) is strongly associated with the imbalance of various intracellular signal transduction cascades, including protein kinase B (AKT), mitogen-activated protein kinase 1 (MAPK), signal transducer and activator o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855a6b04438b947b4a7c624f04c63c9b
https://doi.org/10.3892/ol.2017.7244
https://doi.org/10.3892/ol.2017.7244
Metastasis is one of the most aberrant behaviors of cancer cells. Patients with cancers, including colorectal cancer (CRC), have a higher risk of tumor recurrence and cancer-related mortality once metastasis is diagnosed. Existing treatment strategie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a512231a21eba6e774f015eaf613b9e6
https://europepmc.org/articles/PMC5740531/
https://europepmc.org/articles/PMC5740531/
