Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Zih‐ten Chen"'
Autor:
Yu‐Sung Cheng, Zih‐ten Chen, Tai‐Yan Liao, Chen Lin, Howard C‐H Shen, Ya‐Han Wang, Chi‐Wei Chang, Ren‐Shyan Liu, Rita P‐Y Chen, Pang‐hsien Tu
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 5, Pp 703-715 (2017)
Abstract Alzheimer's disease (AD) is the most common neurodegenerative disease. Imbalance between the production and clearance of amyloid β (Aβ) peptides is considered to be the primary mechanism of AD pathogenesis. This amyloid hypothesis is suppo
Externí odkaz:
https://doaj.org/article/1218aa1f0a354c7fbcfd29f025a528c2
Autor:
Zih Ten Chen, Ren Shyan Liu, Yu Sung Cheng, Pang-Hsien Tu, Chen Lin, Chi Wei Chang, Ya Han Wang, Rita P.-Y. Chen, Tai Yan Liao, Howard C.-H. Shen
Publikováno v:
EMBO Molecular Medicine
Alzheimer9s disease (AD) is the most common neurodegenerative disease. Imbalance between the production and clearance of amyloid β (Aβ) peptides is considered to be the primary mechanism of AD pathogenesis. This amyloid hypothesis is supported by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41cade9251f1718b8728c1bc01ccebb
http://europepmc.org/articles/PMC5412883
http://europepmc.org/articles/PMC5412883
Publikováno v:
Scientific Reports
Neprilysin (NEP) is the most important Aβ-degrading enzyme. Its expression level decreases with age and inversely correlated with amyloid accumulation, suggesting its correlation with the late-onset of Alzheimer’s disease. Recently, many reports s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ccd8cc931f9b6364635b115fc5c0ae
https://doi.org/10.1038/srep29760
https://doi.org/10.1038/srep29760
Autor:
Yu Sung Cheng, Tai Yan Liao, Chih Yun Lin, Rita P.-Y. Chen, Zih Ten Chen, Ren Shyan Liu, David Tat Wei Tan, Pang-Hsien Tu, Chi Wei Chang, Chen Lin, Woan Ing Twu
Publikováno v:
Journal of Alzheimer's disease : JAD. 53(3)
Amyloid-β (Aβ) aggregation in the brain plays a central and initiatory role in pathogenesis and/or progression of Alzheimer's disease (AD). Inhibiting Aβ aggregation is a potential strategy in the prevention of AD. A scavenger peptide, V24P(10-40)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656883b7df865ff0afb7dce828f382e4
https://pubmed.ncbi.nlm.nih.gov/27340844
https://pubmed.ncbi.nlm.nih.gov/27340844