Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Zihua Zeng"'
Autor:
Ling Tao, Mahmoud A. Mohammad, Giorgio Milazzo, Myrthala Moreno-Smith, Tajhal D. Patel, Barry Zorman, Andrew Badachhape, Blanca E. Hernandez, Amber B. Wolf, Zihua Zeng, Jennifer H. Foster, Sara Aloisi, Pavel Sumazin, Youli Zu, John Hicks, Ketan B. Ghaghada, Nagireddy Putluri, Giovanni Perini, Cristian Coarfa, Eveline Barbieri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Half of high-risk neuroblastoma patients have MYCN amplification. Here, the authors show that MYCN induces fatty acid uptake and synthesis to support neuroblastoma and inhibition of a fatty acid transporter impairs tumor progression in preclinical mo
Externí odkaz:
https://doaj.org/article/f46634316a174b53a1daa084ab8c5d23
Publikováno v:
Nanomaterials, Vol 13, Iss 10, p 1666 (2023)
Titanium dioxide (TiO2) has garnered significant attention among various photocatalysts, whereas its photocatalytic activity is limited by its wide bandgap and inefficient charge separation, making the exploration of new strategies to improve its pho
Externí odkaz:
https://doaj.org/article/24e585a7befb48dbace5aee724d9acbf
Autor:
Jianjun Qi, Zihua Zeng, Zhenghu Chen, Cole Nipper, Xiaohui Liu, Quanyuan Wan, Jian Chen, Ching-Hsuan Tung, Youli Zu
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 558 (2022)
Gemcitabine is a chemotherapeutic used clinically to treat a variety of cancers. However, because it lacks tumor cell specificity, gemcitabine may cause off-target cytotoxicity and adversely impact patients. To impart cancer cell specificity to gemci
Externí odkaz:
https://doaj.org/article/1ba78e0a16fc440f9257bd2436ee8a53
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1221 (2021)
Doxorubicin (DOX) is a common anti-tumor drug that binds to DNA or RNA via non-covalent intercalation between G-C sequences. As a therapeutic agent, DOX has been used to form aptamer–drug conjugates for targeted cancer therapy in vitro and in vivo.
Externí odkaz:
https://doaj.org/article/7d93a86925ac4e0196ef030dad7c0e02
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 3, Iss C (2014)
The current antibody-mediated numeration assays of circulating tumor cells (CTCs) require multiple steps and are time-consuming. To overcome these technical limitations, a cancer cell-activatable aptamer-reporter was formulated by conjugating a bioma
Externí odkaz:
https://doaj.org/article/45b3b28415b94c2bbbe778884a597f94
Publikováno v:
Bioconjugate Chemistry. 32:1139-1145
Noninvasive in vivo imaging to measure the expression of EpCAM, a biomarker overexpressed in the majority of carcinoma tumors and metastatic lesions, is highly desirable for accurate tumor staging and therapy evaluation. Here, we report the use of an
Autor:
Jacky Wu, Jianjun Qi, Xiaohui Liu, Nina R. Boyle, Mehmet Sen, Quanyuan Wan, Michihisa Umetani, Xinping Fu, Vivek Kapur, Youli Zu, Zhenghu Chen, Pragya Manandhar, Victoria S. Cavener, Yi ling Wang, Xiaoliu Zhang, Zihua Zeng, Eric Salazar, Suresh V. Kuchipudi, Shu hsia Chen, Richard C. Willson
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (Weinheim an Der Bergstrasse, Germany)
Angewandte Chemie (Weinheim an Der Bergstrasse, Germany)
The receptor‐binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 spike (S) protein plays a central role in mediating the first step of virus infection to cause disease: virus binding to angiotensin‐converting enzyme 2 (ACE
Autor:
Ujwal Patil, Katerina Kourentzi, Youli Zu, Binh Vu, Dmitri Litvinov, Ana Prebisch, Mary Crum, Richard C. Willson, Zihua Zeng, Dimple Chavan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
Systemic anaplastic large cell lymphoma (ALCL) is an aggressive T-cell lymphoma most commonly seen in children and young adults. The majority of pediatric ALCLs are associated with the t(2;5)(p23;q35) translocation which fuses the Anaplastic Lymphoma
Publikováno v:
Mol Ther
Triple-negative breast cancer is an aggressive subtype of breast cancer that is primarily treated using systemic chemotherapy due to the lack of a specific cell surface marker for drug delivery. Cancer cell-specific aptamer-mediated drug delivery is
Autor:
Ling Tao, Mahmoud A. Mohammad, Giorgio Milazzo, Myrthala Moreno-Smith, Tajhal D. Patel, Barry Zorman, Andrew Badachhape, Blanca E. Hernandez, Amber B. Wolf, Zihua Zeng, Jennifer H. Foster, Sara Aloisi, Pavel Sumazin, Youli Zu, John Hicks, Ketan B. Ghaghada, Nagireddy Putluri, Giovanni Perini, Cristian Coarfa, Eveline Barbieri
Publikováno v:
Nature communications. 13(1)
Half of high-risk neuroblastoma patients have MYCN amplification. Here, the authors show that MYCN induces fatty acid uptake and synthesis to support neuroblastoma and inhibition of a fatty acid transporter impairs tumor progression in preclinical mo