Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Zihao Cong"'
Autor:
Ziyi Lu, Yueming Wu, Zihao Cong, Yuxin Qian, Xue Wu, Ning Shao, Zhongqian Qiao, Haodong Zhang, Yunrui She, Kang Chen, Hengxue Xiang, Bin Sun, Qian Yu, Yuan Yuan, Haodong Lin, Meifang Zhu, Runhui Liu
Publikováno v:
Bioactive Materials, Vol 6, Iss 12, Pp 4531-4541 (2021)
It is an urgent need to tackle drug-resistance microbial infections that are associated with implantable biomedical devices. Host defense peptide-mimicking polymers have been actively explored in recent years to fight against drug-resistant microbes.
Externí odkaz:
https://doaj.org/article/6f684ac9a0d34e64824ad60f51542bcc
Autor:
Jiayang Xie, Min Zhou, Yuxin Qian, Zihao Cong, Sheng Chen, Wenjing Zhang, Weinan Jiang, Chengzhi Dai, Ning Shao, Zhemin Ji, Jingcheng Zou, Ximian Xiao, Longqiang Liu, Minzhang Chen, Jin Li, Runhui Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Antibiotic resistance is a major issue in medicine and new antimicrobials for treating resistant infection are needed. Here, the authors report on antibacterial peptoid polymers, prepared via NNCA ring-opening polymerization, demonstrating antibacter
Externí odkaz:
https://doaj.org/article/5156e8b924224ead908f29cd19d0cd20
Autor:
Min Zhou, Ruxin Cui, Zhengjie Luo, Zihao Cong, Ning Shao, Ling Yuan, Jiawei Gu, Hongyan He, Runhui Liu
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 7, p 382 (2023)
Polyethylene glycol (PEG)–doxorubicin (DOX) conjugation is an important strategy to improve toxicity and enhance clinically therapeutic efficacy. However, with the frequent use of PEG-modified drugs, the accumulation of anti-PEG antibodies has beco
Externí odkaz:
https://doaj.org/article/695d1a9d054d479ca23ce05c43679125
Microbial Metabolite Inspired β‐Peptide Polymers Displaying Potent and Selective Antifungal Activity
Autor:
Donghui Zhang, Chao Shi, Zihao Cong, Qi Chen, Yufang Bi, Junyu Zhang, Kaiqian Ma, Shiqi Liu, Jiawei Gu, Minzhang Chen, Ziyi Lu, Haodong Zhang, Jiayang Xie, Ximian Xiao, Longqiang Liu, Weinan Jiang, Ning Shao, Sheng Chen, Min Zhou, Xiaoyan Shao, Yidong Dai, Maoquan Li, Lixin Zhang, Runhui Liu
Publikováno v:
Advanced Science, Vol 9, Iss 14, Pp n/a-n/a (2022)
Abstract Potent and selective antifungal agents are urgently needed due to the quick increase of serious invasive fungal infections and the limited antifungal drugs available. Microbial metabolites have been a rich source of antimicrobial agents and
Externí odkaz:
https://doaj.org/article/1c5e1b59e8d8420691ee26e01b87f3fa
Autor:
Min Zhou, Jingcheng Zou, Longqiang Liu, Ximian Xiao, Shuai Deng, Yueming Wu, Jiayang Xie, Zihao Cong, Zhemin Ji, Runhui Liu
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103124- (2021)
Summary: The fascinating functions of proteins and peptides in biological systems have attracted intense interest to explore their mimics using polymers, including polypeptides synthesized from polymerization. The folding, structures and functions of
Externí odkaz:
https://doaj.org/article/59d5667766c749e885201472c26b56ea
Autor:
Min Zhou, Zhemin Ji, Ximian Xiao, Longqiang Liu, Ruxin Cui, Zhengjie Luo, Zihao Cong, Runhui Liu
Publikováno v:
Polymer Chemistry. 14:1064-1071
Controllable and facile 2-oxazolines polymerization was demonstrated using TMSOTf as the initiator, which will contribute to the functional study and application of poly(2-oxazoline)s with diversified structures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d52f3049a48d720c6a0a3b5c8504ec
https://doi.org/10.1039/d2py01332k
https://doi.org/10.1039/d2py01332k
Autor:
Yueming Wu, Weinan Jiang, Zihao Cong, Kang Chen, Yunrui She, Chao Zhong, Wenjing Zhang, Minzhang Chen, Min Zhou, Ning Shao, Guohui Xiao, Xiaoyan Shao, Yidong Dai, Jian Fei, Gonghua Song, Runhui Liu
Publikováno v:
Journal of Medicinal Chemistry. 65:7296-7311
The high mortality rate of invasive fungal infections and quick emergence of drug-resistant fungal pathogens urgently call for potent antifungal agents. Inspired by the cell penetrating peptide (CPP) octaarginine (R8), we elongated to 28 residues pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c663dc2a495c743bb3d98d4354a8e9c4
https://doi.org/10.1021/acs.jmedchem.2c00274
https://doi.org/10.1021/acs.jmedchem.2c00274
Autor:
Ning Shao, Ling Yuan, Pengcheng Ma, Min Zhou, Ximian Xiao, Zihao Cong, Yueming Wu, Guohui Xiao, Jian Fei, Runhui Liu
Publikováno v:
Journal of the American Chemical Society. 144:7283-7294
Multidrug resistance to chemotherapeutic drugs is one of the major causes for the failure of cancer treatment. Therefore, there is an urgent need to develop anticancer agents that can combat multidrug-resistant cancers effectively and mitigate drug r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f8a28ba2c60e6f1b9a7949854402ce
https://doi.org/10.1021/jacs.2c00452
https://doi.org/10.1021/jacs.2c00452
Autor:
Yuxin Qian, Shuai Deng, Zihao Cong, Haodong Zhang, Ziyi Lu, Ning Shao, Sonia Abid Bhatti, Cong Zhou, Jiagao Cheng, Samuel H. Gellman, Runhui Liu
Publikováno v:
Journal of the American Chemical Society. 144:1690-1699
Interest in developing antibacterial polymers as synthetic mimics of host defense peptides (HPDs) has accelerated in recent years to combat antibiotic-resistant bacterial infections. Positively charged moieties are critical in defining the antibacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5976679116ced4440ade0698a4b5c227
https://doi.org/10.1021/jacs.1c10659
https://doi.org/10.1021/jacs.1c10659
Autor:
Haodong Zhang, Qi Chen, Jiayang Xie, Zihao Cong, Chuntao Cao, Wenjing Zhang, Donghui Zhang, Sheng Chen, Jiawei Gu, Shuai Deng, Zhongqian Qiao, Xinyue Zhang, Maoquan Li, Ziyi Lu, Runhui Liu
Publikováno v:
Science Advances. 9
Drug-resistant bacterial infections have caused serious threats to human health and call for effective antibacterial agents that have low propensity to induce antimicrobial resistance. Host defense peptide–mimicking peptides are actively explored,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cafa501d823631444955dc1ad73c5ed2
https://doi.org/10.1126/sciadv.abn0771
https://doi.org/10.1126/sciadv.abn0771